Susceptibilité individuelle et toxicité de la radiothérapie 125
Références
1. Becquerel H, Curie P (1901) Action physiologique des rayons du radium. CR Acad Sci
Paris 132: 1289
2. Burnet NG, Nyman J, Turesson I, et al. (1992) Prediction of normal-tissue tolerance to
radiotherapy from in vitro cellular radiation sensitivity. Lancet 339(8809): 1570-1
3. Johansen J, Bentzen SM, Overgaard J, Overgaard M (1994) Evidence for a positive
correlation between in vitro radiosensitivity of normal human skin fibroblasts and the
occurrence of subcutaneous fibrosis after radiotherapy. Int J Radiat Biol 66(4): 407-12
4. Geara FB, Peters LJ, Ang KK, et al. (1993) Prospective comparison of in vitro normal cell
radiosensitivity and normal tissue reactions in radiotherapy patients. Int J Radiat Oncol
Biol Phys 27(5): 1173-9
5. Johansen J, Bentzen SM, Overgaard J, Overgaard M (1996) Relationship between the
in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis,
telangiectasia, and skin erythema after radiotherapy. Radiother Oncol 40(2): 101-9
6. Russell NS, Grummels A, Hart AA, et al. (1998) Low predictive value of intrinsic fibroblast
l l
radiosensitivity for fibrosis development following radiotherapy for breast cancer. Int J
Radiat Biol 73(6): 661-70
7. Peacock J, Ashton A, Bliss J, et al. (2000) Cellular radiosensitivity and complication risk
l l
after curative radiotherapy. Radiother Oncol 55(2): 173-8
8. Bentzen SM (2008) From cellular to high-throughput predictive assays in radiation
oncology: challenges and opportunities. Semin Radiat Oncol 18(2): 75-88
9. Oppitz U, Denzinger S, Nachtrab U, et al. (1999) Radiation-induced comet-formation in
human skin fibroblasts from radiotherapy patients with different normal tissue reactions.
Strahlenther Onkol 175(7): 341-6
10. Nachtrab U, Oppitz U, Flentje M, Stopper H (1998) Radiation-induced micronucleus
formation in human skin fibroblasts of patients showing severe and normal tissue damage
after radiotherapy. Int J Radiat Biol 73(3): 279-87
11. West CM, Elyan SA, Berry P, et al. (1995) A comparison of the radiosensitivity of
l l
lymphocytes from normal donors, cancer patients, individuals with ataxia-telangiectasia
(A-T) and A-T heterozygotes. Int J Radiat Biol 68(2): 197-203
12. Jones LA, Scott D, Cowan R, Roberts SA (1995) Abnormal radiosensitivity of lymphocytes
from breast cancer patients with excessive normal tissue damage after radiotherapy:
chromosome aberrations after low dose-rate irradiation. Int J Radiat Biol 67(5): 519-28
13. Floyd DN, Cassoni AM (1994) Intrinsic radiosensitivity of adult and cord blood
lymphocytes as determined by the micronucleus assay. Eur J Cancer 30A(5): 615-20
14. Huber R, Braselmann H, Bauchinger M (1992) Intra- and inter-individual variation of
background and radiation-induced micronucleus frequencies in human lymphocytes. Int J
Radiat Biol 61(5): 655-61
15. Ozsahin M, Ozsahin H, Shi Y, et al. (1997) Rapid assay of intrinsic radiosensitivity based
on apoptosis in human CD4 and CD8 T-lymphocytes. Int J Radiat Oncol Biol Phys 38(2):
429-40
16. Ozsahin M, Crompton NE, Gourgou S, et al. (2005) CD4 and CD8 T-lymphocyte
l l
apoptosis can predict radiation-induced late toxicity: a prospective study in 399 patients.
