59. Wilms D, Klos J, Frey H (2008) Microstructured reactors for polymer synthesis: a renaissance of continuous flow processes for tailor-made macromolecules? Macromol Chem Phys
209:343–356
60. Bally F, Serra CA, Hessel V et al (2010) Homogeneous polymerization: benefits brought by
microprocess technologies to the synthesis and production of polymers. Macromol React Eng
4:543–561
61. Bally F, Serra CA, Hessel V et al (2011) Micromixer-assisted polymerization processes.
Chem Eng Sci 66:1449–1462
62. Serra CA, Chang Z (2008) Microfluidic-assisted synthesis of polymer particles. Chem Eng
Technol 31:1099–1115
63. Kakuta M, Bessoth FG, Manz A (2001) Microfabricated devices for fluid mixing and their
application for chemical synthesis. Chem Rec 1:395–405
64. Hessel V, L€ owe H, Sch€ onfeld F (2005) Micromixers – a review on passive and active mixing
principles. Chem Eng Sci 60:2479–2501
65. Ehrfeld W, Golbig K, Hessel V et al (1999) Characterization of mixing in micromixers by a
test reaction: single mixing unites and mixer arrays. Ind Eng Chem Res 38:1075–1082
66. Lu H, Schmidt MA, Jensen KF (2001) Photochemical reactions and on-line UV detection in
microfabricated reactors. Lab Chip 1:22–28
67. Ueno K, Kitagawa F, Kitamura N (2002) Photocyanation of pyrene across an oil/water
interface in a polymer microchannel. Lab Chip 2:231–234
68. Fukuyama T, Hino Y, Kamata N et al (2004) Quick execution of [2+2] type photochemical
cycloaddition reaction by continuous flow system using a glass-made microreactor. Chem
Lett 33:1430–1431
69. Maeda H, Mukae H, Mizuno K (2005) Enhanced efficiency and regioselectivity of intramolecular (2p+2p) photocycloaddition of 1-cyanonaphthalene derivative using microreactors.
Chem Lett 34:66–67
70. J€ ahnisch K, Dingerdissen U (2005) For an example of endoperoxide quenching in a continuous flow system. Chem Eng Technol 28:426–427
71. Hook BD, Dohle W, Hirst PR et al (2005) A practical flow reactor for continuous organic
photochemistry. J Org Chem 70:7558–7564
72. Matsushita Y, Kumada S, Wakabayashi K et al (2006) Photocatalytic reduction in
microreactors. Chem Lett 35:410–411
73. Sugimoto A, Sumino Y, Takagi M et al (2006) High throughput evaluation of the production
of substituted acetylenes by the Sonogashira reaction followed by the Mizoroki–Heck
reaction in ionic liquids, in situ, using a novel array reactor. Tetrahedron Lett 47:6197–6200
74. Matsushita Y, Ohba N, Suzuki T et al (2008) Photocatalytic reduction of CO 2 in a
photocatalytic microreactor under gas-liquid-solid multiphase-flow condition excited by
365-nm UV-LEDs. Catal Today 132:153–158
75. Horie T, Sumino M, Tanaka T et al (2010) Photodimerization of maleic anhydride in a
microreactor without clogging. Org Process Res Dev 14:405–410
76. Yoshida J, Kataoka K, Horcajada R et al (2008) Modern strategies in electroorganic synthesis. Chem Rev 108:2265–2299
77. Yoshida J (2009) Organic electrochemistry, microreactors, and their synergy. ECS Interface,
Summer 40–45
78. L€ owe H, Ehrfeld W (1999) State-of-the-art in microreaction technology: concepts,
manufacturing and applications. Electrochim Acta 44:3679–3689
79. Suga S, Okajima M, Fujiwara K et al (2001) “Cation flow” method. A new approach to
conventional and combinatorial organic syntheses using electrochemical microflow systems.
