Biomimetic Organocatalytic C–C-Bond Formations
95
Scheme 29. Thiazolin-2-ylidene catalyzed intramolecular crossed benzoin reactions
get was found in the cis-bicyclic lactam 118, which was obtained in
a diastereo- and enantioselective manner in five steps starting from cyclopentanone (116) in 36% yield following a modified procedure developed by Omar and Frahm (Scheme 30) (Omar and Frahm 1989, 1990).
95
Scheme 29. Thiazolin-2-ylidene catalyzed intramolecular crossed benzoin reactions
get was found in the cis-bicyclic lactam 118, which was obtained in
a diastereo- and enantioselective manner in five steps starting from cyclopentanone (116) in 36% yield following a modified procedure developed by Omar and Frahm (Scheme 30) (Omar and Frahm 1989, 1990).