CHAPTER 15 . Toxic Effects of Organometallic Compounds towards Marine Biota
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Table 15.14. Genotoxic activity: mitotic metaphase chromosomal damage in Aphanius Jasciatus specimens treated with RzSnClz, RzSnClpenG, R3SnCI and R3SnCIpenGNa (penG = penicillin G; R = methyl,
butyl and phenyl), adapted from Vitturi et al. (1994)
Compound
Conc.
Time
(mol dm -J) interval (h)
No. of meta phases
Normal Fragments Irregular PseudoIrregular Total
outlines chiasmata staining spreads
MezSnClpenG
10- 5
24
4
30
28
40
70
48
32
8
39
10- 7
24
4
52
22
36
60
48
26
6
36
MezSnCl z
10- 5
24
18
23
22
30
48
16
25
18
40
10- 7
24
12
44
32
28
80
48
40
39
38
70
MeJSnClpenGNa
10- 5
Died after a treatment of 3 hours
10- 7
24
15
16
25
36
48
5
22
23
32
42
MeJSnCI
10- 5
Died after a treatment of 3 hours
10- 7
24
2
12
20
18
38
48
18
24
20
40
BuzSnClpenG
10- 5
24
4
2
40
16
32
50
48
4
3
30
8
36
40
10- 7
24
16
46
4
40
80
48
40
15
36
50
BUzSnCl z
10- 5
24
4
41
16
32
50
48
2
28
23
18
35
10- 7
24
10
50
10
44
64
48
4
35
8
40
50
BuJSnClpenGNa
10- 5
Died after a treatment of 3 hours
10- 7
24
12
15
20
30
48
14
18
24
28
Bu J 5nCI
10- 5
Died after a treatment of 3 hours
10- 7
24
30
18
36
28
46
48
Died after a treatment of 40 hours
Ph z 5nClpenG
10- 5
24
8
4
50
8
30
60
48
6
9
8
10
10- 7
24
42
29
22
50
48
48
27
25
58