198
4 The Measurement Process in Chemistry
• Draw a detailed scheme for each process.
• Comment on the calibration procedures and discern between method and
equipment calibration.
• Discuss the way the final results are computed and expressed.
• Discussion
• Compare the CMPs considered in a critical manner and justify the differences among the methods employed.
• Identify common and differential sources of error potentially affecting the
quality of the final results.
• Comment on the significance of the results to diagnoses based on
comparisons with normal values.
• Expanding the Seminar
• Find expeditious CMPs for determining the clinical parameters considered
in this seminar (and also in others) developed by manufacturers and available at chemist's shops as test kits for urine and blood based on visual comparisons or photometric or electrochemical measurements.
• Describe the selected procedures.
• Compare conventional CMPs and those based on test kits.
Seminar 4.4
Selecting Analytical Procedures from the Literature
• Learning objectives
• To introduce the analytical literature concerned with the second
fundamental component of Analytical Chemistry, and also with the first
(Fig. l.8).
• To classify methods directly resulting from R&D (primary literature) on
the one hand, and recommended, official and standard methods (secondary literature) on the other.
• To help students develop critical awareness in selecting suitable methods,
taking into account the factors of Fig. 4.3.
• Sources
• Handbooks, standards, etc., containing descriptions of analytical methods.
• Computer access to searches of methods published in the primary scientific literature (e. g. the Analytical Abstracts database of the Royal Society of
Chemistry or the Chemical Abstracts database of the American Chemical
Society).
• Volumes of prime analytical journals (e. g. Analytical Chemistry, Analytica
Chimica Acta, The Analyst, Fresenius' Journal of Analytical Chemistry).
• Suggested criteria for searching, by objective
Objective 1. Search handbooks for specific methods for each sample-analyte
couple in a specific field. Examples:
• Food analysis (determination of total protein in milk).
4 The Measurement Process in Chemistry
• Draw a detailed scheme for each process.
• Comment on the calibration procedures and discern between method and
equipment calibration.
• Discuss the way the final results are computed and expressed.
• Discussion
• Compare the CMPs considered in a critical manner and justify the differences among the methods employed.
• Identify common and differential sources of error potentially affecting the
quality of the final results.
• Comment on the significance of the results to diagnoses based on
comparisons with normal values.
• Expanding the Seminar
• Find expeditious CMPs for determining the clinical parameters considered
in this seminar (and also in others) developed by manufacturers and available at chemist's shops as test kits for urine and blood based on visual comparisons or photometric or electrochemical measurements.
• Describe the selected procedures.
• Compare conventional CMPs and those based on test kits.
Seminar 4.4
Selecting Analytical Procedures from the Literature
• Learning objectives
• To introduce the analytical literature concerned with the second
fundamental component of Analytical Chemistry, and also with the first
(Fig. l.8).
• To classify methods directly resulting from R&D (primary literature) on
the one hand, and recommended, official and standard methods (secondary literature) on the other.
• To help students develop critical awareness in selecting suitable methods,
taking into account the factors of Fig. 4.3.
• Sources
• Handbooks, standards, etc., containing descriptions of analytical methods.
• Computer access to searches of methods published in the primary scientific literature (e. g. the Analytical Abstracts database of the Royal Society of
Chemistry or the Chemical Abstracts database of the American Chemical
Society).
• Volumes of prime analytical journals (e. g. Analytical Chemistry, Analytica
Chimica Acta, The Analyst, Fresenius' Journal of Analytical Chemistry).
• Suggested criteria for searching, by objective
Objective 1. Search handbooks for specific methods for each sample-analyte
couple in a specific field. Examples:
• Food analysis (determination of total protein in milk).