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38. I. Gorczynska, V.J. Srinivasan, L.N. Vuong, R.W.S. Chen, J.J. Liu, E. Reichel, M. Wojtkowski,
J.S. Schuman, J.S. Duker, J.G. Fujimoto, Projection OCT fundus imaging for visualizing outer
retinal pathology in non-exudative age-related macular degeneration. Br. J. Ophthalmol. 93(5),
603–609 (2009)
39. R. Klein, M.D. Davis, Y.L. Magli, P. Segal et al., The Wisconsin age-related maculopathy
grading system. Ophthalmology 98, 1128–1134 (1991)
40. R.T. Smith, J.K. Chan, T. Nagasaki et al., A method of drusen measurement based on reconstruction of fundus background reflectance. Br. J. Ophthalmol. 89, 87–91 (2005)
41. D.S. Shin, N.B. Javornik, J.W. Berger, Computer-assisted, interactive fundus image processing
for macular drusen quantitation. Ophthalmology 106, 1119–1125 (1999)
42. S.J. Chiu, X.T. Li, P. Nicholas, C.A. Toth, J.A. Izatt, S. Farsiu, Automatic segmentation of seven
retinal layers in SDOCT images congruent with expert manual segmentation. Opt. Express
18(18), 19413–19428 (2010)
43. S. Lu, C.Y.L. Cheung, J. Liu, J.H. Lim, C.K.S. Leung, T.Y. Wong, Automated layer segmentation of optical coherence tomography images. IEEE Trans. Biomed. Eng. 57(10), 2605–2608
(2010)
44. M.K. Garvin, M.D. Abramoff, X. Wu, S.R. Russell, T.L. Burns, M. Sonka, Automated 3D intraretinal layer segmentation of macular spectral-domain optical coherence tomography
images. IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009)
45. A. Bindewald, A.C. Bird, S.S. Dandekar, J. Dolar-Szczasny, J. Dreyhaupt, F.W. Fitzke, W.
Einbock, F.G. Holz, J.J. Jorzik, C. Keilhauer, N. Lois, J. Mlynski, D. Pauleikhoff, G. Staurenghi,
S. Wolf, Classification of fundus auto-fuorescence patterns in early age-related macular disease.
Invest. Ophthalmol. Vis. Sci. 46(9), 3309–3314 (2005)
46. S. Schmitz-Valckenberg, C.K. Brinkmann, F. Alten, P. Herrmann, N.K. Stratmann, A.P. Gobel,
M. Fleckenstein, M. Diller, G.J. Jaffe, F.G. Holz, Semiautomated image processing method for
identification and quantification of geographic atrophy in age-related macular degeneration.
Invest. Ophthalmol. Vis. Sci. 52(10), 7640–7646 (2011)
47. A. Deckert, S. Schmitz-Valckenberg, J. Jorzik, A. Bindewald, F.G. Holz, U. Mansmann, Automated analysis of digital fundus autofluorescence images of geographic atrophy in advanced
age-related macular degeneration using confocal scanning laser ophthalmoscopy (cSLO). BMC
Ophthalmol. 5, 1–8 (2005)
48. N. Lee, A.F. Laine, I. Barbazetto, M. Busuoic, R. Smith, Level set segmentation of geographic
atrophy in macular autofluorescence images. Invest. Ophthalmol. Vis. Sci. 47(10) (2006)
49. N. Lee, A.F.Laine, R.T. Smith, A hybrid segmentation approach for geographic atrophy in fundus auto-fluorescence images for diagnosis of age-related macular degeneration, in Proceeding
of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology
Society, 4965–4968 2007
50. N. Lee, A.F. Laine, R.T. Smith, Interactive segmentation for geographic atrophy in retinal
fundus images, in the 42nd Asilomar Conference on Signals, Systems and Computers, vol. 42,
pp. 655–658 2008
51. R.G. Sayegh, C. Simader, U. Schechy, A. Montuoro, C. Kiss, S. Sacu, D.P. Kreil, C. Prunte,
U. Schmidt-Erfurth, A systematic comparison of spectral-domain optical coherence tomography and fundus autofluorescence in patients with geographic atrophy. Ophthalmology 118(9),
1844–1851 (2011)
52. S.J. Chiu, J.A. Izatt, R.V. O’Connell, K.P. Winter, C.A. Toth, S. Farsiu, Validated automatic
segmentation of AMD pathology including drusen and geographic atrophy in SDOCT images.
