130
Ar
CO 2 H
O
+
O
O
R
10 mol% AgNO 3
2 equiv K 2 S 2 O 8
DMSO /H 2 O, rt
O
O
R
O
Ar
Ar
O
O
O
R
Ar
CO 2 H
O
- CO 2
O
O
R
Ar
O
O
O
R
O
Ar
Ar
O
Ar
O
Ar
O
O
O
R
O
Ar
Ar
O
Scheme 4.47 Acylation of coumarins
N
O
R
R
CO 2 H
O
+
CH 3 CN/H 2 O, rt
N
O
R
Ar
Ar
R
O
N
O
Ar
O
N
O
10 mol% AgNO 3
1 equiv K 2 S 2 O 8
H 2 O, 50 °C
Ar
CO 2 H
O
+
2 mol% AgNO 3
1 equiv K 2 S 2 O 8
Scheme 4.48 Decarboxylative acylation of acrylamides
4.4 Oxidative Radical C-X Couplings
Based on the concept of oxidative coupling to construct various C-C bonds, oxidative radical coupling toward generation of various C-X (O, S, N, P, etc.) bonds is
possible.
W. Liu