C=C Bond Formation
2.6
367
⊡ Scheme 39
⊡ Scheme 40
⊡ Figure 9
Application of unsaturated sugars in the synthesis of valienamine
The carbocycles substituted at the double bond (with for example, an alkoxymethylene group)
can also be prepared from the appropriately functionalized unsaturated sugars. Synthesis of
α-glucosidase inhibitor—valienamine—was realized from unsaturated sugar chirons as shown
in > Fig. 9 [86].