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13. D. Barthelmes, M.C. Gillies, F.K. Sutter, Quantitative OCT analysis of idiopathic perifoveal
telangiectasia. Invest. Ophthalmol. Vis. Sci. 49(5), 2156–2162 (2008)
14. J. Van der Schoot, K.A. Vermeer, J.F. de Boer, H.G. Lemij, The effect of glaucoma on the optical
attenuation coefficient of the retinal nerve fiber layer in spectral domain optical coherence
tomography images. Invest. Ophthalmol. Vis. Sci. 53(4), 2424–30 (2012)
15. K.A. Vermeer, J. van der Schoot, H.G. Lemij, J.F. de Boer, RPE-normalized RNFL attenuation coefficient maps derived from volumetric OCT imaging for glaucoma assessment. Invest.
Ophthalmol. Vis. Sci. 53(10), 6102–6108 (2012)
16. A. Giani, D.D. Esmaili, C. Luiselli, M. Cigada, P. Salvetti, J.W. Miller, G. Staurenghi, Displayed
reflectivity of choroidal neovascular membranes by optical coherence tomography correlates
with presence of leakage by fluorescein angiography. Retina 31(5), 942–948 (2011)
17. S. Ooto, M. Hangai, A. Tomidokoro, H. Saito, M. Araie, T. Otani, S. Kishi, K. Matsushita, N.
Maeda, M. Shirakashi, H. Abe, S. Ohkubo, K. Sugiyama, A. Iwase, N. Yoshimura, Effects of
age, sex, and axial length on the three-dimensional profile of normal macular layer structures.
Invest. Ophthalmol. Vis. Sci. 52(12), 8769–8779 (2011)
18. C.Y. Cheung, D. Chen, T.Y. Wong, Y.C. Tham, R. Wu, Y. Zheng, C.Y. Cheng, S.M. Saw,
M. Baskaran, C.K. Leung, T. Aung, Determinants of quantitative optic nerve measurements
using spectral domain optical coherence tomography in a population-based sample of nonglaucomatous subjects. Invest. Ophthalmol. Vis. Sci. 52(13), 9629–9635 (2011)
19. T. Alasil, K. Wang, P.A. Keane, H. Lee, N. Baniasadi, J.F. de Boer, T.C. Chen, Analysis of
normal retinal nerve fiber layer thickness by age, sex, and race using spectral domain optical
coherence tomography. J. Glaucoma 22(7), 532–541 (2013)
20. M.D. Abràmoff, M.K. Garvin, M. Sonka, Retinal imaging and image analysis. IEEE Trans.
Med. Imaging 3, 169–208 (2010)
21. M.K. Garvin, M.D. Abràmoff, X. Wu et al., Automated 3-D intraretinal layer segmentation of
macular spectral-domain optical coherence tomography images. IEEE Trans. Med. Imaging
28(9), 1436–1447 (2009)
22. X. Chen, M. Niemeijer, L. Zhang, K. Lee, M.D. Abramoff, M. Sonka, 3D segmentation of fluidassociated abnormalities in retinal OCT: probability constrained graph-search–graph-cut. Med.
Imaging IEEE Trans. 31(8), 1521–1531 (2012)
23. F. Shi, X. Chen, H. Zhao, W. Zhu, D. Xiang, E. Gao, M. Sonka, H. Chen, Automated 3D retinal layer segmentation of macular optical coherence tomography images with serous
pigment epithelial detachments. IEEE Trans. Med. Imaging 34(2), 441–452 (2015)
24. X. Chen, P. Hou, C. Jin, W. Zhu, X. Luo, F. Shi, M. Sonka, H. Chen, Quantitative analysis
of retinal layer optical intensities on three-dimensional optical coherence tomography. Invest.
Ophthalmol. Vis. Sci. 54(10), 6846 (2013)
25. B. Chen, E. Gao, H. Chen, J. Yang, F. Shi, C. Zheng, W. Zhu, D. Xiang, X. Chen, M. Zhang,
Profile and determinants of retinal optical intensity in normal eyes with spectral domain optical
coherence tomography. Plos One 11(2) (2016)
26. Retinopathy/Pathology D. Photocoagulation for diabetic macular edema. Early treatment diabetic retinopathy study report number 1. Early Treatment Diabetic Retinopathy Study research
group. Arch. Ophthalmol. 103(12), 1796–806 (1985)
27. H. Chen, X. Chen, Z. Qiu, D. Xiang, W. Chen, F. Shi, J. Zheng, W. Zhu, M. Sonka, Quantitative
analysis of retinal layers’ optical intensities on 3D optical coherence tomography for central
retinal artery occlusion. Sci. Rep. 5(10), 6846–6851 (2015)
28. C.K. Leung, C.Y. Cheung, R.N. Weinreb, Q. Qiu, S. Liu, H. Li, G. Xu, N. Fan, L. Huang,
C.P. Pang, D.S. Lam, Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a variability and diagnostic performance study. Ophthalmology 116(7),
1257–1263, 63 e1-2 (2009)
29. C.K. Leung, M. Yu, R.N. Weinreb, C. Ye, S. Liu, Retinal nerve fiber layer imaging with
spectral-domain optical coherence tomography: a prospective analysis of age-related loss.
