Metallic Nanoparticles for Biomedical Applications
33
Fig. 1 a Schematic diagram used to represent nucleation and growth process in the formation of
MNPs according to LaMer’s concept. The concentration of solute and the number of particles over
time are described. Republished with permission of the Royal Society of Chemistry, from Ref. [10].
b Schematic illustration of Au NPs formation using NaBH 4 reduction. It consists of reduction and
nucleation within 200 ms, accompanied by coalescence of nuclei into bigger particles. Reprinted
with permission from [11] Copyright (2010) American Chemical Society
properties. Due to these features, Au NPs are useful in applications like biomedical imaging, therapeutics, sensing, catalysis, analytical science, medical diagnosis,
and drug delivery [19–26]. Based on size and shape, the colour of the yellow
gold precursor turns red, violet, blue, green, and yellow [27]. Figure 2 depicts the
colour dependency of Au NPs on shape and size for commonly employed particles
in biomedical applications. MNPs have some exciting features which make them
suitable in various fields such as thermal, electronics, photonics, catalysis, optoelectronics, and biomedical. Among these features, interesting behaviour is surface
plasmon resonance, which happens when the size of the particle becomes comparable with the wavelength of incident light [28]. Usually, MNPs in size range of
10–100 nm possess variable surface plasmonic resonance in the visible region with
33
Fig. 1 a Schematic diagram used to represent nucleation and growth process in the formation of
MNPs according to LaMer’s concept. The concentration of solute and the number of particles over
time are described. Republished with permission of the Royal Society of Chemistry, from Ref. [10].
b Schematic illustration of Au NPs formation using NaBH 4 reduction. It consists of reduction and
nucleation within 200 ms, accompanied by coalescence of nuclei into bigger particles. Reprinted
with permission from [11] Copyright (2010) American Chemical Society
properties. Due to these features, Au NPs are useful in applications like biomedical imaging, therapeutics, sensing, catalysis, analytical science, medical diagnosis,
and drug delivery [19–26]. Based on size and shape, the colour of the yellow
gold precursor turns red, violet, blue, green, and yellow [27]. Figure 2 depicts the
colour dependency of Au NPs on shape and size for commonly employed particles
in biomedical applications. MNPs have some exciting features which make them
suitable in various fields such as thermal, electronics, photonics, catalysis, optoelectronics, and biomedical. Among these features, interesting behaviour is surface
plasmon resonance, which happens when the size of the particle becomes comparable with the wavelength of incident light [28]. Usually, MNPs in size range of
10–100 nm possess variable surface plasmonic resonance in the visible region with