2 Bio-microelectromechanical Systems (BioMEMS) …
29
Table 2.1
(continued)
BioMEMS platform
Main components
Fabrication strategy Mechanisms of
operation
Detected analyte
Specifics
References
Compact embeddable
μCAD
• Cotton fabrics/cloth
• Dual inlet
Wax patterning
technique was
utilized to pattern
microfluidic
channels on
scoured-cotton cloth
fabric and the 3D
colorimetric
microfluidic device
was made by folding
a 2D pattern
Solutions of the
respective colorimetric
reagents were pipetted
into the detection
zones. The inlet point
was immersed into the
urine. The sample
analyte was introduced
through an inlet point
to react with the
reagents
• GLU
• Nitrite
• Protein
The easy to pattern,
inexpensive and
environmentally
friendly device was
stable for a week
proving useful for
applications in
underdeveloped
areas
Nilghaz
et al. (2015)
C-μPAD
Chromatography paper The hydrophobic
barriers were made
by CVD of TCS on a
chromatography
paper
A pattern was cut out
onto a reactive surface
that was glued to paper
surface and placed
inside the CD
chamber. A
colorimetric reagent
was immobilized for a
stationary and uniform
reaction through
thermal condensation
coupling method
• GLU
• Metals
More complex
detection chambers
and higher degree
of reliability
resulted from this
device by
controlling
temperature,
pattern size, and
CVD duration
Lam et al.
(2017)
(continued)
29
Table 2.1
(continued)
BioMEMS platform
Main components
Fabrication strategy Mechanisms of
operation
Detected analyte
Specifics
References
Compact embeddable
μCAD
• Cotton fabrics/cloth
• Dual inlet
Wax patterning
technique was
utilized to pattern
microfluidic
channels on
scoured-cotton cloth
fabric and the 3D
colorimetric
microfluidic device
was made by folding
a 2D pattern
Solutions of the
respective colorimetric
reagents were pipetted
into the detection
zones. The inlet point
was immersed into the
urine. The sample
analyte was introduced
through an inlet point
to react with the
reagents
• GLU
• Nitrite
• Protein
The easy to pattern,
inexpensive and
environmentally
friendly device was
stable for a week
proving useful for
applications in
underdeveloped
areas
Nilghaz
et al. (2015)
C-μPAD
Chromatography paper The hydrophobic
barriers were made
by CVD of TCS on a
chromatography
paper
A pattern was cut out
onto a reactive surface
that was glued to paper
surface and placed
inside the CD
chamber. A
colorimetric reagent
was immobilized for a
stationary and uniform
reaction through
thermal condensation
coupling method
• GLU
• Metals
More complex
detection chambers
and higher degree
of reliability
resulted from this
device by
controlling
temperature,
pattern size, and
CVD duration
Lam et al.
(2017)
(continued)