2.2 Holographic Study of Structural and Functional Characteristics …
95
neuromotor apparatus and microgemocirculation that strengthens compensatoryadaptive organism reactions in the conditions of model pathology. Consequently,
ILBI influences circulating blood and has biostimulating effect, normalizes the state
of the important functional systems and organs that allows using this method of nondrug therapy in treating different pathologies including the diseases of the nervous
system: disseminated sclerosis, cerebrovascular pathology, vertebragenous diseases
of the peripheral nervous system (PNS) [272, 273].
In neurosurgery, ILBI used in treating craniocerebral injury, tumors, vascular
diseases and led to the disappearance of blood metabolic acidosis, normalized blood
osmolality, microcirculation improvement [274]. The regression of clinic symptomatology was characterized by the decrease of cerebral damage (the degree of consciousness disorder, the intensity of psychomotor damages, the intensity of headache).
Brain edema, which was typical to the neurosurgery patients in 3–5 days after the
operation, stopped to progress or was ill-defined. The regression of nidal neurologic
symptomatology, mainly of cortical genesis, was marked [275]. It allows concluding
that neurosurgery patients had slighter postoperative period after ILBI-therapy.
In the works [29, 34, 35, 37, 39–41, 43, 45, 48, 53, 77], there are the results of
the studies on the clinic use of ILBI under traumatic damages of peripheral nerves
directly after open treatment—neuroraffia.
It is considered promising to take microhemocirculation indicators as criteria
for severity and prediction of outcomes of various pathological conditions. [276].
However, the question of objective evaluation of microhemocirculation and the
effect of laser radiation on it has not been fully resolved due to the lack of reliable
noninvasive methods of study.
The development of unique possibilities of contactless noninvasive speckleoptical diagnostics of cutaneous blood flow changes under the damages of peripheral
nerves of different genesis will allow quantitative assessment of the effectiveness of
ILBI use on early stages of restoring-regenerating process.
Using the method of speckle-optical myography, it is possible to get objective
criteria of miotonus damages and the damages of the contractive activity of denervated muscles and also to assess their function restoration degree under the ILBI
influence [277–279].
For the diagnostics of hypoxic tissue changes by damaged peripheral nerves, it is
very important to have the information about the level of cutaneous chromophores,
hemoglobin and oxyhemoglobin in cutaneous blood flow [279].
Spectral analysis is the most effective method for receiving this type of information
[20, 22–24, 25]. The studies of absorption spectrum of animal blood preparation
using three-wavelength spectrophotometric method under ILBI allow estimating the
influence of LILI (λ = 0.6328 μm and 0.85 μm) on such important index of the
blood oxygen transport function as the degree of oxygenation and use this criterion
as a basis for the objectification of the damages of blood oxygen transport function
under different peripheral nerves damages (traumatic damages of nerve trunks, partial
ischemia of animal hind limb with the development of ischemia neuropathy of sciatic
nerve) and also study the possibility of this criterion correction by ILBI.
95
neuromotor apparatus and microgemocirculation that strengthens compensatoryadaptive organism reactions in the conditions of model pathology. Consequently,
ILBI influences circulating blood and has biostimulating effect, normalizes the state
of the important functional systems and organs that allows using this method of nondrug therapy in treating different pathologies including the diseases of the nervous
system: disseminated sclerosis, cerebrovascular pathology, vertebragenous diseases
of the peripheral nervous system (PNS) [272, 273].
In neurosurgery, ILBI used in treating craniocerebral injury, tumors, vascular
diseases and led to the disappearance of blood metabolic acidosis, normalized blood
osmolality, microcirculation improvement [274]. The regression of clinic symptomatology was characterized by the decrease of cerebral damage (the degree of consciousness disorder, the intensity of psychomotor damages, the intensity of headache).
Brain edema, which was typical to the neurosurgery patients in 3–5 days after the
operation, stopped to progress or was ill-defined. The regression of nidal neurologic
symptomatology, mainly of cortical genesis, was marked [275]. It allows concluding
that neurosurgery patients had slighter postoperative period after ILBI-therapy.
In the works [29, 34, 35, 37, 39–41, 43, 45, 48, 53, 77], there are the results of
the studies on the clinic use of ILBI under traumatic damages of peripheral nerves
directly after open treatment—neuroraffia.
It is considered promising to take microhemocirculation indicators as criteria
for severity and prediction of outcomes of various pathological conditions. [276].
However, the question of objective evaluation of microhemocirculation and the
effect of laser radiation on it has not been fully resolved due to the lack of reliable
noninvasive methods of study.
The development of unique possibilities of contactless noninvasive speckleoptical diagnostics of cutaneous blood flow changes under the damages of peripheral
nerves of different genesis will allow quantitative assessment of the effectiveness of
ILBI use on early stages of restoring-regenerating process.
Using the method of speckle-optical myography, it is possible to get objective
criteria of miotonus damages and the damages of the contractive activity of denervated muscles and also to assess their function restoration degree under the ILBI
influence [277–279].
For the diagnostics of hypoxic tissue changes by damaged peripheral nerves, it is
very important to have the information about the level of cutaneous chromophores,
hemoglobin and oxyhemoglobin in cutaneous blood flow [279].
Spectral analysis is the most effective method for receiving this type of information
[20, 22–24, 25]. The studies of absorption spectrum of animal blood preparation
using three-wavelength spectrophotometric method under ILBI allow estimating the
influence of LILI (λ = 0.6328 μm and 0.85 μm) on such important index of the
blood oxygen transport function as the degree of oxygenation and use this criterion
as a basis for the objectification of the damages of blood oxygen transport function
under different peripheral nerves damages (traumatic damages of nerve trunks, partial
ischemia of animal hind limb with the development of ischemia neuropathy of sciatic
nerve) and also study the possibility of this criterion correction by ILBI.