How will membrane protein/amphipol complexes behave in vacuum?
(# 2018 by Francis Haraux).
Fig. 14.4 Stripping a membrane protein (MacB, an ATP-binding cassette transporter) from detergent
(dodecylmaltoside) by increasing the activation energy. As the activation energy is increased from a
coefficient of 42 (cf. Fig. 14.3) in the lower spectrum (A) to 48 (B) and 52 (C) in the upper spectra,
resolved charge states are observed for the dimer of MacB. Under the highest activation conditions, a
proportion of monomeric protein becomes apparent. Inset: Expansion across three charge states reveals
binding to the dimer of phosphatidylethanolamine (PE) (From Barrera et al. 2009, # 2009 Macmillan
Publishers Limited, Nature Methods. All rights reserved).
14.1 Introduction
629
(# 2018 by Francis Haraux).
Fig. 14.4 Stripping a membrane protein (MacB, an ATP-binding cassette transporter) from detergent
(dodecylmaltoside) by increasing the activation energy. As the activation energy is increased from a
coefficient of 42 (cf. Fig. 14.3) in the lower spectrum (A) to 48 (B) and 52 (C) in the upper spectra,
resolved charge states are observed for the dimer of MacB. Under the highest activation conditions, a
proportion of monomeric protein becomes apparent. Inset: Expansion across three charge states reveals
binding to the dimer of phosphatidylethanolamine (PE) (From Barrera et al. 2009, # 2009 Macmillan
Publishers Limited, Nature Methods. All rights reserved).
14.1 Introduction
629