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D. Cabrera DeBuc et al.
Fig. 2.4 OCT images of the retina for a healthy and pathologic human eye. a Image of the retina
of a normal healthy subject. Note that the fovea has a characteristic depression with thinning of
the retina corresponding to its normal anatomy. b OCT image from a subject with diabetic macular
edema. Note the thickening of the macula with several sizeable hypo-reflective cystoid spaces in
the central region. The OCT signal strength is represented in false color using the normally visible
spectrum scale, and low backscatter appears blue-black
several large hyporeflective cystoid spaces in the fovea. When comparing the image
of the pathologic subject with the one obtained in the normal healthy subject, the
importance of quantifying the structural changes of retinal features and pathologies
is more than evident.
In the retina, the vitreoretinal interface is demarcated by the reflections from
the surface of the retina. The RPE and choriocapillaris layer (ChCap) is visualized
as a highly reflective red layer and represents the posterior boundary of the retina.
Below the choriocapillaris weakly scattered light returns from the choroid and sclera
because of attenuation of the signal after passing through the neurosensory retina,
RPE, and ChCap. The outer segments of the rods and cones appear as a dark layer
D. Cabrera DeBuc et al.
Fig. 2.4 OCT images of the retina for a healthy and pathologic human eye. a Image of the retina
of a normal healthy subject. Note that the fovea has a characteristic depression with thinning of
the retina corresponding to its normal anatomy. b OCT image from a subject with diabetic macular
edema. Note the thickening of the macula with several sizeable hypo-reflective cystoid spaces in
the central region. The OCT signal strength is represented in false color using the normally visible
spectrum scale, and low backscatter appears blue-black
several large hyporeflective cystoid spaces in the fovea. When comparing the image
of the pathologic subject with the one obtained in the normal healthy subject, the
importance of quantifying the structural changes of retinal features and pathologies
is more than evident.
In the retina, the vitreoretinal interface is demarcated by the reflections from
the surface of the retina. The RPE and choriocapillaris layer (ChCap) is visualized
as a highly reflective red layer and represents the posterior boundary of the retina.
Below the choriocapillaris weakly scattered light returns from the choroid and sclera
because of attenuation of the signal after passing through the neurosensory retina,
RPE, and ChCap. The outer segments of the rods and cones appear as a dark layer