2.3 Holographic Study with Electrophysiological Control …
129
is a multi-component factor that is why it is not always possible to differentiate
the impact of the compression and connected with its toxic impacts of partial pressures from stress reactions [352]. Most intensive studies are conducted on the issue of
hyperbary impact on the biochemical level [349, 353, 354]. The study of non-oxygen
factors of hyperbaric impact on human and animal organisms is significantly developed by the cellular studies. The next important step in the methodical improvement
of researches is to study excitable tissues of isolated preparations functioning under
hydrostatic pressure [355–357].
Obtained from isolated preparations of excitable tissues of animals heart, experimental data are of prime importance for interpretation of pathological states observed
in divers organism during diving. Problems with excitement conduction are the
cause for observed hyperbaric changes of human blood circulation, in particular
bradycardia [355].
The facts of hyperbaric impact on the cross-striped tissue were found as well both
by animals [358] and by humans [359]. By divers under test during the simulation
diving, the researchers studied maximal force and time of gastrocnemius muscle
contraction during development under the influence of Hoffman reflex electrostimulation as well as of the direct motor reaction stimulation. While diving maximal
contraction force increased by 40–60% relative to the control measurements. The
reasons of this phenomenon are not fully clear; moreover, there were facts of injurious
impact of hydrostatic pressure on the muscle [360]. Three-dimensional compression
effect plays an important role in the influence of high pressures on the human and
on animals [361].
Analysis of biochemical adaptation by living organisms to high pressures is
evidence of the fact that many processes important for life react to hyperbary
with slowdown or acceleration of product reaction generation. Meanwhile, the ratio
of reagents volume and reaction products plays an important role [362]. These
phenomena are more important on the forming stage and on the stage of energy
provision of an organism. Moreover, knowledge about the hyperbary impact directly
on the functions of the excitable tissues such as excitability, processes of its provision, distribution and transmission are of great importance. Namely, the efforts of
the researchers who seek reasons of emergence of so-called high pressures neural
syndrome [363] are directed to the study of these processes. The conducted studies
showed a complex multi-parametric character of changes in metabolism processes
of different substances that provide and modulate the synoptic excitability transmission. It is connected, for example, with alterations of force and duration of convulsive
contractions of human muscles under hyperbary [364], isometric muscle contraction
of intact animals under high pressure [365].
While studying hyperbary impact on excitable tissues and analyzing the results
obtained from the whole organism, the complex character of this physical factor
should be taken into account, which influences functioning of different systems of
an organism: immune, hematopoietic, respiratory, cardiovascular, endocrine [366].
Thereby studies of hyperbary impact on isolated preparations of excitable tissues
gain importance. Though such an approach strictly constrains the interpretation of
129
is a multi-component factor that is why it is not always possible to differentiate
the impact of the compression and connected with its toxic impacts of partial pressures from stress reactions [352]. Most intensive studies are conducted on the issue of
hyperbary impact on the biochemical level [349, 353, 354]. The study of non-oxygen
factors of hyperbaric impact on human and animal organisms is significantly developed by the cellular studies. The next important step in the methodical improvement
of researches is to study excitable tissues of isolated preparations functioning under
hydrostatic pressure [355–357].
Obtained from isolated preparations of excitable tissues of animals heart, experimental data are of prime importance for interpretation of pathological states observed
in divers organism during diving. Problems with excitement conduction are the
cause for observed hyperbaric changes of human blood circulation, in particular
bradycardia [355].
The facts of hyperbaric impact on the cross-striped tissue were found as well both
by animals [358] and by humans [359]. By divers under test during the simulation
diving, the researchers studied maximal force and time of gastrocnemius muscle
contraction during development under the influence of Hoffman reflex electrostimulation as well as of the direct motor reaction stimulation. While diving maximal
contraction force increased by 40–60% relative to the control measurements. The
reasons of this phenomenon are not fully clear; moreover, there were facts of injurious
impact of hydrostatic pressure on the muscle [360]. Three-dimensional compression
effect plays an important role in the influence of high pressures on the human and
on animals [361].
Analysis of biochemical adaptation by living organisms to high pressures is
evidence of the fact that many processes important for life react to hyperbary
with slowdown or acceleration of product reaction generation. Meanwhile, the ratio
of reagents volume and reaction products plays an important role [362]. These
phenomena are more important on the forming stage and on the stage of energy
provision of an organism. Moreover, knowledge about the hyperbary impact directly
on the functions of the excitable tissues such as excitability, processes of its provision, distribution and transmission are of great importance. Namely, the efforts of
the researchers who seek reasons of emergence of so-called high pressures neural
syndrome [363] are directed to the study of these processes. The conducted studies
showed a complex multi-parametric character of changes in metabolism processes
of different substances that provide and modulate the synoptic excitability transmission. It is connected, for example, with alterations of force and duration of convulsive
contractions of human muscles under hyperbary [364], isometric muscle contraction
of intact animals under high pressure [365].
While studying hyperbary impact on excitable tissues and analyzing the results
obtained from the whole organism, the complex character of this physical factor
should be taken into account, which influences functioning of different systems of
an organism: immune, hematopoietic, respiratory, cardiovascular, endocrine [366].
Thereby studies of hyperbary impact on isolated preparations of excitable tissues
gain importance. Though such an approach strictly constrains the interpretation of