Invest. Ophthalmol. Vis. Sci. 53(1), 53–61 (2012)
53. C. Schütze, C. Ahlers, S. Sacu, G. Mylonas, R. Sayegh, I. Golbaz, G. Matt, G. Stock, U.
Schmidt-Erfurth, Performance of OCT segmentation procedures to assess morphology and
extension in geographic atrophy. Acta. Ophthalmol. 89(3), 235–240 (2011)
Q. Chen et al.
37. M. Stopa, B.A. Bower, E. Davies, J.A. Izatt, C.A. Toth, Correlation of pathologic features in
spectral domain optical coherence tomography with conventional retinal studies. Retina 28(2),
298–308 (2008)
38. I. Gorczynska, V.J. Srinivasan, L.N. Vuong, R.W.S. Chen, J.J. Liu, E. Reichel, M. Wojtkowski,
J.S. Schuman, J.S. Duker, J.G. Fujimoto, Projection OCT fundus imaging for visualizing outer
retinal pathology in non-exudative age-related macular degeneration. Br. J. Ophthalmol. 93(5),
603–609 (2009)
39. R. Klein, M.D. Davis, Y.L. Magli, P. Segal et al., The Wisconsin age-related maculopathy
grading system. Ophthalmology 98, 1128–1134 (1991)
40. R.T. Smith, J.K. Chan, T. Nagasaki et al., A method of drusen measurement based on reconstruction of fundus background reflectance. Br. J. Ophthalmol. 89, 87–91 (2005)
41. D.S. Shin, N.B. Javornik, J.W. Berger, Computer-assisted, interactive fundus image processing
for macular drusen quantitation. Ophthalmology 106, 1119–1125 (1999)
42. S.J. Chiu, X.T. Li, P. Nicholas, C.A. Toth, J.A. Izatt, S. Farsiu, Automatic segmentation of seven
retinal layers in SDOCT images congruent with expert manual segmentation. Opt. Express
18(18), 19413–19428 (2010)
43. S. Lu, C.Y.L. Cheung, J. Liu, J.H. Lim, C.K.S. Leung, T.Y. Wong, Automated layer segmentation of optical coherence tomography images. IEEE Trans. Biomed. Eng. 57(10), 2605–2608
(2010)
44. M.K. Garvin, M.D. Abramoff, X. Wu, S.R. Russell, T.L. Burns, M. Sonka, Automated 3D intraretinal layer segmentation of macular spectral-domain optical coherence tomography
images. IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009)
45. A. Bindewald, A.C. Bird, S.S. Dandekar, J. Dolar-Szczasny, J. Dreyhaupt, F.W. Fitzke, W.
Einbock, F.G. Holz, J.J. Jorzik, C. Keilhauer, N. Lois, J. Mlynski, D. Pauleikhoff, G. Staurenghi,
S. Wolf, Classification of fundus auto-fuorescence patterns in early age-related macular disease.
Invest. Ophthalmol. Vis. Sci. 46(9), 3309–3314 (2005)
46. S. Schmitz-Valckenberg, C.K. Brinkmann, F. Alten, P. Herrmann, N.K. Stratmann, A.P. Gobel,
M. Fleckenstein, M. Diller, G.J. Jaffe, F.G. Holz, Semiautomated image processing method for
identification and quantification of geographic atrophy in age-related macular degeneration.
Invest. Ophthalmol. Vis. Sci. 52(10), 7640–7646 (2011)
47. A. Deckert, S. Schmitz-Valckenberg, J. Jorzik, A. Bindewald, F.G. Holz, U. Mansmann, Automated analysis of digital fundus autofluorescence images of geographic atrophy in advanced
age-related macular degeneration using confocal scanning laser ophthalmoscopy (cSLO). BMC
Ophthalmol. 5, 1–8 (2005)
48. N. Lee, A.F. Laine, I. Barbazetto, M. Busuoic, R. Smith, Level set segmentation of geographic
atrophy in macular autofluorescence images. Invest. Ophthalmol. Vis. Sci. 47(10) (2006)
49. N. Lee, A.F.Laine, R.T. Smith, A hybrid segmentation approach for geographic atrophy in fundus auto-fluorescence images for diagnosis of age-related macular degeneration, in Proceeding
of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology
Society, 4965–4968 2007
50. N. Lee, A.F. Laine, R.T. Smith, Interactive segmentation for geographic atrophy in retinal
fundus images, in the 42nd Asilomar Conference on Signals, Systems and Computers, vol. 42,
pp. 655–658 2008
51. R.G. Sayegh, C. Simader, U. Schechy, A. Montuoro, C. Kiss, S. Sacu, D.P. Kreil, C. Prunte,
U. Schmidt-Erfurth, A systematic comparison of spectral-domain optical coherence tomography and fundus autofluorescence in patients with geographic atrophy. Ophthalmology 118(9),
1844–1851 (2011)
52. S.J. Chiu, J.A. Izatt, R.V. O’Connell, K.P. Winter, C.A. Toth, S. Farsiu, Validated automatic
segmentation of AMD pathology including drusen and geographic atrophy in SDOCT images.
Invest. Ophthalmol. Vis. Sci. 53(1), 53–61 (2012)
53. C. Schütze, C. Ahlers, S. Sacu, G. Mylonas, R. Sayegh, I. Golbaz, G. Matt, G. Stock, U.
Schmidt-Erfurth, Performance of OCT segmentation procedures to assess morphology and
extension in geographic atrophy. Acta. Ophthalmol. 89(3), 235–240 (2011)
