15. Modeling Problems in Conservation Genetics Using Laboratory Animals
271
Frankham R, Nurthen RK (1981) Forging links between population and quantitative genetics. Theoretical and Applied Genetics 59:251–263
Frankham R, Briscoe DA, Nurthen RK (1978) Unequal crossing over at the rRNA locus as
a source of quantitative genetic variation. Nature 272:80–81
Frankham R, Smith GJ, Briscoe DA (1993) Effects on heterozygosity and reproductive
fitness of inbreeding with and without selection on fitness in Drosophila melanogaster.
Theoretical and Applied Genetics 86:1023–1027
Franklin IR (1980) Evolutionary change in small populations. In: Soul´ e ME,Wilcox BA
(eds) Conservation biology: an evolutionary-ecological perspective. Sinauer, Sunderland, MA, pp 135–140
Fuerst PA, Maruyama T (1986) Considerations on the conservation of alleles and of genic
heterozygosity in small managed populations. Zoo Biology 5:171–179
Gilligan DM, Woodworth LM, Montgomery ME, Briscoe DA, Frankham R (1997) Is
mutation accumulation a threat to the survival of endangered populations? Conservation
Biology 11:1235–1241
Hazel LN, Lush JL (1942) The efficiency of three methods of selection. Journal of Heredity
33:393–399
Hedrick PW (1994) Purging inbreeding depression and the probability of extinction: fullsib mating. Heredity 73:363–372
Hill WG (1981) Assessment of breeding value in selection programs. Proceeding of the
Second Conference of the Australian Association of Animal Breeding and Genetics,
University of Melbourne, Australia, pp 227–236
Hill WG (1982) Predictions of response to artificial selection from new mutations. Genetical Research 40:255–278
Hollingdale B (1971) Analyses of some genes from abdominal bristle number selection
lines in Drosophila melanogaster. Theoretical and Applied Genetics 41:292–301
Jimenez JA, Hughes KA, Alaks G, Graham L, Lacy RC (1994) An experimental study of
inbreeding depression in a natural habitat. Science 216:271–273
Jones LP, Frankham R, Barker JSF (1968) The effects of population size and selection
intensity in selection for a quantitative character in Drosophila. II. Long-term response
to selection. Genetical Research 12:249–266
Kimura M, Crow JF (1963) On the maximum avoidance of inbreeding. Genetical Research
4:399– 415
Lande R (1995) Mutation and conservation. Conservation Biology 9:782–791
Lande R, Barrowclough GF (1987) Effective population size, genetic variation, and their
use in population management. In: Soul´ e ME (ed) Viable populations for conservation.
Cambridge University Press, Cambridge, UK, pp 87–123
Latter BDH (1964) Selection for a threshold character in Drosophila. I. An analysis of
phenotypic variance on the underlying scale. Genetical Research 5:198–210
Leberg PL (1992) Effects of a population bottleneck on genetic diversity as measured by
allozyme electrophoresis. Evolution 46:474 – 494
Loebel DA, Nurthen RK, Frankham R, Briscoe DA, Craven D (1992) Modeling problems
in conservation genetics using captive Drosophila populations: consequences of equalizing founder representation. Zoo Biology 11:319–332
Lopez-Fanjul C, Caballero A (1990) The effect of artificial selection on new mutations for
a quantitative trait. Proceedings of the 4th World Congress on Genetics Applied to
Livestock Production 13:210–218
Lush JL (1945) Animal breeding plans, 3rd ed. Iowa State College Press, Ames, IA
Margan SH, Nurthen RK, Montgomery ME, Woodworth LM, Briscoe DA, Frankham R
271
Frankham R, Nurthen RK (1981) Forging links between population and quantitative genetics. Theoretical and Applied Genetics 59:251–263
Frankham R, Briscoe DA, Nurthen RK (1978) Unequal crossing over at the rRNA locus as
a source of quantitative genetic variation. Nature 272:80–81
Frankham R, Smith GJ, Briscoe DA (1993) Effects on heterozygosity and reproductive
fitness of inbreeding with and without selection on fitness in Drosophila melanogaster.
Theoretical and Applied Genetics 86:1023–1027
Franklin IR (1980) Evolutionary change in small populations. In: Soul´ e ME,Wilcox BA
(eds) Conservation biology: an evolutionary-ecological perspective. Sinauer, Sunderland, MA, pp 135–140
Fuerst PA, Maruyama T (1986) Considerations on the conservation of alleles and of genic
heterozygosity in small managed populations. Zoo Biology 5:171–179
Gilligan DM, Woodworth LM, Montgomery ME, Briscoe DA, Frankham R (1997) Is
mutation accumulation a threat to the survival of endangered populations? Conservation
Biology 11:1235–1241
Hazel LN, Lush JL (1942) The efficiency of three methods of selection. Journal of Heredity
33:393–399
Hedrick PW (1994) Purging inbreeding depression and the probability of extinction: fullsib mating. Heredity 73:363–372
Hill WG (1981) Assessment of breeding value in selection programs. Proceeding of the
Second Conference of the Australian Association of Animal Breeding and Genetics,
University of Melbourne, Australia, pp 227–236
Hill WG (1982) Predictions of response to artificial selection from new mutations. Genetical Research 40:255–278
Hollingdale B (1971) Analyses of some genes from abdominal bristle number selection
lines in Drosophila melanogaster. Theoretical and Applied Genetics 41:292–301
Jimenez JA, Hughes KA, Alaks G, Graham L, Lacy RC (1994) An experimental study of
inbreeding depression in a natural habitat. Science 216:271–273
Jones LP, Frankham R, Barker JSF (1968) The effects of population size and selection
intensity in selection for a quantitative character in Drosophila. II. Long-term response
to selection. Genetical Research 12:249–266
Kimura M, Crow JF (1963) On the maximum avoidance of inbreeding. Genetical Research
4:399– 415
Lande R (1995) Mutation and conservation. Conservation Biology 9:782–791
Lande R, Barrowclough GF (1987) Effective population size, genetic variation, and their
use in population management. In: Soul´ e ME (ed) Viable populations for conservation.
Cambridge University Press, Cambridge, UK, pp 87–123
Latter BDH (1964) Selection for a threshold character in Drosophila. I. An analysis of
phenotypic variance on the underlying scale. Genetical Research 5:198–210
Leberg PL (1992) Effects of a population bottleneck on genetic diversity as measured by
allozyme electrophoresis. Evolution 46:474 – 494
Loebel DA, Nurthen RK, Frankham R, Briscoe DA, Craven D (1992) Modeling problems
in conservation genetics using captive Drosophila populations: consequences of equalizing founder representation. Zoo Biology 11:319–332
Lopez-Fanjul C, Caballero A (1990) The effect of artificial selection on new mutations for
a quantitative trait. Proceedings of the 4th World Congress on Genetics Applied to
Livestock Production 13:210–218
Lush JL (1945) Animal breeding plans, 3rd ed. Iowa State College Press, Ames, IA
Margan SH, Nurthen RK, Montgomery ME, Woodworth LM, Briscoe DA, Frankham R