219
Table 6.10 Examples of the application of combined extraction techniques with deep eutectic
solvents as extraction solvents
Extraction
medium
Target
compounds
DES:HBA/HBD (molar
ratio)
Extraction method References
Equisetum
palustre L.
Flavonoids
Choline chloride/
glycerol, betaine
hydrochloride/glycerol,
choline chloride/1,4
butanediol, betaine
hydrochloride/1,4
butanediol, choline
chloride/1,3-butanediol,
betaine
hydrochloride/1,3butanediol, choline
chloride/ethylene glycol,
betaine hydrochloride/
ethylene glycol, and
choline chloride/betaine
hydrochloride/ethylene
glycol (n.m.). Choline
chloride/betaine
hydrochloride/ethylene
glycol (1:1:2) was the
optimal DES.
DES-based
negative-pressure
cavitation-assisted
extraction method
coupled to
macroporous resin
enrichment
Qi et al.
(2015)
Radix
Scutellariae
Flavonoids:
baicalin,
wogonoside,
baicalein, and
wogonin
Choline chloride/1,4butanediol (1:2), choline
chloride/glycerol (1:2),
choline chloride/ethylene
glycol (1:2), choline
chloride/citric acid (1:2),
choline chloride/malic
acid (1:2), choline
chloride/lactic acid (1:2,
3:1, 2:1, 1:1, 1:3, 1:4),
choline chloride/glucose
(1:2), choline chloride/
sorbitol (1:2), choline
chloride/sucrose (1:2),
choline chloride/maltose
(1:2), citric acid/sucrose
(1:2), citric acid/glucose
(1:2), and lactic acid/
sucrose (1:2)
Natural deep
eutectic solventbased microwave
extraction coupled
to direct
macroporous resin
adsorption and
desorption process
Wei et al.
(2015)
Bamboo shoot
shell
Lignin and xylan Choline chloride/organic
acid (1:2), choline
chloride/ethylene glycol
(1:2), and choline
chloride/glycerol (1:2)
Biological
treatment based on
microorganisms
coupled to DES
pretreatment
Dai et al.
(2017)
(continued)
6 Methods for Extraction of Bioactive Compounds from Plant and Animal Matter…