4.3 Synthesis of Molecules with Potential Materials Chemistry
Applications
4.3.1 Synthesis of Oligomers and Polymers
The application of palladium-catalyzed N-arylation reactions to the synthesis of
polymers has attracted considerable attention due to the interesting electronic
properties of these materials [6, 8, 11]. For example, polyaniline has been utilized
in anti-static materials, flexible electronics, and as electromagnetic shielding material. The first application of palladium-catalyzed amination reactions in polymer
N
N
N
NH
O
H
N
CF 3
N
N
37
F
F
O
NH
38
N
H
O
H
N
O
N
N
N
Et
40
N
O
Ph
Ph
NH
N
HN
39
N
N
H
N
N
NH
O
Me
S
N
CN
41
Fig. 9 Pharmaceutical Lead Compounds Synthesized Using Pd-Catalyzed N-Arylation as a Key Step
H
N
Pr
Me
32
N
N
OH
33
N
O
O
O
31
N
O
OH
CO 2 H
H
H
O
HO
H
35
N
N
Me
OH
CO 2
–
+
34
O
O
O
N
H
N
N
N
H
CN
OMe
OH
HO
MeO
HO
OH
OH
OH
36
Fig. 8 Natural Products Synthesized Using Pd-Catalyzed N-Arylation as a Key Step
30
G.S. Lemen and J.P. Wolfe