Clin Cancer Res 11(20): 7426-33
17. Azria D, Belkacemi Y, Romieu G, et al. (2010) Concurrent or sequential adjuvant letrozole
l l
and radiotherapy after conservative surgery for early-stage breast cancer (CO-HO-RT): a
phase 2 randomised trial. Lancet Oncol 11(3): 258-65
18. Pollard JM, Gatti RA (2009) Clinical radiation sensitivity with DNA repair disorders: an
overview. Int J Radiat Oncol Biol Phys 74(5): 1323-31
19. Andreassen CN, Alsner J (2009) Genetic variants and normal tissue toxicity after
radiotherapy: a systematic review. Radiother Oncol 92(3): 299-309
Références
1. Becquerel H, Curie P (1901) Action physiologique des rayons du radium. CR Acad Sci
Paris 132: 1289
2. Burnet NG, Nyman J, Turesson I, et al. (1992) Prediction of normal-tissue tolerance to
radiotherapy from in vitro cellular radiation sensitivity. Lancet 339(8809): 1570-1
3. Johansen J, Bentzen SM, Overgaard J, Overgaard M (1994) Evidence for a positive
correlation between in vitro radiosensitivity of normal human skin fibroblasts and the
occurrence of subcutaneous fibrosis after radiotherapy. Int J Radiat Biol 66(4): 407-12
4. Geara FB, Peters LJ, Ang KK, et al. (1993) Prospective comparison of in vitro normal cell
radiosensitivity and normal tissue reactions in radiotherapy patients. Int J Radiat Oncol
Biol Phys 27(5): 1173-9
5. Johansen J, Bentzen SM, Overgaard J, Overgaard M (1996) Relationship between the
in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis,
telangiectasia, and skin erythema after radiotherapy. Radiother Oncol 40(2): 101-9
6. Russell NS, Grummels A, Hart AA, et al. (1998) Low predictive value of intrinsic fibroblast
l l
radiosensitivity for fibrosis development following radiotherapy for breast cancer. Int J
Radiat Biol 73(6): 661-70
7. Peacock J, Ashton A, Bliss J, et al. (2000) Cellular radiosensitivity and complication risk
l l
after curative radiotherapy. Radiother Oncol 55(2): 173-8
8. Bentzen SM (2008) From cellular to high-throughput predictive assays in radiation
oncology: challenges and opportunities. Semin Radiat Oncol 18(2): 75-88
9. Oppitz U, Denzinger S, Nachtrab U, et al. (1999) Radiation-induced comet-formation in
human skin fibroblasts from radiotherapy patients with different normal tissue reactions.
Strahlenther Onkol 175(7): 341-6
10. Nachtrab U, Oppitz U, Flentje M, Stopper H (1998) Radiation-induced micronucleus
formation in human skin fibroblasts of patients showing severe and normal tissue damage
after radiotherapy. Int J Radiat Biol 73(3): 279-87
11. West CM, Elyan SA, Berry P, et al. (1995) A comparison of the radiosensitivity of
l l
lymphocytes from normal donors, cancer patients, individuals with ataxia-telangiectasia
(A-T) and A-T heterozygotes. Int J Radiat Biol 68(2): 197-203
12. Jones LA, Scott D, Cowan R, Roberts SA (1995) Abnormal radiosensitivity of lymphocytes
from breast cancer patients with excessive normal tissue damage after radiotherapy:
chromosome aberrations after low dose-rate irradiation. Int J Radiat Biol 67(5): 519-28
13. Floyd DN, Cassoni AM (1994) Intrinsic radiosensitivity of adult and cord blood
lymphocytes as determined by the micronucleus assay. Eur J Cancer 30A(5): 615-20
14. Huber R, Braselmann H, Bauchinger M (1992) Intra- and inter-individual variation of
background and radiation-induced micronucleus frequencies in human lymphocytes. Int J
Radiat Biol 61(5): 655-61
15. Ozsahin M, Ozsahin H, Shi Y, et al. (1997) Rapid assay of intrinsic radiosensitivity based
on apoptosis in human CD4 and CD8 T-lymphocytes. Int J Radiat Oncol Biol Phys 38(2):
429-40
16. Ozsahin M, Crompton NE, Gourgou S, et al. (2005) CD4 and CD8 T-lymphocyte
l l
apoptosis can predict radiation-induced late toxicity: a prospective study in 399 patients.
Clin Cancer Res 11(20): 7426-33
17. Azria D, Belkacemi Y, Romieu G, et al. (2010) Concurrent or sequential adjuvant letrozole
l l
and radiotherapy after conservative surgery for early-stage breast cancer (CO-HO-RT): a
phase 2 randomised trial. Lancet Oncol 11(3): 258-65
18. Pollard JM, Gatti RA (2009) Clinical radiation sensitivity with DNA repair disorders: an
overview. Int J Radiat Oncol Biol Phys 74(5): 1323-31
19. Andreassen CN, Alsner J (2009) Genetic variants and normal tissue toxicity after
radiotherapy: a systematic review. Radiother Oncol 92(3): 299-309