Marine Algal Bioactivities 121
Bromophenols
Vidalols
Rhodophyta
Rhodomelaceae
Vidalia obtusiloba
Inhibition of phospholipase A
2
El Gamal 2010
Dienes
3-0-b-D-glucopyranosy-lstigmasta-5,25-diene
Chlorophyta
Ulvaceae
Ulva lactuca
El Gamal 2010
Diphenyl ethers
2-(20,40-dibromophenoxy)-4,6-dibromoanisol
Chlorophyta
Cladophoraceae
Cladophora fascicularis
El Gamal 2010
Flavonoids
Catechol
Rhodophyta
Bangiaceae
Porphyra dentata
LPS-induced macrophages
Jaswir and Monsur 2011;
Kazłowska et al. 2010
Hesperidin
Rhodophyta
Bangiaceae
Porphyra dentata
LPS-induced macrophages
Rutin
Rhodophyta
Bangiaceae
Porphyra dentata
LPS-induced macrophages
Stypotriol triacetate
Ochrophyta
Dictyotaceae
Stypopodium
flabelliforme
Inhibition of LTB4 and TXB2,
modulation of COX pathway and
inhibition of phospholipase A
2
D’ Orazio et al. 2012
Peptides
cis- and trans-ceratospongamide
Rhodophyta
Lomentariaceae
Ceratodictyon
spongiosum
Inhibition of phospholipase A
2
El Gamal 2010
Pigments
Pheophytin
Chlorophyta
Ulvaceae
Enteromorpha prolifera Production of O
2
–
in
macrophages, chemotaxis of
human PMNs to FMLP and ear
oedema
Okai and Higashi-Okai
1997
Fucoxanthin
Ochrophyta
Ishigeaceae
Ishige okamurae
NO, PGE
2
, iNOS, COX-2,
TNF-α, IL-1β, and IL-6 levels,
degradation of IкB-α and
Phosphorylation of p50, p60,
and MAPKs in LPS-induced
macrophages
Kim et al. 2010
Ochrophyta
Sargassaceae
Myagropsis myagroides LPS-induced NO production,
PGE
2
, iNOS, COX-2, IL-1β, IL6, and TNF-α
Heo et al. 2010
Fraction/Compound
Marine Algae
Assay(s)
1
Reference(s)
Structure/Name
Phylum
Family
Specie
Table 2.
Anti-inflammatory compounds from marine algae.
Table 2 contd. …