155, 169, 170, 176, 177, 180–183, 186,
187, 211, 214, 232, 243, 244, 249–251,
254, 255, 257, 261, 262, 264–266, 270,
281–283, 285, 295–298, 303–308, 327,
328, 330, 348, 349, 367, 371
Retinal artery occlusion, 13, 170, 171,
180–182, 184, 185
Retinal atrophy, 132
Retinal diabetic neurodegeneration, 133
Retinal hemorrhage, 16, 17, 23
Retinal Nerve Fiber Layer (RNFL), 11, 13, 33,
35, 132, 133, 138, 140, 142–151,
169–171, 175, 176, 178–181, 183, 186,
260, 261, 284, 286, 292, 294, 297, 302,
303, 306, 307, 329, 330
Retinal Pigment Epithelium (RPE), 6, 16, 18,
20, 21, 23, 30, 33–35, 107, 133, 138,
140, 141, 151, 152, 155, 171, 177–183,
186, 194–200, 211, 216, 217, 228,
243–245, 248, 250, 251, 254, 258–261,
267, 270, 283–286, 289, 292–297, 299,
301–308, 320–332, 335, 336, 338, 339,
347–349, 371
Retinal vasculitis, 13
Retinal vein occlusion, 13, 17, 19, 368
Retinitis pigmentosa, 133
Retinoschisis, 10, 11
Rim/disc area ratio (R/D area ratio), 171, 176,
177, 179, 180
RPE/Bruch’s complex, 5
S
Scanning Laser Ophthalmoscopy (SLO), 32
Sclera, 1, 10, 34, 182, 211–213, 217, 235, 325
Sensitivity (SEN), 271, 273
Serous retinal detachment, 16, 18, 19
Shape prior, 105, 106, 109, 110, 113, 114, 116,
118, 120, 121
Shrinkage function, 55, 58, 61, 63
Signal Strength (SS), 134, 353
Signal-to-Noise Ratio (SNR), 29, 51, 65, 73,
76, 78, 81, 89, 91, 97, 135, 284, 294,
346
Sparse representation, 52, 74, 79, 90, 93–95,
97, 215
Specificity (SPE), 271, 273
Speckle noise reduction, 55
Spectral Domain OCT (SD-OCT), 29, 30, 137,
138, 141, 143, 151, 153–155, 175,
194–196, 199, 201–203, 211, 224, 233,
236, 243, 244, 252, 259–261, 265, 266,
270, 274, 283–286, 288, 294–298,
303–308, 311, 315, 317, 319, 320,
323–327, 329, 330, 334, 339, 345, 346,
358
Spherical alignment, 227–229
Spherical Equivalent (SE), 150, 176, 180
SPIHT, 95–98
Stargardt’s disease, 133
Statistical model, 44, 48, 106
S/t cut, 347
Stromal-luminal ratio, 211, 212, 232, 238
Structural similarity (SSIM), 213, 217, 238
Subdictionaries, 76–78
Subretinal fluid, 345, 347, 358, 368
Sub-RPE Slab
Summed-Voxel Projection (SVP), 285, 286,
295, 296, 298, 299, 301–304, 306–308,
320, 321, 323, 325, 327–339
Support Vector Machine (SVM), 44, 46, 47,
119, 195, 198–200, 204
Swept Source OCT (SS-OCT), 29–31
Symptomatic Exudates Associated
Derangement (SEAD), 54, 64, 65,
345–351, 356–362
T
Tensor voting, 213, 216, 218, 238
Tetrahedral meshing, 372
Thickness measurements, 13, 132, 144, 148,
170, 213
Thin plate spline, 349
Time Domain OCT (TD-OCT), 28, 29, 141,
150, 153–155
Topcon, 13, 49, 50, 54, 56, 65, 67, 171, 175,
176, 181, 182, 245, 252, 270
Transform histogram shaping, 49, 50
Transform model, 55
Transverse resolution, 29, 32, 171, 176, 214
True Positive Volume Fraction (TPVF),
355–357, 375–377
T-test, 172, 177–179, 262, 270, 271, 273
Two-sided rayleigh noise, 61, 63, 66
U
Unsigned Border Error (UBE), 201, 202
Uvea, 1
Uveitis, 137, 244
V
Variational inference, 110
Vascular tunic, 1
Vessel silhouettes, 261, 262, 266, 270, 272
Visible light OCT (Vis-OCT), 32
Vitreomacular adhesion, 5, 6
Vitreomacular interface, 5, 10, 11
