Fig. 1.1 The structure of genes in the euchromatin of
Neurospora crassa. (a) Top: Structure of a typical
euchromatic gene in Neurospora prior to transcription
initiation. The nucleosome-free region (NFR) is cleared
by ATP-dependent chromatin remodelers, allowing
transcription factors and RNA polymerase II (RNAPII)
to bind to the accessible DNA; nucleosomes near the
transcription start site (TSS) are enriched for acetylation
and the histone variant H2A.Z. Bottom: Upon recruitment of RNAPII, transcription is initiated, and the
repressive H3K36me2 is converted to H3K36me3 by
RNAPII-associated SET-2/KMT3 or the RNAPII1 Chromatin Structure and Function in Neurospora crassa
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