Nanomaterials for Medical Imaging …
399
252. Unger E, Shen D, Fritz T, Kulik B, Lund P, Wu GL, Yellowhair D, Ramaswami R, Matsunaga T
(1994) Gas-filled lipid bilayers as ultrasound contrast agents. Invest Radiol 29(Suppl 2):S134–
136. https://doi.org/10.1097/00004424-199406001-00044
253. Zhao YZ, Du LN, Lu CT, Jin YG, Ge SP (2013) Potential and problems in ultrasoundresponsive drug delivery systems. Int J Nanomed 8:1621–1633. https://doi.org/10.2147/IJN.
S43589
254. Alheshibri M, Craig VSJ (2019) Armoured nanobubbles; ultrasound contrast agents under
pressure. J Coll Interface Sci 537:123–131. https://doi.org/10.1016/j.jcis.2018.10.108
255. Yasuda K, Matsushima H, Asakura Y (2019) Generation and reduction of bulk nanobubbles by
ultrasonic irradiation. Chem Eng Sci 195:455–461. https://doi.org/10.1016/j.ces.2018.09.044
256. Kalus M-R, Reimer V, Barcikowski S, Gökce B (2019) Discrimination of effects leading to
gas formation during pulsed laser ablation in liquids. Appl Surf Sci 465:1096–1102. https://
doi.org/10.1016/j.apsusc.2018.09.224
257. Stride E, Edirisinghe M (2008) Novel microbubble preparation technologies. Soft Matter
4(12):2350. https://doi.org/10.1039/b809517p
258. Khan MS, Hwang J, Lee K, Choi Y, Kim K, Koo HJ, Hong JW, Choi J (2018) Oxygencarrying micro/nanobubbles: composition, synthesis techniques and potential prospects in
photo-triggered theranostics. Molecules 23(9). https://doi.org/10.3390/molecules23092210
259. Alheshibri M, Qian J, Jehannin M, Craig VS (2016) A history of nanobubbles. Langmuir:
ACS J Surf Coll 32(43):11086–11100. https://doi.org/10.1021/acs.langmuir.6b02489
260. Johnson BD, Cooke RC (1981) Generation of stabilized microbubbles in seawater. Science
213(4504):209–211. https://doi.org/10.1126/science.213.4504.209
261. Kikuchi K, Ioka A, Oku T, Tanaka Y, Saihara Y, Ogumi Z (2009) Concentration determination
of oxygen nanobubbles in electrolyzed water. J Coll Interface Sci 329(2):306–309. https://
doi.org/10.1016/j.jcis.2008.10.009
262. Kikuchi K, Nagata S, Tanaka Y, Saihara Y, Ogumi Z (2007) Characteristics of hydrogen
nanobubbles in solutions obtained with water electrolysis. J Electroanal Chem 600(2):303–
310. https://doi.org/10.1016/j.jelechem.2006.10.005
263. Ohgaki K, Khanh NQ, Joden Y, Tsuji A, Nakagawa T (2010) Physicochemical approach to
nanobubble solutions. Chem Eng Sci 65(3):1296–1300. https://doi.org/10.1016/j.ces.2009.
10.003
264. Cai WB, Yang HL, Zhang J, Yin JK, Yang YL, Yuan LJ, Zhang L, Duan YY (2015) The
optimized fabrication of nanobubbles as ultrasound contrast agents for tumor imaging. Sci
Rep 5:13725. https://doi.org/10.1038/srep13725
265. Pan TL, Wang PW, Al-Suwayeh SA, Huang YJ, Fang JY (2012) Toxicological effects of
cationic nanobubbles on the liver and kidneys: biomarkers for predicting the risk. Food Chem
Toxicol 50(11):3892–3901. https://doi.org/10.1016/j.fct.2012.07.005
266. Mai L, Yao A, Li J, Wei Q, Yuchi M, He X, Ding M, Zhou Q (2013) Cyanine 5.5 conjugated
nanobubbles as a tumor selective contrast agent for dual ultrasound-fluorescence imaging in
a mouse model. PloS One 8(4):e61224. https://doi.org/10.1371/journal.pone.0061224
267. Huang HY, Hu SH, Hung SY, Chiang CS, Liu HL, Chiu TL, Lai HY, Chen YY, Chen SY
(2013) SPIO nanoparticle-stabilized PAA-F127 thermosensitive nanobubbles with MR/US
dual-modality imaging and HIFU-triggered drug release for magnetically guided in vivo
tumor therapy. J Controll Release: Off J Controll Release Soc 172(1):118–127. https://doi.
org/10.1016/j.jconrel.2013.07.029
268. Huang HY, Liu HL, Hsu PH, Chiang CS, Tsai CH, Chi HS, Chen SY, Chen YY (2015) A
multitheragnostic nanobubble system to induce blood-brain barrier disruption with magnetically guided focused ultrasound. Adv Mater 27(4):655–661. https://doi.org/10.1002/adma.