Ophthalmology 119(4), 731–737 (2012)
30. S. Cugati, D.D. Varma, C.S. Chen, A.W. Lee, Treatment options for central retinal artery
occlusion. Current Treat. Options Neurol. 15(1), 63–77 (2013)
E. Gao et al.
13. D. Barthelmes, M.C. Gillies, F.K. Sutter, Quantitative OCT analysis of idiopathic perifoveal
telangiectasia. Invest. Ophthalmol. Vis. Sci. 49(5), 2156–2162 (2008)
14. J. Van der Schoot, K.A. Vermeer, J.F. de Boer, H.G. Lemij, The effect of glaucoma on the optical
attenuation coefficient of the retinal nerve fiber layer in spectral domain optical coherence
tomography images. Invest. Ophthalmol. Vis. Sci. 53(4), 2424–30 (2012)
15. K.A. Vermeer, J. van der Schoot, H.G. Lemij, J.F. de Boer, RPE-normalized RNFL attenuation coefficient maps derived from volumetric OCT imaging for glaucoma assessment. Invest.
Ophthalmol. Vis. Sci. 53(10), 6102–6108 (2012)
16. A. Giani, D.D. Esmaili, C. Luiselli, M. Cigada, P. Salvetti, J.W. Miller, G. Staurenghi, Displayed
reflectivity of choroidal neovascular membranes by optical coherence tomography correlates
with presence of leakage by fluorescein angiography. Retina 31(5), 942–948 (2011)
17. S. Ooto, M. Hangai, A. Tomidokoro, H. Saito, M. Araie, T. Otani, S. Kishi, K. Matsushita, N.
Maeda, M. Shirakashi, H. Abe, S. Ohkubo, K. Sugiyama, A. Iwase, N. Yoshimura, Effects of
age, sex, and axial length on the three-dimensional profile of normal macular layer structures.
Invest. Ophthalmol. Vis. Sci. 52(12), 8769–8779 (2011)
18. C.Y. Cheung, D. Chen, T.Y. Wong, Y.C. Tham, R. Wu, Y. Zheng, C.Y. Cheng, S.M. Saw,
M. Baskaran, C.K. Leung, T. Aung, Determinants of quantitative optic nerve measurements
using spectral domain optical coherence tomography in a population-based sample of nonglaucomatous subjects. Invest. Ophthalmol. Vis. Sci. 52(13), 9629–9635 (2011)
19. T. Alasil, K. Wang, P.A. Keane, H. Lee, N. Baniasadi, J.F. de Boer, T.C. Chen, Analysis of
normal retinal nerve fiber layer thickness by age, sex, and race using spectral domain optical
coherence tomography. J. Glaucoma 22(7), 532–541 (2013)
20. M.D. Abràmoff, M.K. Garvin, M. Sonka, Retinal imaging and image analysis. IEEE Trans.
Med. Imaging 3, 169–208 (2010)
21. M.K. Garvin, M.D. Abràmoff, X. Wu et al., Automated 3-D intraretinal layer segmentation of
macular spectral-domain optical coherence tomography images. IEEE Trans. Med. Imaging
28(9), 1436–1447 (2009)
22. X. Chen, M. Niemeijer, L. Zhang, K. Lee, M.D. Abramoff, M. Sonka, 3D segmentation of fluidassociated abnormalities in retinal OCT: probability constrained graph-search–graph-cut. Med.
Imaging IEEE Trans. 31(8), 1521–1531 (2012)
23. F. Shi, X. Chen, H. Zhao, W. Zhu, D. Xiang, E. Gao, M. Sonka, H. Chen, Automated 3D retinal layer segmentation of macular optical coherence tomography images with serous
pigment epithelial detachments. IEEE Trans. Med. Imaging 34(2), 441–452 (2015)
24. X. Chen, P. Hou, C. Jin, W. Zhu, X. Luo, F. Shi, M. Sonka, H. Chen, Quantitative analysis
of retinal layer optical intensities on three-dimensional optical coherence tomography. Invest.
Ophthalmol. Vis. Sci. 54(10), 6846 (2013)
25. B. Chen, E. Gao, H. Chen, J. Yang, F. Shi, C. Zheng, W. Zhu, D. Xiang, X. Chen, M. Zhang,
Profile and determinants of retinal optical intensity in normal eyes with spectral domain optical
coherence tomography. Plos One 11(2) (2016)
26. Retinopathy/Pathology D. Photocoagulation for diabetic macular edema. Early treatment diabetic retinopathy study report number 1. Early Treatment Diabetic Retinopathy Study research
group. Arch. Ophthalmol. 103(12), 1796–806 (1985)
27. H. Chen, X. Chen, Z. Qiu, D. Xiang, W. Chen, F. Shi, J. Zheng, W. Zhu, M. Sonka, Quantitative
analysis of retinal layers’ optical intensities on 3D optical coherence tomography for central
retinal artery occlusion. Sci. Rep. 5(10), 6846–6851 (2015)
28. C.K. Leung, C.Y. Cheung, R.N. Weinreb, Q. Qiu, S. Liu, H. Li, G. Xu, N. Fan, L. Huang,
C.P. Pang, D.S. Lam, Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a variability and diagnostic performance study. Ophthalmology 116(7),
1257–1263, 63 e1-2 (2009)
29. C.K. Leung, M. Yu, R.N. Weinreb, C. Ye, S. Liu, Retinal nerve fiber layer imaging with
spectral-domain optical coherence tomography: a prospective analysis of age-related loss.
Ophthalmology 119(4), 731–737 (2012)
30. S. Cugati, D.D. Varma, C.S. Chen, A.W. Lee, Treatment options for central retinal artery
occlusion. Current Treat. Options Neurol. 15(1), 63–77 (2013)