156
A. S. Cerda-Kipper and S. Hosseini
Table 7.1
(continued)
BioMEMS
platform
Main components
Fabrication strategy Mechanisms of
operation
Detected
analyte
Specifics
References
SmartBA and
SmartChol
• iPhone 5S
• BI-CMOS sensor
• 8MP camera
• Smartphone
accessory
• Minicartridge
The minicartridge
and the mini dark
box smartphone
accessory were
fabricated using a
dual-extrusion 3D
printer using black
PMMA
thermoplastic. The
minicartridge was
printed in two
separate pieces,
which were glued
together
SmartBA relied on
conversion of certain
functional groups that
emitted BL-CL in the
presence of bacterial
luciferase. SmartChol,
operated based on
coupled enzymatic
reaction which
generated BL-CL in the
presence of
luminol−H
2 O
2
−HRP.
In both cases, the signal
was recorded by smart
phone
Cholesterol
and BA
SmartBA and
SmartChol could be
considered as the
pioneer devices in
the integration
BL-CL detection and
smartphones for
POC analysis
Roda et al. (2014)
Horseradish peroxidase (HRP); Total Bile Acid Smartphone-Based Assay (SmartBA); Total Cholesterol Smartphone-Based Assay (SmartChol)