S-Glycosylation
3.5
693
3.3 Examples
With the continuous development of new methods and improvement of old methods, the construction of more and more complex thiooligosaccharides has become possible. Two recently
published examples of this are shown in > Scheme 66 and > Scheme 67. In > Scheme 66 the
synthesis of thio analogues of Lewis x and sialyl-Lewis x, using exclusively non-anomeric
thiols in both acid-and base-catalyzed glycosylation reactions, is summarized [195].
⊡ Scheme 67
3.5
693
3.3 Examples
With the continuous development of new methods and improvement of old methods, the construction of more and more complex thiooligosaccharides has become possible. Two recently
published examples of this are shown in > Scheme 66 and > Scheme 67. In > Scheme 66 the
synthesis of thio analogues of Lewis x and sialyl-Lewis x, using exclusively non-anomeric
thiols in both acid-and base-catalyzed glycosylation reactions, is summarized [195].
⊡ Scheme 67