370
F. Shi et al.
Parameters Prediction by Curve
fitting
Image N-1
Preprocessing
Parameter
Training
Meshing
CNV
Growth
Model
Image 1
Preprocessing
Parameter
Training
Meshing
CNV
Growth
Model
Image N
Preprocessing
Validation
Predicted
Image
Image N-1
Preprocessing
CNV
Growth
Model
Meshing
Fig. 13.2 Framework of the proposed method
Treatment
group
Month
0
1
2
3
4
5
6
7
8
9
10
11
12
Reference
group
CORE TREATMENT PHASE
EXTENDED TREATMENTPHASE
Fig. 13.3 Illustration of the injection on treatment group and reference group. The red arrows
represent treatment of intravitreal injections, the black arrows represent the injection of condolences
agent and the blue arrows represent the assessment time