The same library approach was used in our laboratory to understand the principles required for the design of molecular electronics [138–143] and other functions,
including complex catalytic systems. The few examples illustrated here demonstrate that Staudinger’s dream of bridging macromolecular, organic, supramolecular chemistry, biology, and medicine is currently one of the most active topics of
research in the field of macromolecular chemistry, of whose existence he convinced
the organic chemistry community.
Acknowledgments Financial support by the National Science Foundation (grants
DMR-1066116, DMR-1120901, DMS-0935165, and OISE-1243313), the Humboldt Foundation,
and the P. Roy Vagelos Chair at Penn is gratefully acknowledged. The excellent contributions of
the students, postdocs, and other collaborators whose names are mentioned in the list of references
are greatly acknowledged.
References
1. Staudinger H (1905) Ber Deutsch Chem Gesell 38:1735–1739
2. Staudinger H, Meyer J (1919) Helv Chim Acta 2:635–646
3. Staudinger H (1920) Ber Deut Chem Ges 53:1073
4. Nobelprize.org (1964) Hermann Staudinger – Nobel lecture, December 11, 1953: Macromolecular chemistry. In: Nobel lectures, chemistry 1942–1962. Elsevier, Amsterdam. http://
www.nobelprize.org/nobel_prizes/chemistry/laureates/1953/staudinger-lecture.pdf
5. Mu ¨lhaupt R (2004) Angew Chem Int Ed 43:1054–1063
6. Saxon E, Bertozzi CR (2000) Science 287:2007
7. Lehn J-M (1988) Angew Chem Int Ed Engl 27:89–112
8. Abe A (2014) Staudinger’s footprints in Japan during his 30-day visit in 1957. Adv Polym
Sci. doi:10.1007/12_2013_232
9. Ringsdorf H (2014) Adv Polym Sci. doi:10.1007/12_2013_263
10. Watson JD, Crick FHC (1953) Nature 171:737–738
11. Klug A (1983) Angew Chem Int Ed Engl 22:565–582
12. Klug A (1999) Philos Trans R Soc Lond B Biol Sci 354:531–535
13. Ringsdorf H, Schlarb B, Venzmer J (1980) Angew Chem Int Ed Engl 1988(27):113–158
14. Lehn J-M (1990) Angew Chem Int Ed Engl 29:1304–1319
15. Lehn J-M (2002) Science 295:2400–2403
16. Lehn J-M (2011) CR Chim 14:348–361
17. Lehn J-M (2013) Angew Chem Int Ed 52:2836–2850
18. Yu LJ, Saupe A (1980) Phys Rev Lett 45:1000–1003
19. Malthe ˆte J, Liebert L, Levelut A-M, Galerne Y (1986) CR Acad Sci II 303:1073–1076
20. Finkelmann H, Ringsdorf H, Wendorff H (1978) Makromol Chem 179:273–276
21. Percec V (1997) Macromol Symp 117:267–273
22. Percec V, Keller A (1990) Macromolecules 23:4347–4350
23. Percec V, Heck J (1989) ACS Div Polym Chem Polym Prepr 30(2):450–451
24. Percec V (2006) Philos Trans A Math Phys Eng Sci 364:2709–2719
25. Rosen BM, Wilson CJ, Wilson DA, Peterca M, Imam MR, Percec V (2009) Chem Rev
109:6275–6540
26. Percec V, Heck J, Ungar G (1991) Macromolecules 24:4957–4962
27. Percec V, Heck J, Lee M, Ungar G, Alvarez-Castillo AJ (1992) J Mater Chem 2:1033–1039
28. Percec V, Lee M, Heck J, Blackwell HE, Ungar G, Alvarez-Castollio AJ (1992) J Mater
Chem 2:931–938
From Synthetic Macromolecules to Biological-Like Complex Systems
193
including complex catalytic systems. The few examples illustrated here demonstrate that Staudinger’s dream of bridging macromolecular, organic, supramolecular chemistry, biology, and medicine is currently one of the most active topics of
research in the field of macromolecular chemistry, of whose existence he convinced
the organic chemistry community.
Acknowledgments Financial support by the National Science Foundation (grants
DMR-1066116, DMR-1120901, DMS-0935165, and OISE-1243313), the Humboldt Foundation,
and the P. Roy Vagelos Chair at Penn is gratefully acknowledged. The excellent contributions of
the students, postdocs, and other collaborators whose names are mentioned in the list of references
are greatly acknowledged.
References
1. Staudinger H (1905) Ber Deutsch Chem Gesell 38:1735–1739
2. Staudinger H, Meyer J (1919) Helv Chim Acta 2:635–646
3. Staudinger H (1920) Ber Deut Chem Ges 53:1073
4. Nobelprize.org (1964) Hermann Staudinger – Nobel lecture, December 11, 1953: Macromolecular chemistry. In: Nobel lectures, chemistry 1942–1962. Elsevier, Amsterdam. http://
www.nobelprize.org/nobel_prizes/chemistry/laureates/1953/staudinger-lecture.pdf
5. Mu ¨lhaupt R (2004) Angew Chem Int Ed 43:1054–1063
6. Saxon E, Bertozzi CR (2000) Science 287:2007
7. Lehn J-M (1988) Angew Chem Int Ed Engl 27:89–112
8. Abe A (2014) Staudinger’s footprints in Japan during his 30-day visit in 1957. Adv Polym
Sci. doi:10.1007/12_2013_232
9. Ringsdorf H (2014) Adv Polym Sci. doi:10.1007/12_2013_263
10. Watson JD, Crick FHC (1953) Nature 171:737–738
11. Klug A (1983) Angew Chem Int Ed Engl 22:565–582
12. Klug A (1999) Philos Trans R Soc Lond B Biol Sci 354:531–535
13. Ringsdorf H, Schlarb B, Venzmer J (1980) Angew Chem Int Ed Engl 1988(27):113–158
14. Lehn J-M (1990) Angew Chem Int Ed Engl 29:1304–1319
15. Lehn J-M (2002) Science 295:2400–2403
16. Lehn J-M (2011) CR Chim 14:348–361
17. Lehn J-M (2013) Angew Chem Int Ed 52:2836–2850
18. Yu LJ, Saupe A (1980) Phys Rev Lett 45:1000–1003
19. Malthe ˆte J, Liebert L, Levelut A-M, Galerne Y (1986) CR Acad Sci II 303:1073–1076
20. Finkelmann H, Ringsdorf H, Wendorff H (1978) Makromol Chem 179:273–276
21. Percec V (1997) Macromol Symp 117:267–273
22. Percec V, Keller A (1990) Macromolecules 23:4347–4350
23. Percec V, Heck J (1989) ACS Div Polym Chem Polym Prepr 30(2):450–451
24. Percec V (2006) Philos Trans A Math Phys Eng Sci 364:2709–2719
25. Rosen BM, Wilson CJ, Wilson DA, Peterca M, Imam MR, Percec V (2009) Chem Rev
109:6275–6540
26. Percec V, Heck J, Ungar G (1991) Macromolecules 24:4957–4962
27. Percec V, Heck J, Lee M, Ungar G, Alvarez-Castillo AJ (1992) J Mater Chem 2:1033–1039
28. Percec V, Lee M, Heck J, Blackwell HE, Ungar G, Alvarez-Castollio AJ (1992) J Mater
Chem 2:931–938
From Synthetic Macromolecules to Biological-Like Complex Systems
193