20 Sleep-Related Modulations of Heart Rate Variability…
325
Funding This study was supported by the German-Israeli Foundation (GIF) Grants I-1298415.13/2015 and I-1372-303.7/2016 and the German National Cohort study (www.nationalekohorte.de) funded by the Federal Ministry of Education and Research (BMBF) and the
Helmholtz Association. TP was partially supported by a Russian Federation Government Grant
No. 075-15-2019-1885.
References
1. S. Akselrod, D. Gordon, F.A. Ubel, D.C. Shannon, A.C. Bargerm, R.J. Cohen, Power spectrum
analysis of heart rate fluctuations: A quantitative probe of beat-to-beat cardiovascular control.
Science 213, 220–222 (1981)
2. M. Angelova, C. Karmakar, Y. Zhu, S.P.A. Drummond, J. Ellis, Automated method for detecting
acute insomnia using multi-night actigraphy data. IEEE Access 8, 74413–74422 (2020). https://
doi.org/10.1109/access.2020.2988722
3. R. Bartsch, J.W. Kantelhardt, T. Penzel, S. Havlin, Experimental evidence for phase synchronization transitions in the human cardiorespiratory system. Phys. Rev. Lett. 98, 054102
(2007)
4. R.P. Bartsch, A.Y. Schumann, J.W. Kantelhardt, T. Penzel, P.C. Ivanov, Phase transitions in
physiologic coupling. Proc. Natl. Acad. Sci. 109, 10181–10186 (2012)
5. R.B. Berry, R. Brooks, C.E. Gamaldo, S.M. Harding, R.M. Lloyd, C.L. Marcus, B.V. Vaughn,
for the American Academy of Sleep Medicine, The AASM Manual for the Scoring of Sleep and
Associated Events: Rules, Terminology and Technical Specifications, Version 2.1 (American
Academy of Sleep Medicine, Darien, IL, 2014)
6. A. Bunde, S. Havlin, J.W. Kantelhardt, T. Penzel, J.H. Peter, K. Voigt, Correlated and
uncorrelated regions in heart-rate fluctuations during sleep. Phys. Rev. Lett. 85, 3736–3739
(2000)
7. S.M. Caples, C.L. Rosen, W.K. Shen, A.S. Gami, W. Cotts, M. Adams, P. Dorostkar, K.
Shivkumar, V.K. Somers, T.I. Morgenthaler, E.J. Stepanski, C. Iber, The scoring of cardiac
events during sleep. J. Clin. Sleep Med. 3, 147–154 (2007)
8. V.C. Cunha Sequeira, P.M. Bandeira, J.C. Moreno Azevedo, Heart rate variability in adults
with obstructive sleep apnea: a systematic review. Sleep Sci. 12(3), 214–221 (2019). https://
doi.org/10.5935/1984-0063.20190082
9. P. De Chazal, C. Heneghan, W.T. McNicholas, Multimodal detection of sleep apnoea using
electrocardiogram and oximetry signals. Phil. Trans. R. Soc. A 367, 369–389 (2009)
10. P.P. Einbrodt, Über den Einfluss der Athembewegungen auf Herzschlag und Blutdruck. Sitzungsberichte der math.-naturw. Classe der kaiserlichen Akademie der Wissenschaften. K. K. Hofund Staatsdruckerei (Wien) (Band XI, 1860), pp. 361–418
11. N.E. Fultz, G. Bonmassar, K. Setsompop, R.A. Stickgold, B.R. Rosen, J.R. Polimeni, L.D.
Lewiset, Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in
human sleep. Science 366(6465), 628–631 (2019). https://doi.org/10.1126/science.aax5440
12. M. Glos, I. Fietze, A. Blau, G. Baumann, T. Penzel, Cardiac autonomic modulation and sleepiness: physiological consequences of sleep deprivation due to 40 h of prolonged wakefulness.
Physiol. Behav. 125, 45–53 (2014)
13. A.L. Goldberger, L.A.N. Amaral, L. Glass, J.M. Hausdorff, P.C. Ivanov, R.G. Mark, J.E. Mietus,
G.B. Moody, C.K. Peng, H.E. Stanley, PhysioBank, PhysioToolkit, and PhysioNet components
of a new research resource for complex physiologic signals. Circulation 101, e215–e220 (2000)
14. C. Guilleminault, S. Connolly, R. Winkle et al., Cyclical variation of the heart rate in sleep
apnoea syndrome. Mechanisms, and usefulness of 24 h electrocardiography as a screening
technique. Lancet 8369, 126–131 (1984)
15. P.M. Holloway, M. Angelova, S. Lombardo, A. St. Clair Gibson, D. Lee, J. Ellis, Complexity
analysis of sleep and alterations with insomnia based on non-invasive techniques. J. R. Soc.
