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Table 2.7 What cyclodextrin for what purpose? (CD, cyclodextrin; SBE, sulfobutyl-β-cyclodextrin; MeCD, methylated cyclodextrin)
Drugs/parenteral
Drugs/per os
Drugs/topical
Cosmetics
Foods
Biotechnology
Analytical chemistry
Chemical industry
αCD
+
+++
+++
+++
+
+
+
+
βCD
−
+++
+
+
++
++
+++
γCD
+
+++
+++
+++
+++
−
+++
HPβCD
++
++
+++
+++
−
++
++
++
SBE
+++
+
−
−
−
−
++
−
MeCD
+
+
+
−
−
+++
++
+++
“−”: not recommended, either on account of toxic side effects or too high prices
“+”: in limited number of cases
“++”: can be recommended, but for the same purpose, there is better or cheaper candidate
“+++”: most recommended because of existing approval, acceptable price, and technical performance
G. Crini et al.