When a cell is infected with HIV, cell membrane fusion results in the formation
of a syncytium to produce a large multinuclear cell. Recently, the author’s laboratory found that 6,6’-bieckol from the brown alga Ecklonia cava notably suppressed syncytium formation in HIV-infected cells, suggesting possible application
in treatments for AIDS (Fig. 8.5).
Several types of antibiotics have been isolated from a marine microorganism
discovered near a wastewater treatment site outlet on the Mediterranean island of
Fig. 8.3 Substance isolated from the marine sponges Ptilocaulis spiculifer and Hemimycale sp.
Fig. 8.4 Substance isolated from the sea squirt Lissoclinum patella
Fig. 8.5 Disruption of syncytium formation in HIV-infected cells with 6,6’-bieckol from E. cava
(Artan et al. 2008; Karadeniz et al. 2011)
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8 Developing Functional Materials with Marine Organisms
of a syncytium to produce a large multinuclear cell. Recently, the author’s laboratory found that 6,6’-bieckol from the brown alga Ecklonia cava notably suppressed syncytium formation in HIV-infected cells, suggesting possible application
in treatments for AIDS (Fig. 8.5).
Several types of antibiotics have been isolated from a marine microorganism
discovered near a wastewater treatment site outlet on the Mediterranean island of
Fig. 8.3 Substance isolated from the marine sponges Ptilocaulis spiculifer and Hemimycale sp.
Fig. 8.4 Substance isolated from the sea squirt Lissoclinum patella
Fig. 8.5 Disruption of syncytium formation in HIV-infected cells with 6,6’-bieckol from E. cava
(Artan et al. 2008; Karadeniz et al. 2011)
234
8 Developing Functional Materials with Marine Organisms