36
M. A. Espinosa-Hernandez et al.
Table 2.1
(continued)
BioMEMS platform
Main components
Fabrication strategy Mechanisms of
operation
Detected analyte
Specifics
References
RCA-based biosensor
for attomolar detection
• Polymerase
• MB amplification
template
• MB/GDNA probe
• Spectrophotometer
• Electrophoresis
analyzer
N/A
miRNA triggered MB
mediated strand
displacement to release
nicking triggers
cyclically, leading to a
TIRCA. This result
was vast production of
GDNA, which joining
with hemin, form an
HRP mimic, has
catalyzed the
colorimetric reaction
The machine united
the advantages of
enzymatic signal
amplification and
TIRCA. It allowed
a decrease in
background noise
and improvement
in stringent target
recognition as well
as sensitivity
Li (2016)
Paper-based analytical device (PAD); Pyrrolidinyl peptide nucleic acid (acpcPNA); Silver nanoparticles (AgNPs); Polydimethylsiloxane (PDMS); Middle
East Respiratory Syndrome (MERS); Tuberculosis (TB); Middle East Respiratory Syndrome coronavirus (MERS-CoV); Human Papillomavirus (HPV);
Enzyme-linked immunosorbent assays (ELISA); Gold nanoparticles (AuNPs); Poly(ethylene glycol) (PEG); Immunoglobulin G (IgG); Paper-based enzymelinked immunosorbent assay (P-ELISA); Poly(methyl methacrylate) (PMMA); Loop-mediated isothermal amplification (LAMP); Escherichia coli (E. coli);
Polyvinylchloride (PVC); Acetylcholinesterase (AChE); Acetylthiocholine iodide (ATChI); Microfluidic paper-based analytical device (μPAD); Hepatitis B
Surface Antigen (HBsAg); 3,3
,5,5
-tetramethylbenzidine (TMB); Microfluidic cloth-based analytical device (μCAD); Chemically patterned
μPAD (C-μPAD);
Chemical vapor deposition (CVD); Trichlorosilane (TCS); Graphene Quantum Dots (GDQs); Magnetic nanoparticles (MNPs); Acetylcholine (ACh); Polystyrene
(PS); Glucose (GLU); Triglycerides (TG); Total cholesterol (TC); 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC); N-hydroxysuccinimide (NHS); Antihuman Chorionic Gonadotropin Gα (anti-hCGα); Human Chorionic Gonadotropin (hCG); Polycarbonate (PC); Point of care (POC); Pressure sensitive adhesive
(PSA); Complementary metal oxide semiconductor (CMOS); Lab-on-a-Printed Circuit Board (LoPCB); Interferon Gamma (IFNγ); Copper (Cu); Printed Circuit
Board (PCB); Pressure sensitive adhesive (PSA); Revulsion per minute (RPM); Limit of detection (LOD); Rolling circle amplification (RCA); Molecular beacon
(MB); G-rich DNA (GDNA); MicroRNA (miRNA); Toehold initiated rolling circle amplification (TIRCA); Horseradish peroxidase (HRP)
M. A. Espinosa-Hernandez et al.
Table 2.1
(continued)
BioMEMS platform
Main components
Fabrication strategy Mechanisms of
operation
Detected analyte
Specifics
References
RCA-based biosensor
for attomolar detection
• Polymerase
• MB amplification
template
• MB/GDNA probe
• Spectrophotometer
• Electrophoresis
analyzer
N/A
miRNA triggered MB
mediated strand
displacement to release
nicking triggers
cyclically, leading to a
TIRCA. This result
was vast production of
GDNA, which joining
with hemin, form an
HRP mimic, has
catalyzed the
colorimetric reaction
The machine united
the advantages of
enzymatic signal
amplification and
TIRCA. It allowed
a decrease in
background noise
and improvement
in stringent target
recognition as well
as sensitivity
Li (2016)
Paper-based analytical device (PAD); Pyrrolidinyl peptide nucleic acid (acpcPNA); Silver nanoparticles (AgNPs); Polydimethylsiloxane (PDMS); Middle
East Respiratory Syndrome (MERS); Tuberculosis (TB); Middle East Respiratory Syndrome coronavirus (MERS-CoV); Human Papillomavirus (HPV);
Enzyme-linked immunosorbent assays (ELISA); Gold nanoparticles (AuNPs); Poly(ethylene glycol) (PEG); Immunoglobulin G (IgG); Paper-based enzymelinked immunosorbent assay (P-ELISA); Poly(methyl methacrylate) (PMMA); Loop-mediated isothermal amplification (LAMP); Escherichia coli (E. coli);
Polyvinylchloride (PVC); Acetylcholinesterase (AChE); Acetylthiocholine iodide (ATChI); Microfluidic paper-based analytical device (μPAD); Hepatitis B
Surface Antigen (HBsAg); 3,3
,5,5
-tetramethylbenzidine (TMB); Microfluidic cloth-based analytical device (μCAD); Chemically patterned
μPAD (C-μPAD);
Chemical vapor deposition (CVD); Trichlorosilane (TCS); Graphene Quantum Dots (GDQs); Magnetic nanoparticles (MNPs); Acetylcholine (ACh); Polystyrene
(PS); Glucose (GLU); Triglycerides (TG); Total cholesterol (TC); 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC); N-hydroxysuccinimide (NHS); Antihuman Chorionic Gonadotropin Gα (anti-hCGα); Human Chorionic Gonadotropin (hCG); Polycarbonate (PC); Point of care (POC); Pressure sensitive adhesive
(PSA); Complementary metal oxide semiconductor (CMOS); Lab-on-a-Printed Circuit Board (LoPCB); Interferon Gamma (IFNγ); Copper (Cu); Printed Circuit
Board (PCB); Pressure sensitive adhesive (PSA); Revulsion per minute (RPM); Limit of detection (LOD); Rolling circle amplification (RCA); Molecular beacon
(MB); G-rich DNA (GDNA); MicroRNA (miRNA); Toehold initiated rolling circle amplification (TIRCA); Horseradish peroxidase (HRP)