References
49
Sully EK, Malachowa N, Elmore BO et al. (2014) Selective chemical inhibition of agr quorum
sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance.
PLoS Pathog 10 (6):e1004174
TB Alliance and Mylan (2019) TB Alliance and Mylan announce collaboration to commercialize
pretomanid to treat tuberculosis (TB). News release 18 April 2019. https://www.eurekalert.org/
pub_releases/2019-04/b-taa041719.php. Accessed 16 December 2020
Tekin E, Beppler C, White C et al. (2016) Enhanced identification of synergistic and antagonistic
emergent interactions among three or more drugs. J R Soc Interface 13:20160332
Tekin E, White C, Kang TM et al. (2018) Prevalence and patterns of higher-order drug interactions
in Escherichia coli. NPJ Syst Biol Appl 4:31
Trombetta D, Castelli F, Sarpietro MG et al. (2005) Mechanisms of antibacterial action of three
monoterpenes. Antimicrob Agents Chemother 49 (6): 2474–2478
Tyers M, Wright GD (2019) Drug combinations: a strategy to extend the life of antibiotics in the
21st century. Nat Rev Microbiol 17 (3):141–155
Velema WA, Szymanski W, Feringa BL (2014) Photopharmacology: Beyond proof of principle. J
Am Chem Soc 136:2178–2191
Venatorx Pharmaceuticals (2020) Cefepime-Taniborbactam. https://www.venatorx.com/cefepimetaniborbactam/. Accessed 27 April 2020
Vjecha MJ, Tiberi S, Zumla A (2018) Accelerating the development of therapeutic strategies for
drug-resistant tuberculosis. Nat Rev Drug Discov 17 (9):607–608
Wang S, Setlow B, Setlow P et al. (2016) Uptake and levels of the antibiotic berberine in individual
dormant and germinating Clostridium difficile and Bacillus cereus spores as measured by laser
tweezers Raman spectroscopy. J Antimicrob Chemother 71 (6):1540–1546
Wood K, Nishida S, Sontag ED et al. (2012) Mechanism-independent method for predicting response
to multidrug combinations in bacteria. Proc Natl Acad Sci U S A 109 (30):12254–12259
Worthington RJ, Melander C (2013) Combination approaches to combat multidrug-resistant
bacteria. Trends Biotechnol 31 (3):177–184
Yang X, Ammeter D, Idowu T et al. (2019) Amphiphilic nebramine-based hybrids rescue legacy
antibiotics from intrinsic resistance in multidrug-resistant Gram-negative bacilli. Eur J Med Chem
175:187–200
York A (2020) New drugs for the antibacterial pipeline? Nat Rev Microbiol 18 (2):61–61
Zhang P (2018) Weaponizing oxygen to kill infections and disease. Paper presented at the ACS
national meeting and exposition, Boston, MA, USA, pp 19–23
Zuo GY, Li Y, Han J et al. (2012) Antibacterial and synergy of berberines with antibacterial
agents against clinical multi-drug resistant isolates of methicillin-resistant Staphylococcus aureus
(MRSA). Molecules 17 (9):10322–10330
49
Sully EK, Malachowa N, Elmore BO et al. (2014) Selective chemical inhibition of agr quorum
sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance.
PLoS Pathog 10 (6):e1004174
TB Alliance and Mylan (2019) TB Alliance and Mylan announce collaboration to commercialize
pretomanid to treat tuberculosis (TB). News release 18 April 2019. https://www.eurekalert.org/
pub_releases/2019-04/b-taa041719.php. Accessed 16 December 2020
Tekin E, Beppler C, White C et al. (2016) Enhanced identification of synergistic and antagonistic
emergent interactions among three or more drugs. J R Soc Interface 13:20160332
Tekin E, White C, Kang TM et al. (2018) Prevalence and patterns of higher-order drug interactions
in Escherichia coli. NPJ Syst Biol Appl 4:31
Trombetta D, Castelli F, Sarpietro MG et al. (2005) Mechanisms of antibacterial action of three
monoterpenes. Antimicrob Agents Chemother 49 (6): 2474–2478
Tyers M, Wright GD (2019) Drug combinations: a strategy to extend the life of antibiotics in the
21st century. Nat Rev Microbiol 17 (3):141–155
Velema WA, Szymanski W, Feringa BL (2014) Photopharmacology: Beyond proof of principle. J
Am Chem Soc 136:2178–2191
Venatorx Pharmaceuticals (2020) Cefepime-Taniborbactam. https://www.venatorx.com/cefepimetaniborbactam/. Accessed 27 April 2020
Vjecha MJ, Tiberi S, Zumla A (2018) Accelerating the development of therapeutic strategies for
drug-resistant tuberculosis. Nat Rev Drug Discov 17 (9):607–608
Wang S, Setlow B, Setlow P et al. (2016) Uptake and levels of the antibiotic berberine in individual
dormant and germinating Clostridium difficile and Bacillus cereus spores as measured by laser
tweezers Raman spectroscopy. J Antimicrob Chemother 71 (6):1540–1546
Wood K, Nishida S, Sontag ED et al. (2012) Mechanism-independent method for predicting response
to multidrug combinations in bacteria. Proc Natl Acad Sci U S A 109 (30):12254–12259
Worthington RJ, Melander C (2013) Combination approaches to combat multidrug-resistant
bacteria. Trends Biotechnol 31 (3):177–184
Yang X, Ammeter D, Idowu T et al. (2019) Amphiphilic nebramine-based hybrids rescue legacy
antibiotics from intrinsic resistance in multidrug-resistant Gram-negative bacilli. Eur J Med Chem
175:187–200
York A (2020) New drugs for the antibacterial pipeline? Nat Rev Microbiol 18 (2):61–61
Zhang P (2018) Weaponizing oxygen to kill infections and disease. Paper presented at the ACS
national meeting and exposition, Boston, MA, USA, pp 19–23
Zuo GY, Li Y, Han J et al. (2012) Antibacterial and synergy of berberines with antibacterial
agents against clinical multi-drug resistant isolates of methicillin-resistant Staphylococcus aureus
(MRSA). Molecules 17 (9):10322–10330