286
polyphenols is an issue. While viscosity is sometimes a complex problem to solve
in the laboratory, it may constitute a real barrier to the industrial development of
extraction applications.
7.4.4 Response Surface Methodology
As mentioned above, the extraction efficiency could be maximized through optimization of multiple variables which may interact with each other. Response surface
methodology (RSM) is now often employed to address the different extraction conditions by considering all the parameters together (Fig. 7.9). Bi and coworkers have
Fig. 7.9 Response surface methodology plot of the model for extraction of lithospermic acid in
Radix Salviae miltiorrhizae from (Chen et al. 2016) copyright MDPI 2016. Plant/solvent ratio (A),
(B), (C), power of irradiation (B), (D), temperature (A), and duration (B), (C) were examined
together. Such plot allows a screening of all parameters and takes into account their possible
interactions
L. Percevault et al.
polyphenols is an issue. While viscosity is sometimes a complex problem to solve
in the laboratory, it may constitute a real barrier to the industrial development of
extraction applications.
7.4.4 Response Surface Methodology
As mentioned above, the extraction efficiency could be maximized through optimization of multiple variables which may interact with each other. Response surface
methodology (RSM) is now often employed to address the different extraction conditions by considering all the parameters together (Fig. 7.9). Bi and coworkers have
Fig. 7.9 Response surface methodology plot of the model for extraction of lithospermic acid in
Radix Salviae miltiorrhizae from (Chen et al. 2016) copyright MDPI 2016. Plant/solvent ratio (A),
(B), (C), power of irradiation (B), (D), temperature (A), and duration (B), (C) were examined
together. Such plot allows a screening of all parameters and takes into account their possible
interactions
L. Percevault et al.