297
Dahmoune F, Nayak B, Moussi K et al (2015) Optimization of microwave-assisted extraction
of polyphenols from Myrtus communis L. leaves. Food Chem 166:585–595. https://doi.
org/10.1016/j.foodchem.2014.06.066
Dai F, Chen W-F, Zhou B (2008) Antioxidant synergism of green tea polyphenols with α-tocopherol
and l-ascorbic acid in SDS micelles. Biochimie 90:1499–1505. https://doi.org/10.1016/j.
biochi.2008.05.007
Dai Y, van Spronsen J, Witkamp G-J et al (2013a) Ionic Liquids and Deep Eutectic Solvents in
natural products research: mixtures of solids as extraction solvents. J Nat Prod 76:2162–2173.
https://doi.org/10.1021/np400051w
Dai Y, van Spronsen J, Witkamp G-J et al (2013b) Natural deep eutectic solvents as new potential media for green technology. Anal Chim Acta 766:61–68. https://doi.org/10.1016/j.
aca.2012.12.019
Dai Y, Witkamp G-J, Verpoorte R, Choi YH (2013c) Natural Deep Eutectic Solvents as a new
extraction media for phenolic metabolites in Carthamus tinctorius L. Anal Chem 85:6272–6278.
https://doi.org/10.1021/ac400432p
Dai Y, Witkamp G-J, Verpoorte R, Choi YH (2015) Tailoring properties of natural deep eutectic solvents with water to facilitate their applications. Food Chem 187:14–19. https://doi.
org/10.1016/j.foodchem.2015.03.123
Dai Y, Rozema E, Verpoorte R, Choi YH (2016) Application of natural deep eutectic solvents
to the extraction of anthocyanins from Catharanthus roseus with high extractability and stability replacing conventional organic solvents. J Chromatogr A 1434:50–56. https://doi.
org/10.1016/j.chroma.2016.01.037
de Heer MI, Korth H-G, Mulder P (1999) Poly methoxy phenols in solution: O−H bond dissociation enthalpies, structures, and hydrogen bonding. J Org Chem 64:6969–6975. https://doi.
org/10.1021/jo9901485
Deng J, Yang H, Capanoglu E et al (2018) Technological aspects and stability of polyphenols. In:
Polyphenols: properties, recovery, and applications. Elsevier, Oxford, pp 295–323
Du Y, Guo H, Lou H (2007) Grape seed polyphenols protect cardiac cells from apoptosis via
induction of endogenous antioxidant enzymes. J Agric Food Chem 55:1695–1701. https://doi.
org/10.1021/jf063071b
Duan L, Dou L-L, Guo L et al (2016) Comprehensive evaluation of Deep Eutectic Solvents in
extraction of bioactive natural products. ACS Sustain Chem Eng 4:2405–2411. https://doi.
org/10.1021/acssuschemeng.6b00091
Duan L, Zhang W-H, Zhang Z-H et al (2019) Evaluation of natural deep eutectic solvents for
the extraction of bioactive flavone C-glycosides from Flos Trollii. Microchem J 145:180–186.
https://doi.org/10.1016/j.microc.2018.10.031
Durand E, Lecomte J, Upasani R et al (2017) Evaluation of the ROS inhibiting activity and mitochondrial targeting of phenolic compounds in fibroblast cells Model system and enhancement of
efficiency by Natural Deep Eutectic Solvent (NADES) formulation. Pharm Res 34:1134–1146.
https://doi.org/10.1007/s11095-017-2124-4
Dwamena AK (2019) Recent advances in hydrophobic deep eutectic solvents for extraction.
Separations 6:9. https://doi.org/10.3390/separations6010009
El Kantar S, Rajha HN, Boussetta N et al (2019) Green extraction of polyphenols from grapefruit
peels using high voltage electrical discharges, deep eutectic solvents and aqueous glycerol.
Food Chem 295:165–171. https://doi.org/10.1016/j.foodchem.2019.05.111
Faggian M, Sut S, Perissutti B et al (2016) Natural Deep Eutectic Solvents (NADES) as a tool for
bioavailability improvement: pharmacokinetics of Rutin dissolved in Proline/Glycine after oral
administration in rats: possible application in nutraceuticals. Molecules 21:1531. https://doi.
org/10.3390/molecules21111531
Feduraev P, Chupakhina G, Maslennikov P et al (2019) Variation in phenolic compounds content
and antioxidant activity of different plant organs from Rumex crispus L. and Rumex obtusifolius L. at different growth stages. Antioxidants 8:237. https://doi.org/10.3390/antiox8070237
7 Extraction of Plant and Algal Polyphenols Using Eutectic Solvents
Dahmoune F, Nayak B, Moussi K et al (2015) Optimization of microwave-assisted extraction
of polyphenols from Myrtus communis L. leaves. Food Chem 166:585–595. https://doi.
