80
5 Gone with the Flow: Miniaturization and Safer Chemistry
Fig. 5.8 A telescoped eight-step system with adoption of machine assistance leading to a polycyclic
intermediate of biological interest. Copyright 2016 the American Chemical Society. Reproduced
with permission
from those of larger scales (Bruus 2012). In particular, laminar flow characterized by
low numbers of Reynolds takes place in microchannels. Acoustic cavitation does not
occur easily in microfluidics because of the high static pressure inside the microchannel, which promotes the fast dissolution of microbubbles. In practice, small particles
5 Gone with the Flow: Miniaturization and Safer Chemistry
Fig. 5.8 A telescoped eight-step system with adoption of machine assistance leading to a polycyclic
intermediate of biological interest. Copyright 2016 the American Chemical Society. Reproduced
with permission
from those of larger scales (Bruus 2012). In particular, laminar flow characterized by
low numbers of Reynolds takes place in microchannels. Acoustic cavitation does not
occur easily in microfluidics because of the high static pressure inside the microchannel, which promotes the fast dissolution of microbubbles. In practice, small particles