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Rineh A, Soren O, McEwan T et al. (2020) Discovery of cephalosporin-3’-diazeniumdiolates that
show dual antibacterial and antibiofilm effects against Pseudomonas aeruginosa clinical cystic
fibrosis isolates and efficacy in a murine respiratory infection model. ACS Infect Dis 6:1460–1479
Sangshetti JN, Khan FAK, Shinde DB (2015) Peptide deformylase: a new target in antibacterial,
antimalarial and anticancer drug discovery. Curr Med Chem 22 (2):214–236
Schluger NW (2013) Fluoroquinolones in the treatment of tuberculosis: which is best? Am J Respir
Crit Care Med 188 (7):768–769
Singh GS (2004) Beta-lactams in the new millennium. Part-II: cephems, oxacephems, penams and
sulbactam. Mini Rev Med Chem 4 (1):93–109
Spain M, Wong JKH, Nagalingam G et al. (2018) Antitubercular bis-substituted cyclam derivatives:
Structure–activity relationships and in vivo studies. J Med Chem 61 (8):3595–3608
Srinivasarao M, Galliford CV, Low PS (2015) Principles in the design of ligand-targeted cancer
therapeutics and imaging agents. Nat Rev Drug Discov 14 (3):203–219
Subbaiah MAM, Meanwell NA (2019) Design and tactical applications of prodrugs to enable
effective drug delivery. In: Bronson JJ (ed-in-chief) 2019 Medicinal chemistry reviews, vol 54.
ACS Division of Medicinal Chemistry, Washington, USA, pp 333–355
Swarén P, Massova I, Bellettini JR et al. (1999) Elucidation of mechanism of inhibition and X-ray
structure of the TEM-1 β-Lactamase from Escherichia coli inhibited by a N-sulfonyloxy-βlactam. J Am Chem Soc 121 (23):5353–5359
Switzer CH, Flores-Santana W, Mancardi D et al. (2009) The emergence of nitroxyl (HNO) as a
pharmacological agent. Biochim Biophys Acta Bioenerg 1787 (7):835–840
Tang M, Zhang J, Yang C et al. (2020) Gold nanoclusters for bacterial detection and infection
therapy. Front Chem 8:181
Thapa P, Li M, Bio M et al. (2016) Far-red light-activatable prodrug of paclitaxel for the combined
effects of photodynamic therapy and site-specific paclitaxel chemotherapy. J Med Chem 59
(7):3204–3214
Thompson AM, Bonnet M, Lee HH et al. (2017) Antitubercular nitroimidazoles revisited: Synthesis
and activity of the authentic 3-nitro isomer of pretomanid. ACS Med Chem Lett 8 (12):1275–1280
Velema WA, Szymanski W, Feringa BL (2014) Photopharmacology: Beyond proof of principle. J
Am Chem Soc 136:2178–2191
Verderosa AD, de la Fuente-Núñez C, Mansour SC et al. (2017) Ciprofloxacin-nitroxide hybrids
with potential for biofilm control. Eur J Med Chem 138:590–601
Wang DY, Abboud MI, Markoulides MS et al. (2016) The road to avibactam: the first clinically
useful non-β-lactam working somewhat like a β-lactam. Future Med Chem 8 (10):1063–1084
Wang W, Wang B (2018) SO 2 donors and prodrugs, and their possible applications: A review. Front
Chem 6: Article 559
Wivagg C N, Bhattacharyya R P, Hung D T (2014). Mechanisms of β-lactam killing and resistance
in the context of Mycobacterium tuberculosis. J Antibiot 67, 645–654
Wei Y, Pei D (2000) Activation of antibacterial prodrugs by peptide deformylase. Bioorg Med Chem
Lett 10 (10):1073–1076
Weiss JT, Carragher NO, Unciti-Broceta A (2015) Palladium-mediated dealkylation of N-propargylfloxuridine as a bioorthogonal oxygen-independent prodrug strategy. Sci Rep 5:9329
Wermuth CG, Ganellin CR, Lindberg P et al. (1998) Glossary of terms used in medicinal chemistry.
Pure Appl Chem 70 (5):1129–1143
Wolfe C, Pagano P, Pillar CM et al. (2018) Comparison of the in vitro antibacterial activity of
Ramizol, fidaxomicin, vancomycin, and metronidazole against 100 clinical isolates of Clostridium
difficile by broth microdilution. Diagn Microbiol Infect Dis 92 (3):250–252
Wray R, Iscla I, Kovacs Z et al. (2019) Novel compounds that specifically bind and modulate MscL:
Insights into channel gating mechanisms. FASEB J 33 (3):3180–3189
Xie L, Miller LM, Chatterjee C et al. (2004) Lacticin 481: In vitro reconstitution of lantibiotic
synthetase activity. Science 303 (5658):679–681
Yoshimura K, Batiza A, Schroeder M et al. (1999) Hydrophilicity of a single residue within MscL
correlates with increased channel mechanosensitivity. Biophys J 77 (4):1960–1972