acid-block-acrylamide) and lysozyme, in which the light scattering intensity is
measured as a function of the composition [32] (see Sect. 3.2.1). Principles of
this novel DLS approach addressing kinetic structural equilibration processes on
PEC systems were reported earlier by van der Burgh [33] and will be also reviewed
in a dedicated article by Lindhoud and Cohen Stuart [34].
7
6
5
4
3
2
1
0
0
0.5
sin
2 θ
2
K0/A0
K12/A10
K4/A4
K12/A0
K0/A10
I
Kc
.10 7
Fig. 2 First SLS data (Zimm
plot) on PEC particle
dispersions consisting of
cationic and anionic
copolymers of acrylamide.
(From [28] with kind
permission of Wiley-VCH)
2
3
4
6
10
D s , n m
16
25
40
63
100
158
4 . 3 5
4 . 5 5
4 . 8 5
4 . 9 3
5 . 0 1
p H
5 . 2 0
5 . 4 0
5 . 7 0
6 . 2 0
Fig. 3 First DLS data on PEC particle dispersions prepared by mixing PDADMAC (1 mg/mL)
and BSA (6.7 mg/mL) solutions. The distributions of hydrodynamic diameters at various pH
values are shown. (From [31] with kind permission of ACS)
Sizing, Shaping and Pharmaceutical Applications of Polyelectrolyte Complex. . .
201