J Am Chem Soc 123:7941–7942
80. Kupper M, Hessel V, L€ owe H et al (2003) Micro reactor for electroorganic synthesis in the
simulated moving bed-reaction and separation environment. Electrochim Acta 48:2889–2896
81. Paddon CA, Pritchard GJ, Thiemann T et al (2002) Paired electrosynthesis: micro-flow cell
processes with and without added electrolyte. Electrochem Commun 4:825–831
42
A. Nagaki and J.-i. Yoshida
209:343–356
60. Bally F, Serra CA, Hessel V et al (2010) Homogeneous polymerization: benefits brought by
microprocess technologies to the synthesis and production of polymers. Macromol React Eng
4:543–561
61. Bally F, Serra CA, Hessel V et al (2011) Micromixer-assisted polymerization processes.
Chem Eng Sci 66:1449–1462
62. Serra CA, Chang Z (2008) Microfluidic-assisted synthesis of polymer particles. Chem Eng
Technol 31:1099–1115
63. Kakuta M, Bessoth FG, Manz A (2001) Microfabricated devices for fluid mixing and their
application for chemical synthesis. Chem Rec 1:395–405
64. Hessel V, L€ owe H, Sch€ onfeld F (2005) Micromixers – a review on passive and active mixing
principles. Chem Eng Sci 60:2479–2501
65. Ehrfeld W, Golbig K, Hessel V et al (1999) Characterization of mixing in micromixers by a
test reaction: single mixing unites and mixer arrays. Ind Eng Chem Res 38:1075–1082
66. Lu H, Schmidt MA, Jensen KF (2001) Photochemical reactions and on-line UV detection in
microfabricated reactors. Lab Chip 1:22–28
67. Ueno K, Kitagawa F, Kitamura N (2002) Photocyanation of pyrene across an oil/water
interface in a polymer microchannel. Lab Chip 2:231–234
68. Fukuyama T, Hino Y, Kamata N et al (2004) Quick execution of [2+2] type photochemical
cycloaddition reaction by continuous flow system using a glass-made microreactor. Chem
Lett 33:1430–1431
69. Maeda H, Mukae H, Mizuno K (2005) Enhanced efficiency and regioselectivity of intramolecular (2p+2p) photocycloaddition of 1-cyanonaphthalene derivative using microreactors.
Chem Lett 34:66–67
70. J€ ahnisch K, Dingerdissen U (2005) For an example of endoperoxide quenching in a continuous flow system. Chem Eng Technol 28:426–427
71. Hook BD, Dohle W, Hirst PR et al (2005) A practical flow reactor for continuous organic
photochemistry. J Org Chem 70:7558–7564
72. Matsushita Y, Kumada S, Wakabayashi K et al (2006) Photocatalytic reduction in
microreactors. Chem Lett 35:410–411
73. Sugimoto A, Sumino Y, Takagi M et al (2006) High throughput evaluation of the production
of substituted acetylenes by the Sonogashira reaction followed by the Mizoroki–Heck
reaction in ionic liquids, in situ, using a novel array reactor. Tetrahedron Lett 47:6197–6200
74. Matsushita Y, Ohba N, Suzuki T et al (2008) Photocatalytic reduction of CO 2 in a
photocatalytic microreactor under gas-liquid-solid multiphase-flow condition excited by
365-nm UV-LEDs. Catal Today 132:153–158
75. Horie T, Sumino M, Tanaka T et al (2010) Photodimerization of maleic anhydride in a
microreactor without clogging. Org Process Res Dev 14:405–410
76. Yoshida J, Kataoka K, Horcajada R et al (2008) Modern strategies in electroorganic synthesis. Chem Rev 108:2265–2299
77. Yoshida J (2009) Organic electrochemistry, microreactors, and their synergy. ECS Interface,
Summer 40–45
78. L€ owe H, Ehrfeld W (1999) State-of-the-art in microreaction technology: concepts,
manufacturing and applications. Electrochim Acta 44:3679–3689
79. Suga S, Okajima M, Fujiwara K et al (2001) “Cation flow” method. A new approach to
conventional and combinatorial organic syntheses using electrochemical microflow systems.
J Am Chem Soc 123:7941–7942
80. Kupper M, Hessel V, L€ owe H et al (2003) Micro reactor for electroorganic synthesis in the
simulated moving bed-reaction and separation environment. Electrochim Acta 48:2889–2896
81. Paddon CA, Pritchard GJ, Thiemann T et al (2002) Paired electrosynthesis: micro-flow cell
processes with and without added electrolyte. Electrochem Commun 4:825–831
42
A. Nagaki and J.-i. Yoshida