Interface 11(93), 1–8 (2014). https://doi.org/10.1098/rsif.2013.1112
325
Funding This study was supported by the German-Israeli Foundation (GIF) Grants I-1298415.13/2015 and I-1372-303.7/2016 and the German National Cohort study (www.nationalekohorte.de) funded by the Federal Ministry of Education and Research (BMBF) and the
Helmholtz Association. TP was partially supported by a Russian Federation Government Grant
No. 075-15-2019-1885.
References
1. S. Akselrod, D. Gordon, F.A. Ubel, D.C. Shannon, A.C. Bargerm, R.J. Cohen, Power spectrum
analysis of heart rate fluctuations: A quantitative probe of beat-to-beat cardiovascular control.
Science 213, 220–222 (1981)
2. M. Angelova, C. Karmakar, Y. Zhu, S.P.A. Drummond, J. Ellis, Automated method for detecting
acute insomnia using multi-night actigraphy data. IEEE Access 8, 74413–74422 (2020). https://
doi.org/10.1109/access.2020.2988722
3. R. Bartsch, J.W. Kantelhardt, T. Penzel, S. Havlin, Experimental evidence for phase synchronization transitions in the human cardiorespiratory system. Phys. Rev. Lett. 98, 054102
(2007)
4. R.P. Bartsch, A.Y. Schumann, J.W. Kantelhardt, T. Penzel, P.C. Ivanov, Phase transitions in
physiologic coupling. Proc. Natl. Acad. Sci. 109, 10181–10186 (2012)
5. R.B. Berry, R. Brooks, C.E. Gamaldo, S.M. Harding, R.M. Lloyd, C.L. Marcus, B.V. Vaughn,
for the American Academy of Sleep Medicine, The AASM Manual for the Scoring of Sleep and
Associated Events: Rules, Terminology and Technical Specifications, Version 2.1 (American
Academy of Sleep Medicine, Darien, IL, 2014)
6. A. Bunde, S. Havlin, J.W. Kantelhardt, T. Penzel, J.H. Peter, K. Voigt, Correlated and
uncorrelated regions in heart-rate fluctuations during sleep. Phys. Rev. Lett. 85, 3736–3739
(2000)
7. S.M. Caples, C.L. Rosen, W.K. Shen, A.S. Gami, W. Cotts, M. Adams, P. Dorostkar, K.
Shivkumar, V.K. Somers, T.I. Morgenthaler, E.J. Stepanski, C. Iber, The scoring of cardiac
events during sleep. J. Clin. Sleep Med. 3, 147–154 (2007)
8. V.C. Cunha Sequeira, P.M. Bandeira, J.C. Moreno Azevedo, Heart rate variability in adults
with obstructive sleep apnea: a systematic review. Sleep Sci. 12(3), 214–221 (2019). https://
doi.org/10.5935/1984-0063.20190082
9. P. De Chazal, C. Heneghan, W.T. McNicholas, Multimodal detection of sleep apnoea using
electrocardiogram and oximetry signals. Phil. Trans. R. Soc. A 367, 369–389 (2009)
10. P.P. Einbrodt, Über den Einfluss der Athembewegungen auf Herzschlag und Blutdruck. Sitzungsberichte der math.-naturw. Classe der kaiserlichen Akademie der Wissenschaften. K. K. Hofund Staatsdruckerei (Wien) (Band XI, 1860), pp. 361–418
11. N.E. Fultz, G. Bonmassar, K. Setsompop, R.A. Stickgold, B.R. Rosen, J.R. Polimeni, L.D.
Lewiset, Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in
human sleep. Science 366(6465), 628–631 (2019). https://doi.org/10.1126/science.aax5440
12. M. Glos, I. Fietze, A. Blau, G. Baumann, T. Penzel, Cardiac autonomic modulation and sleepiness: physiological consequences of sleep deprivation due to 40 h of prolonged wakefulness.
Physiol. Behav. 125, 45–53 (2014)
13. A.L. Goldberger, L.A.N. Amaral, L. Glass, J.M. Hausdorff, P.C. Ivanov, R.G. Mark, J.E. Mietus,
G.B. Moody, C.K. Peng, H.E. Stanley, PhysioBank, PhysioToolkit, and PhysioNet components
of a new research resource for complex physiologic signals. Circulation 101, e215–e220 (2000)
14. C. Guilleminault, S. Connolly, R. Winkle et al., Cyclical variation of the heart rate in sleep
apnoea syndrome. Mechanisms, and usefulness of 24 h electrocardiography as a screening
technique. Lancet 8369, 126–131 (1984)
15. P.M. Holloway, M. Angelova, S. Lombardo, A. St. Clair Gibson, D. Lee, J. Ellis, Complexity
analysis of sleep and alterations with insomnia based on non-invasive techniques. J. R. Soc.
Interface 11(93), 1–8 (2014). https://doi.org/10.1098/rsif.2013.1112