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bone substitute materials. Acta Biomater 2:557–565
142. Kong L, Gao Y, Lu G (2006) A study on the bioactivity of chitosan/nano-hydroxyapatite
composite scaffolds for bone tissue engineering. Eur Polym J 42:3171–3179
143. Chesnutt BM, Viano AM, Yuan Y (2009) Design and characterization of a novel chitosan/
nanocrystalline calcium phosphate composite scaffold for bone regeneration. J Biomed Mater
Res 88A:491–502
144. Kim S-H, Lim B-K, Sun F (2009) Preparation of high flexible composite film of hydroxyapatite and chitosan. Polym Bull 62:111–118
145. Araujo AB, Lemos AF, Ferreira JM (2009) Rheological, microstructural, and in vitro characterization of hybrid chitosan-polylactic acid/hydroxyapatite composites. J Biomed Mater
Res 88A:916–922
Hydroxyapatite-Packed Chitosan-PMMA Nanocomposite: A Promising Material for. . .
167