alkaliphiles are trickling in. With such moves, one expects the rise in the interest
among industrialists to realize the enormous potential of alkaliphiles.
References
1. Transparency (2016) Global Biotechnology market recovering from post-recession crunch,
expected to reach US$414.5 bn by 2017. https://www.transparencymarketresearch.com/
pressrelease/global-biotechnology-market.htm. Accessed 18 Feb 2020
2. Global Market Insights (2019) Biotechnology market size to exceed $729bn by 2025. https://
www.gminsights.com/pressrelease/biotechnology-market. Accessed 18 Feb 2020
3. Fiala G, Stetter KO (1986) Pyrococcus furiosus sp. nov., represents a novel genus of marine
heterotrophic archaebacteria growing optimally at 100
C. Arch Microbiol 145:56–61
4. Kisková J, Stramová Z, Javorský P, Sedláková-Kaduková J, Pristaš P (2019) Analysis of the
bacterial community from high alkaline (pH > 13) drainage water at a brown mud disposal site
near Žiar nad Hronom (Banská Bystrica region, Slovakia) using 454 pyrosequencing. Folia
Microbiol 64:83–90
5. Mei N, Postec A, Erauso G, Joseph M, Pelletier B, Payri C et al (2016) Serpentinicella
alkaliphila gen. nov., sp. nov., a novel alkaliphilic anaerobic bacterium isolated from the
serpentinite-hosted Prony hydrothermal field, New Caledonia. Int J Syst Evol Microbiol
66:4464–4470
6. Schleper C, Pühler G, Kühlmorgen B, Zillig W (1995) Life at extremely low pH. Nature
375:741–742
7. Xu Y, Nogi Y, Kato C, Liang Z, Rüger HJ, De Kegel D, Glansdorff N (2003) Moritella
profunda sp. nov. and Moritella abyssi sp. nov., two psychropiezophilic organisms isolated
from deep Atlantic sediments. Int J Syst Evol Microbiol 53:533–538
8. Margesin R, Collins T (2019) Microbial ecology of the cryosphere (glacial and permafrost
habitats): current knowledge. Appl Microbiol Biotechnol 103:2537–2549
9. Kashefi K, Lovley DR (2003) Extending the upper temperature limit for life. Science 301:934
10. Rothschild L, Mancinelli R (2001) Life in extreme environments. Nature 409:1092–1101
11. Grant S, Grant WD, Jones BE, Kato C, Lina L (1999) Novel archaeal phylotypes from an East
Aftrican alkaline saltern. Extremophiles 3:139–145
12. Rampelotto PH (2013) Extremophiles and extreme environments. Life (Basel) 3:482–485
13. Satyanarayana T, Raghukumar C, Sisinthy S (2005) Extremophilic microbes: diversity and
perspectives. Curr Sci 89:78–90
14. Ventosa A, de la Haba RR, Sánchez-Porro C, Papke RT (2015) Microbial diversity of
hypersaline environments: a metagenomic approach. Curr Opin Microbiol 25:80–87
15. Aguilera A (2013) Eukaryotic organisms in extreme acidic environments, the Río Tinto case.
Life (Basel) 3:363–374
16. Kavembe GD, Meyer A, Wood CM (2016) Fish populations in East African saline lakes in
Soda Lakes of East Africa. Springer, Cham, pp 227–257
17. Lanzén A, Simachew A, Gessesse A, Chmolowska D, Jonassen I, Øvreås L (2013) Surprising
prokaryotic and eukaryotic diversity, community structure and biogeography of Ethiopian
soda lakes. PLoS One 8(8):e72577
18. Singh R, Kumar M, Mittal A, Mehta PK (2016) Microbial enzymes: industrial progress in 21st
century. 3 Biotech 6:174. https://doi.org/10.1007/s13205-016-0485-8
19. Lentzen G, Schwarz T (2006) Extremolytes: natural compounds from extremophiles for
versatile applications. Appl Microbiol Biotechnol 72:623–634
20. Van-Doan T, Hashim S, Hatti-Kaul R, Mamo G (2012) Ectoine mediated protection of enzyme
from the effect of pH and temperature stress: a study using Bacillus halodurans xylanase as a
model. Appl Microbiol Biotechnol 97:6271–6278
Alkaliphiles: The Versatile Tools in Biotechnology
37
among industrialists to realize the enormous potential of alkaliphiles.