201403889
269. Fan X, Wang L, Guo Y, Tu Z, Li L, Tong H, Xu Y, Li R, Fang K (2015) Ultrasonic nanobubbles carrying anti-PSMA nanobody: construction and application in prostate cancer-targeted
imaging. PLoS One 10(6):e0127419. https://doi.org/10.1371/journal.pone.0127419
270. Peyman SA, McLaughlan JR, Abou-Saleh RH, Marston G, Johnson BR, Freear S, Coletta
PL, Markham AF, Evans SD (2016) On-chip preparation of nanoscale contrast agents towards
399
252. Unger E, Shen D, Fritz T, Kulik B, Lund P, Wu GL, Yellowhair D, Ramaswami R, Matsunaga T
(1994) Gas-filled lipid bilayers as ultrasound contrast agents. Invest Radiol 29(Suppl 2):S134–
136. https://doi.org/10.1097/00004424-199406001-00044
253. Zhao YZ, Du LN, Lu CT, Jin YG, Ge SP (2013) Potential and problems in ultrasoundresponsive drug delivery systems. Int J Nanomed 8:1621–1633. https://doi.org/10.2147/IJN.
S43589
254. Alheshibri M, Craig VSJ (2019) Armoured nanobubbles; ultrasound contrast agents under
pressure. J Coll Interface Sci 537:123–131. https://doi.org/10.1016/j.jcis.2018.10.108
255. Yasuda K, Matsushima H, Asakura Y (2019) Generation and reduction of bulk nanobubbles by
ultrasonic irradiation. Chem Eng Sci 195:455–461. https://doi.org/10.1016/j.ces.2018.09.044
256. Kalus M-R, Reimer V, Barcikowski S, Gökce B (2019) Discrimination of effects leading to
gas formation during pulsed laser ablation in liquids. Appl Surf Sci 465:1096–1102. https://
doi.org/10.1016/j.apsusc.2018.09.224
257. Stride E, Edirisinghe M (2008) Novel microbubble preparation technologies. Soft Matter
4(12):2350. https://doi.org/10.1039/b809517p
258. Khan MS, Hwang J, Lee K, Choi Y, Kim K, Koo HJ, Hong JW, Choi J (2018) Oxygencarrying micro/nanobubbles: composition, synthesis techniques and potential prospects in
photo-triggered theranostics. Molecules 23(9). https://doi.org/10.3390/molecules23092210
259. Alheshibri M, Qian J, Jehannin M, Craig VS (2016) A history of nanobubbles. Langmuir:
ACS J Surf Coll 32(43):11086–11100. https://doi.org/10.1021/acs.langmuir.6b02489
260. Johnson BD, Cooke RC (1981) Generation of stabilized microbubbles in seawater. Science
213(4504):209–211. https://doi.org/10.1126/science.213.4504.209
261. Kikuchi K, Ioka A, Oku T, Tanaka Y, Saihara Y, Ogumi Z (2009) Concentration determination
of oxygen nanobubbles in electrolyzed water. J Coll Interface Sci 329(2):306–309. https://
doi.org/10.1016/j.jcis.2008.10.009
262. Kikuchi K, Nagata S, Tanaka Y, Saihara Y, Ogumi Z (2007) Characteristics of hydrogen
nanobubbles in solutions obtained with water electrolysis. J Electroanal Chem 600(2):303–
310. https://doi.org/10.1016/j.jelechem.2006.10.005
263. Ohgaki K, Khanh NQ, Joden Y, Tsuji A, Nakagawa T (2010) Physicochemical approach to
nanobubble solutions. Chem Eng Sci 65(3):1296–1300. https://doi.org/10.1016/j.ces.2009.
10.003
264. Cai WB, Yang HL, Zhang J, Yin JK, Yang YL, Yuan LJ, Zhang L, Duan YY (2015) The
optimized fabrication of nanobubbles as ultrasound contrast agents for tumor imaging. Sci
Rep 5:13725. https://doi.org/10.1038/srep13725
265. Pan TL, Wang PW, Al-Suwayeh SA, Huang YJ, Fang JY (2012) Toxicological effects of
cationic nanobubbles on the liver and kidneys: biomarkers for predicting the risk. Food Chem
Toxicol 50(11):3892–3901. https://doi.org/10.1016/j.fct.2012.07.005
266. Mai L, Yao A, Li J, Wei Q, Yuchi M, He X, Ding M, Zhou Q (2013) Cyanine 5.5 conjugated
nanobubbles as a tumor selective contrast agent for dual ultrasound-fluorescence imaging in
a mouse model. PloS One 8(4):e61224. https://doi.org/10.1371/journal.pone.0061224
267. Huang HY, Hu SH, Hung SY, Chiang CS, Liu HL, Chiu TL, Lai HY, Chen YY, Chen SY
(2013) SPIO nanoparticle-stabilized PAA-F127 thermosensitive nanobubbles with MR/US
dual-modality imaging and HIFU-triggered drug release for magnetically guided in vivo
tumor therapy. J Controll Release: Off J Controll Release Soc 172(1):118–127. https://doi.
org/10.1016/j.jconrel.2013.07.029
268. Huang HY, Liu HL, Hsu PH, Chiang CS, Tsai CH, Chi HS, Chen SY, Chen YY (2015) A
multitheragnostic nanobubble system to induce blood-brain barrier disruption with magnetically guided focused ultrasound. Adv Mater 27(4):655–661. https://doi.org/10.1002/adma.
201403889
269. Fan X, Wang L, Guo Y, Tu Z, Li L, Tong H, Xu Y, Li R, Fang K (2015) Ultrasonic nanobubbles carrying anti-PSMA nanobody: construction and application in prostate cancer-targeted
imaging. PLoS One 10(6):e0127419. https://doi.org/10.1371/journal.pone.0127419
270. Peyman SA, McLaughlan JR, Abou-Saleh RH, Marston G, Johnson BR, Freear S, Coletta
PL, Markham AF, Evans SD (2016) On-chip preparation of nanoscale contrast agents towards