7 Quantitative Analysis of Retinal Layers’ Optical Intensities …
173
Table 7.1 Mean and standard deviation of optical intensities in different layers
Mean
SD
Variance r 2 (%)
Adjusted
variance
Adjusted
SD
Adjusted
coefficient of
variation
Vitreous
13,963.50 105
11,032
27.90
7955
89.2
0.0064
Retinal nerve
fiber layer
28,516.50 1491.2
2,223,605 55.90
980,035 990
0.0347
Retinal
ganglion cells
22,821.30 1301.4
1,693,558 75.50
415,076 644.3
0.0282
Inner
plexiform
layer
22,351.70 1329.1
1,766,570 81.80
322,371 567.8
0.0254
Inner nuclear
layer
19,092.10 1047.9
1,098,045 89.90
110,480 332.4
0.0174
Outer
plexiform
layer
20,095.20 1225.2
1,501,154 89.20
162,590 403.2
0.0201
Outer nuclear
layer
17,005.00 782.7
612,695 94.70
32,542
180.4
0.0106
Photoreceptor 28,615.40 1669.9
2,788,601 62.70
1,041,087 1020.3
0.0357
Retinal
pigment
epithelium
30,780.20 1489.6
2,218,907 64.30
791,861 889.9
0.0289
Choroid
19,791.60 964.5
930,165 58.40
386,699 621.9
0.0314
All areas
15,863.30 292.3
85,435
87.60
10,630
103.1
0.0065
7.3.3 Results of Quantitative Analysis of Retinal Layer
Optical Intensities of Normal Subjects
The mean, standard deviation and adjusted standard deviation of different layers’
optical intensities were listed in Table 7.1 and showed in Fig. 7.2.
As shown in Fig. 7.3, the correlation among the optical intensities of intraretinal
layers were moderate to good, with r ranged from 0.524 to 0.988, all p < 0.001. Among
them, the correlation between optical intensities of GCL, IPL, INL, OPL were very
strong, with r > 0.934, all p < 10
−18 . On the contrary, the correlation of intensities
of vitreous with all intraretinal layers were only mild to moderate, with r ranged
from 0.363 to 0.541 (all p < 0.03), except the low correlation with photoreceptor
(r 0.251, p 0.119). The choroid layer’s intensity had moderate correlation with
intraretinal layers, with r ranging from 0.418 to 0.725 (all p < 0.01).
Totally 23 male and 17 female subjects were included in the study. The mean
age were 37.9 ± 14.9 years old. No statistically difference of the optical intensities were found in any layers between male and female (all p > 0.05). The mean
173
Table 7.1 Mean and standard deviation of optical intensities in different layers
Mean
SD
Variance r 2 (%)
Adjusted
variance
Adjusted
SD
Adjusted
coefficient of
variation
Vitreous
13,963.50 105
11,032
27.90
7955
89.2
0.0064
Retinal nerve
fiber layer
28,516.50 1491.2
2,223,605 55.90
980,035 990
0.0347
Retinal
ganglion cells
22,821.30 1301.4
1,693,558 75.50
415,076 644.3
0.0282
Inner
plexiform
layer
22,351.70 1329.1
1,766,570 81.80
322,371 567.8
0.0254
Inner nuclear
layer
19,092.10 1047.9
1,098,045 89.90
110,480 332.4
0.0174
Outer
plexiform
layer
20,095.20 1225.2
1,501,154 89.20
162,590 403.2
0.0201
Outer nuclear
layer
17,005.00 782.7
612,695 94.70
32,542
180.4
0.0106
Photoreceptor 28,615.40 1669.9
2,788,601 62.70
1,041,087 1020.3
0.0357
Retinal
pigment
epithelium
30,780.20 1489.6
2,218,907 64.30
791,861 889.9
0.0289
Choroid
19,791.60 964.5
930,165 58.40
386,699 621.9
0.0314
All areas
15,863.30 292.3
85,435
87.60
10,630
103.1
0.0065
7.3.3 Results of Quantitative Analysis of Retinal Layer
Optical Intensities of Normal Subjects
The mean, standard deviation and adjusted standard deviation of different layers’
optical intensities were listed in Table 7.1 and showed in Fig. 7.2.
As shown in Fig. 7.3, the correlation among the optical intensities of intraretinal
layers were moderate to good, with r ranged from 0.524 to 0.988, all p < 0.001. Among
them, the correlation between optical intensities of GCL, IPL, INL, OPL were very
strong, with r > 0.934, all p < 10
−18 . On the contrary, the correlation of intensities
of vitreous with all intraretinal layers were only mild to moderate, with r ranged
from 0.363 to 0.541 (all p < 0.03), except the low correlation with photoreceptor
(r 0.251, p 0.119). The choroid layer’s intensity had moderate correlation with
intraretinal layers, with r ranging from 0.418 to 0.725 (all p < 0.01).
Totally 23 male and 17 female subjects were included in the study. The mean
age were 37.9 ± 14.9 years old. No statistically difference of the optical intensities were found in any layers between male and female (all p > 0.05). The mean