References
1. Transparency (2016) Global Biotechnology market recovering from post-recession crunch,
expected to reach US$414.5 bn by 2017. https://www.transparencymarketresearch.com/
pressrelease/global-biotechnology-market.htm. Accessed 18 Feb 2020
2. Global Market Insights (2019) Biotechnology market size to exceed $729bn by 2025. https://
www.gminsights.com/pressrelease/biotechnology-market. Accessed 18 Feb 2020
3. Fiala G, Stetter KO (1986) Pyrococcus furiosus sp. nov., represents a novel genus of marine
heterotrophic archaebacteria growing optimally at 100
C. Arch Microbiol 145:56–61
4. Kisková J, Stramová Z, Javorský P, Sedláková-Kaduková J, Pristaš P (2019) Analysis of the
bacterial community from high alkaline (pH > 13) drainage water at a brown mud disposal site
near Žiar nad Hronom (Banská Bystrica region, Slovakia) using 454 pyrosequencing. Folia
Microbiol 64:83–90
5. Mei N, Postec A, Erauso G, Joseph M, Pelletier B, Payri C et al (2016) Serpentinicella
alkaliphila gen. nov., sp. nov., a novel alkaliphilic anaerobic bacterium isolated from the
serpentinite-hosted Prony hydrothermal field, New Caledonia. Int J Syst Evol Microbiol
66:4464–4470
6. Schleper C, Pühler G, Kühlmorgen B, Zillig W (1995) Life at extremely low pH. Nature
375:741–742
7. Xu Y, Nogi Y, Kato C, Liang Z, Rüger HJ, De Kegel D, Glansdorff N (2003) Moritella
profunda sp. nov. and Moritella abyssi sp. nov., two psychropiezophilic organisms isolated
from deep Atlantic sediments. Int J Syst Evol Microbiol 53:533–538
8. Margesin R, Collins T (2019) Microbial ecology of the cryosphere (glacial and permafrost
habitats): current knowledge. Appl Microbiol Biotechnol 103:2537–2549
9. Kashefi K, Lovley DR (2003) Extending the upper temperature limit for life. Science 301:934
10. Rothschild L, Mancinelli R (2001) Life in extreme environments. Nature 409:1092–1101
11. Grant S, Grant WD, Jones BE, Kato C, Lina L (1999) Novel archaeal phylotypes from an East
Aftrican alkaline saltern. Extremophiles 3:139–145
12. Rampelotto PH (2013) Extremophiles and extreme environments. Life (Basel) 3:482–485
13. Satyanarayana T, Raghukumar C, Sisinthy S (2005) Extremophilic microbes: diversity and
perspectives. Curr Sci 89:78–90
14. Ventosa A, de la Haba RR, Sánchez-Porro C, Papke RT (2015) Microbial diversity of
hypersaline environments: a metagenomic approach. Curr Opin Microbiol 25:80–87
15. Aguilera A (2013) Eukaryotic organisms in extreme acidic environments, the Río Tinto case.
Life (Basel) 3:363–374
16. Kavembe GD, Meyer A, Wood CM (2016) Fish populations in East African saline lakes in
Soda Lakes of East Africa. Springer, Cham, pp 227–257
17. Lanzén A, Simachew A, Gessesse A, Chmolowska D, Jonassen I, Øvreås L (2013) Surprising
prokaryotic and eukaryotic diversity, community structure and biogeography of Ethiopian
soda lakes. PLoS One 8(8):e72577
18. Singh R, Kumar M, Mittal A, Mehta PK (2016) Microbial enzymes: industrial progress in 21st
century. 3 Biotech 6:174. https://doi.org/10.1007/s13205-016-0485-8
19. Lentzen G, Schwarz T (2006) Extremolytes: natural compounds from extremophiles for
versatile applications. Appl Microbiol Biotechnol 72:623–634
20. Van-Doan T, Hashim S, Hatti-Kaul R, Mamo G (2012) Ectoine mediated protection of enzyme
from the effect of pH and temperature stress: a study using Bacillus halodurans xylanase as a
model. Appl Microbiol Biotechnol 97:6271–6278
Alkaliphiles: The Versatile Tools in Biotechnology
37