Bioactive Compounds from Medicinal Plants in Myanmar
179
Fig. 46 Cordia
fragrantissima, known as
Sandawa or Taung-kalamet.
The bark or stem wood is
used in traditional medicine
in Myanmar
known compounds, cordiachromes A (230), B (231) [259, 260], and C (232) [261],
cordiaquinol C (233) [262], and alliodorin (234) [263] (Fig. 47). Compounds 227–
234 were obtained as racemates. These racemates exhibited leishmanicidal activity
OH
OH O
O
227 (cordiaquinol I)
OH
OH
228 (cordiaquinol J)
OH
HO
OH
OH
229 (cordiaquinol K)
R
1
R
2
232 (cordiaqchrome C) R
1 = R
2 = =O
233 (cordiaquinol C) R
1 = R
2 = OH
OH
OH
234 (alliodorin)
O
O
O
O
5
6
11
230 (cordiachrome A) D 5,6
231 (cordiachrome B) D 5,11
Fig. 47 Structures of 227–234 isolated from a methanol extract of C. fragrantissima grown in
Myanmar