org/10.1016/j.foodchem.2014.06.066
Dai F, Chen W-F, Zhou B (2008) Antioxidant synergism of green tea polyphenols with α-tocopherol
and l-ascorbic acid in SDS micelles. Biochimie 90:1499–1505. https://doi.org/10.1016/j.
biochi.2008.05.007
Dai Y, van Spronsen J, Witkamp G-J et al (2013a) Ionic Liquids and Deep Eutectic Solvents in
natural products research: mixtures of solids as extraction solvents. J Nat Prod 76:2162–2173.
https://doi.org/10.1021/np400051w
Dai Y, van Spronsen J, Witkamp G-J et al (2013b) Natural deep eutectic solvents as new potential media for green technology. Anal Chim Acta 766:61–68. https://doi.org/10.1016/j.
aca.2012.12.019
Dai Y, Witkamp G-J, Verpoorte R, Choi YH (2013c) Natural Deep Eutectic Solvents as a new
extraction media for phenolic metabolites in Carthamus tinctorius L. Anal Chem 85:6272–6278.
https://doi.org/10.1021/ac400432p
Dai Y, Witkamp G-J, Verpoorte R, Choi YH (2015) Tailoring properties of natural deep eutectic solvents with water to facilitate their applications. Food Chem 187:14–19. https://doi.
org/10.1016/j.foodchem.2015.03.123
Dai Y, Rozema E, Verpoorte R, Choi YH (2016) Application of natural deep eutectic solvents
to the extraction of anthocyanins from Catharanthus roseus with high extractability and stability replacing conventional organic solvents. J Chromatogr A 1434:50–56. https://doi.
org/10.1016/j.chroma.2016.01.037
de Heer MI, Korth H-G, Mulder P (1999) Poly methoxy phenols in solution: O−H bond dissociation enthalpies, structures, and hydrogen bonding. J Org Chem 64:6969–6975. https://doi.
org/10.1021/jo9901485
Deng J, Yang H, Capanoglu E et al (2018) Technological aspects and stability of polyphenols. In:
Polyphenols: properties, recovery, and applications. Elsevier, Oxford, pp 295–323
Du Y, Guo H, Lou H (2007) Grape seed polyphenols protect cardiac cells from apoptosis via
induction of endogenous antioxidant enzymes. J Agric Food Chem 55:1695–1701. https://doi.
org/10.1021/jf063071b
Duan L, Dou L-L, Guo L et al (2016) Comprehensive evaluation of Deep Eutectic Solvents in
extraction of bioactive natural products. ACS Sustain Chem Eng 4:2405–2411. https://doi.
org/10.1021/acssuschemeng.6b00091
Duan L, Zhang W-H, Zhang Z-H et al (2019) Evaluation of natural deep eutectic solvents for
the extraction of bioactive flavone C-glycosides from Flos Trollii. Microchem J 145:180–186.
https://doi.org/10.1016/j.microc.2018.10.031
Durand E, Lecomte J, Upasani R et al (2017) Evaluation of the ROS inhibiting activity and mitochondrial targeting of phenolic compounds in fibroblast cells Model system and enhancement of
efficiency by Natural Deep Eutectic Solvent (NADES) formulation. Pharm Res 34:1134–1146.
https://doi.org/10.1007/s11095-017-2124-4
Dwamena AK (2019) Recent advances in hydrophobic deep eutectic solvents for extraction.
Separations 6:9. https://doi.org/10.3390/separations6010009
El Kantar S, Rajha HN, Boussetta N et al (2019) Green extraction of polyphenols from grapefruit
peels using high voltage electrical discharges, deep eutectic solvents and aqueous glycerol.
Food Chem 295:165–171. https://doi.org/10.1016/j.foodchem.2019.05.111
Faggian M, Sut S, Perissutti B et al (2016) Natural Deep Eutectic Solvents (NADES) as a tool for
bioavailability improvement: pharmacokinetics of Rutin dissolved in Proline/Glycine after oral
administration in rats: possible application in nutraceuticals. Molecules 21:1531. https://doi.
org/10.3390/molecules21111531
Feduraev P, Chupakhina G, Maslennikov P et al (2019) Variation in phenolic compounds content
and antioxidant activity of different plant organs from Rumex crispus L. and Rumex obtusifolius L. at different growth stages. Antioxidants 8:237. https://doi.org/10.3390/antiox8070237
7 Extraction of Plant and Algal Polyphenols Using Eutectic Solvents