138
such as drugs, insect repellents, and antimicrobial agents. These polymers were also
found to be efficient adsorbents for environmental purposes (Otta et al. 1988).
Ten years later, Professor Szejtli patented a method to bind cyclodextrins chemically to fibers in order to prepare medical bandages (Szejtli et al. 1991). A cellulose
fabric (2.5 g) containing chemically bound β-cyclodextrin was treated with 50 mL
solution of 1% I 2 and 0.7% KI in 75% ethanol, followed by solvent removal, to give
a medicated bandage. Binding cyclodextrin to fibers chemically opened up new
ways for the preparation of perfumed textiles and cosmeto-textiles. The applications
of cyclodextrins in the textile industry were published in 2003 (Szejtli 2003).
In 1983, at the 34th Starch Convention at Detmold, Professor Szejtli presented
his results on the physiological effects of cyclodextrins on plants (Szejtli 1983a). As
biologically active substances, cyclodextrins can be used as plant growth regulators.
Treating cereal seeds with cyclodextrin, germination, i.e., development of shoots
and roots, was retarded in the first few days as compared to the control seeds, but
after some days, this initial stress effect was followed by a more vigorous growing
of the new plant; the accelerated development resulted in higher green mass,
enhanced ramification, more ears per plant, and higher crop yield. In several cases,
a higher resistance of the cyclodextrin-treated plants to phytotoxic herbicides was
also observed. The height and dry mass of 4-week-old plants developed from
cyclodextrin- treated seeds under laboratory conditions were significantly higher
than those of the control plants.
The most significant effects published in agrochemistry and complexation of
pesticides were the increase of solubility, the stabilization of substances against
rapid decomposition by sunlight, conversion of volatile insecticides into nonvolatile, long-lasting formulations, prevention of the phytotoxic effect of certain fungicides, etc. (Szejtli 1983a, 1984a, 1985a, b).
The interaction of some nonionic tensides with native cyclodextrins (Szejtli
1987c, d; Bujtas et al. 1987; Szogyi et al. 1987) and insoluble β-cyclodextrin polymer was studied (Fenyvesi et al. 1992). The results showed a reduction of the phytotoxicity of tensides after complexation with cyclodextrins (Szejtli 1987c; Bujtas
et al. 1987). Cyclodextrin polymer can also bind alkylphenol polyoxyethylene glycol ethers (Fenyvesi et al. 1992) more effectively than polymer produced from linear dextran. Professor Szejtli suggested that polymer could efficiently be used for
the elimination of tensides from aqueous solutions.
In 1996, the same material was proved to be effective in healing the wounds
inflicted on the back of rats and in healing venous leg ulcers of human patients
(Felméray et al. 1996). According to microscopic studies, cyclodextrin polymer in
bead form implanted into the muscular tissue of rats did not cause inflammation cell
reaction for up to 6-week observation period.
In 1999, Professor Szejtli demonstrated that cyclodextrins were ideal candidates
for iodine adsorption from nuclear waste gases (Szente et al. 1999a, b). In particular,
methylated α-cyclodextrin and α-cyclodextrin polymers had high adsorption capacity. Such materials could also be used in the air filtration systems.
The same year, a work on the inclusion complexes of UV filters in solution and
in solid state was published (Fenyvesi et al. 1999b). The aqueous solubility of the
G. Crini et al.
such as drugs, insect repellents, and antimicrobial agents. These polymers were also
found to be efficient adsorbents for environmental purposes (Otta et al. 1988).
Ten years later, Professor Szejtli patented a method to bind cyclodextrins chemically to fibers in order to prepare medical bandages (Szejtli et al. 1991). A cellulose
fabric (2.5 g) containing chemically bound β-cyclodextrin was treated with 50 mL
solution of 1% I 2 and 0.7% KI in 75% ethanol, followed by solvent removal, to give
a medicated bandage. Binding cyclodextrin to fibers chemically opened up new
ways for the preparation of perfumed textiles and cosmeto-textiles. The applications
of cyclodextrins in the textile industry were published in 2003 (Szejtli 2003).
In 1983, at the 34th Starch Convention at Detmold, Professor Szejtli presented
his results on the physiological effects of cyclodextrins on plants (Szejtli 1983a). As
biologically active substances, cyclodextrins can be used as plant growth regulators.
Treating cereal seeds with cyclodextrin, germination, i.e., development of shoots
and roots, was retarded in the first few days as compared to the control seeds, but
after some days, this initial stress effect was followed by a more vigorous growing
of the new plant; the accelerated development resulted in higher green mass,
enhanced ramification, more ears per plant, and higher crop yield. In several cases,
a higher resistance of the cyclodextrin-treated plants to phytotoxic herbicides was
also observed. The height and dry mass of 4-week-old plants developed from
cyclodextrin- treated seeds under laboratory conditions were significantly higher
than those of the control plants.
The most significant effects published in agrochemistry and complexation of
pesticides were the increase of solubility, the stabilization of substances against
rapid decomposition by sunlight, conversion of volatile insecticides into nonvolatile, long-lasting formulations, prevention of the phytotoxic effect of certain fungicides, etc. (Szejtli 1983a, 1984a, 1985a, b).
The interaction of some nonionic tensides with native cyclodextrins (Szejtli
1987c, d; Bujtas et al. 1987; Szogyi et al. 1987) and insoluble β-cyclodextrin polymer was studied (Fenyvesi et al. 1992). The results showed a reduction of the phytotoxicity of tensides after complexation with cyclodextrins (Szejtli 1987c; Bujtas
et al. 1987). Cyclodextrin polymer can also bind alkylphenol polyoxyethylene glycol ethers (Fenyvesi et al. 1992) more effectively than polymer produced from linear dextran. Professor Szejtli suggested that polymer could efficiently be used for
the elimination of tensides from aqueous solutions.
In 1996, the same material was proved to be effective in healing the wounds
inflicted on the back of rats and in healing venous leg ulcers of human patients
(Felméray et al. 1996). According to microscopic studies, cyclodextrin polymer in
bead form implanted into the muscular tissue of rats did not cause inflammation cell
reaction for up to 6-week observation period.
In 1999, Professor Szejtli demonstrated that cyclodextrins were ideal candidates
for iodine adsorption from nuclear waste gases (Szente et al. 1999a, b). In particular,
methylated α-cyclodextrin and α-cyclodextrin polymers had high adsorption capacity. Such materials could also be used in the air filtration systems.
The same year, a work on the inclusion complexes of UV filters in solution and
in solid state was published (Fenyvesi et al. 1999b). The aqueous solubility of the
G. Crini et al.