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Carney DW, Schmitz KR, Truong JV et al. (2014) Restriction of the conformational dynamics
of the cyclic acyldepsipeptide antibiotics improves their antibacterial activity. J Am Chem Soc
136:1922–1929
Chen H, Engkvist O (2019) Has drug design augmented by artificial intelligence become a reality?
Trends Pharmacol Sci 40 (11):806–809
Chu J, Vila-Farres X, Inoyama D et al. (2016) Discovery of MRSA active antibiotics using primary
sequence from the human microbiome. Nat Chem Biol 12 (12):1004–1006
Cockburn CL, Green RS, Damle SR et al. (2019) Functional inhibition of acid sphingomyelinase
disrupts infection by intracellular bacterial pathogens. Life Sci Alliance 2 (2):e201800292
Cohen F, Aggen JB, Andrews LD et al. (2019) Optimization of LpxC inhibitors for antibacterial
activity and cardiovascular safety. ChemMedChem 14:1560–1572
Cully M (2018) Roche taps potential antibiotics mine with Warp Drive Bio. Nat Rev Drug Discov
17:8
Culp EJ, Waglechner N, Wang W et al. (2020) Evolution-guided discovery of antibiotics that inhibit
peptidoglycan remodelling. Nature 578 (7796):582–587
Duncan LF, Wang G, Ilyichova OV et al. (2019) The fragment-based development of a benzofuran
hit as a new class of Escherichia coli DsbA inhibitors. Molecules 24 (20):3756
Elgart M, Soen Y (2018) Microbiome-germline interactions and their transgenerational implications. BioEssays 40 (4):1700018
Elnaas AR, Grice D, Han J et al. (2020) Discovery of a natural product that binds to the
Mycobacterium tuberculosis protein Rv1466 using native mass spectrometry. Molecules 25
(10):2384
Feigman MS, Kim S, Pidgeon SE et al. (2018) Synthetic immunotherapeutics against Gram-negative
pathogens. Cell Chem Biol 25 (10):1185–1194.e1185
Fer MJ, Corre LL, Pietrancosta N et al. (2018) Bacterial transferase MraY, a source of inspiration
towards new antibiotics. Curr Med Chem 25 (42):6013–6029
Feringa BL (2017) The art of building small: From molecular switches to motors (Nobel Lecture).
Angew Chem Int Ed 56 (37):11060–11078
Fischer N, Neumann P, Konevega AL et al. (2015) Structure of the E. coli ribosome–EF-Tu complex
at <3 Å resolution by Cs-corrected cryo-EM. Nature 520:567–570
Frapwell CJ, Skipp PJ, Howlin RP et al. (2020) Antimicrobial activity of the quinoline derivative
HT61 against Staphylococcus aureus biofilms. Antimicrob Agents Chemother 64 (5):e02073–
02019
Geng J, Weishuo L, Zhang Y et al. (2019) Radical polymerization inside living cells. Nat Chem
11:578–586
Gerry CJ and Schreiber SL (2020) Recent achievements and current trajectories of diversity-oriented
synthesis. Curr Opin Chem Biol 56: 1–9
Giddings L-A, Newman DJ (2015) Bioactive compounds from terrestrial extremophiles. Springer,
Cham, Switzerland, pp 1–90
González A, Fillat MF, Lanas Á (2018) Transcriptional regulators: valuable targets for novel
antibacterial strategies. Future Med Chem 10 (5):541–560
Gopal P, Dick T (2020) Targeted protein degration in antibacterial drug discovery? Prog Biophys
Mol Biol 152: 10–14
Gu S, Cui D, Chen X et al. (2018) PROTACs: An emerging targeting technique for protein
degradation in drug discovery. Bioessays 40 (4):e1700247
Gunderson CW, Segall AM (2006) DNA repair, a novel antibacterial target: Holliday junctiontrapping peptides induce DNA damage and chromosome segregation defects. Mol Microbiol 59
(4):1129–1148
Haque S, Ahmad F, Dar SA et al. (2018) Developments in strategies for quorum sensing virulence
factor inhibition to combat bacterial drug resistance. Microb Pathog 121:293–302
Hart EM, Mitchell AM, Konovalova A et al. (2019) A small-molecule inhibitor of BamA impervious
to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci 116 (43):21748