Table 5.1. Categories of Toxicity for Precautionary Labeling in the Federal Insecticide, Fungicide, and Rodenticide Acf',b
Inhalation LC~
Toxicity
Signal
Oral
LD50
Dennal LD~
Dust or mist
Gas or vapor
category
word
(mglkg)
(mglkg)
(mg/liter)
(ppm)
Eye effects
Skin irritation
DANGER
50 or less
200 or less
2 or less
200 or less
Irreversible corneal
Severe irritation
PoISON"
opacity at 7 days
or damage at
(fatal)
12hr
II
WARNING
50 through
500
200 through
2000
2 through
20
200 through
2000
Corneal opacity
Moderate
(may be
reversible within
irritation at
fatal)
7 days,
or
12hr
irritation
persisting for 7
days
III
CAUTION
500 through
2,000-20,000
20-200
2,000-20,000
No corneal
Mild or slight
5000
opacity,
irritation at
irritation
12hr
reversible within
7 days
IV
CAUTION
5000 or greater
20,000 or greater
200 or greater
20,000 or greater
No irritation
No irritation at
12hr
• Adapted from
EPA toxicology guidelines.
b
All labels must state: "Keep Out of Reach of Children."
, Skull and crossbones must appear near word
POISON.
Inhalation LC~
Toxicity
Signal
Oral
LD50
Dennal LD~
Dust or mist
Gas or vapor
category
word
(mglkg)
(mglkg)
(mg/liter)
(ppm)
Eye effects
Skin irritation
DANGER
50 or less
200 or less
2 or less
200 or less
Irreversible corneal
Severe irritation
PoISON"
opacity at 7 days
or damage at
(fatal)
12hr
II
WARNING
50 through
500
200 through
2000
2 through
20
200 through
2000
Corneal opacity
Moderate
(may be
reversible within
irritation at
fatal)
7 days,
or
12hr
irritation
persisting for 7
days
III
CAUTION
500 through
2,000-20,000
20-200
2,000-20,000
No corneal
Mild or slight
5000
opacity,
irritation at
irritation
12hr
reversible within
7 days
IV
CAUTION
5000 or greater
20,000 or greater
200 or greater
20,000 or greater
No irritation
No irritation at
12hr
• Adapted from
EPA toxicology guidelines.
b
All labels must state: "Keep Out of Reach of Children."
, Skull and crossbones must appear near word
POISON.