384
Index
187, 211, 214, 232, 243, 244, 249–251,
254, 255, 257, 261, 262, 264–266, 270,
281–283, 285, 295–298, 303–308, 327,
328, 330, 348, 349, 367, 371
Retinal artery occlusion, 13, 170, 171,
180–182, 184, 185
Retinal atrophy, 132
Retinal diabetic neurodegeneration, 133
Retinal hemorrhage, 16, 17, 23
Retinal Nerve Fiber Layer (RNFL), 11, 13, 33,
35, 132, 133, 138, 140, 142–151,
169–171, 175, 176, 178–181, 183, 186,
260, 261, 284, 286, 292, 294, 297, 302,
303, 306, 307, 329, 330
Retinal Pigment Epithelium (RPE), 6, 16, 18,
20, 21, 23, 30, 33–35, 107, 133, 138,
140, 141, 151, 152, 155, 171, 177–183,
186, 194–200, 211, 216, 217, 228,
243–245, 248, 250, 251, 254, 258–261,
267, 270, 283–286, 289, 292–297, 299,
301–308, 320–332, 335, 336, 338, 339,
347–349, 371
Retinal vasculitis, 13
Retinal vein occlusion, 13, 17, 19, 368
Retinitis pigmentosa, 133
Retinoschisis, 10, 11
Rim/disc area ratio (R/D area ratio), 171, 176,
177, 179, 180
RPE/Bruch’s complex, 5
S
Scanning Laser Ophthalmoscopy (SLO), 32
Sclera, 1, 10, 34, 182, 211–213, 217, 235, 325
Sensitivity (SEN), 271, 273
Serous retinal detachment, 16, 18, 19
Shape prior, 105, 106, 109, 110, 113, 114, 116,
118, 120, 121
Shrinkage function, 55, 58, 61, 63
Signal Strength (SS), 134, 353
Signal-to-Noise Ratio (SNR), 29, 51, 65, 73,
76, 78, 81, 89, 91, 97, 135, 284, 294,
346
Sparse representation, 52, 74, 79, 90, 93–95,
97, 215
Specificity (SPE), 271, 273
Speckle noise reduction, 55
Spectral Domain OCT (SD-OCT), 29, 30, 137,
138, 141, 143, 151, 153–155, 175,
194–196, 199, 201–203, 211, 224, 233,
236, 243, 244, 252, 259–261, 265, 266,
270, 274, 283–286, 288, 294–298,
303–308, 311, 315, 317, 319, 320,
323–327, 329, 330, 334, 339, 345, 346,
358
Spherical alignment, 227–229
Spherical Equivalent (SE), 150, 176, 180
SPIHT, 95–98
Stargardt’s disease, 133
Statistical model, 44, 48, 106
S/t cut, 347
Stromal-luminal ratio, 211, 212, 232, 238
Structural similarity (SSIM), 213, 217, 238
Subdictionaries, 76–78
Subretinal fluid, 345, 347, 358, 368
Sub-RPE Slab
Summed-Voxel Projection (SVP), 285, 286,
295, 296, 298, 299, 301–304, 306–308,
320, 321, 323, 325, 327–339
Support Vector Machine (SVM), 44, 46, 47,
119, 195, 198–200, 204
Swept Source OCT (SS-OCT), 29–31
Symptomatic Exudates Associated
Derangement (SEAD), 54, 64, 65,
345–351, 356–362
T
Tensor voting, 213, 216, 218, 238
Tetrahedral meshing, 372
Thickness measurements, 13, 132, 144, 148,
170, 213
Thin plate spline, 349
Time Domain OCT (TD-OCT), 28, 29, 141,
150, 153–155
Topcon, 13, 49, 50, 54, 56, 65, 67, 171, 175,
176, 181, 182, 245, 252, 270
Transform histogram shaping, 49, 50
Transform model, 55
Transverse resolution, 29, 32, 171, 176, 214
True Positive Volume Fraction (TPVF),
355–357, 375–377
T-test, 172, 177–179, 262, 270, 271, 273
Two-sided rayleigh noise, 61, 63, 66
U
Unsigned Border Error (UBE), 201, 202
Uvea, 1
Uveitis, 137, 244
V
Variational inference, 110
Vascular tunic, 1
Vessel silhouettes, 261, 262, 266, 270, 272
Visible light OCT (Vis-OCT), 32
Vitreomacular adhesion, 5, 6
Vitreomacular interface, 5, 10, 11
384
Index