A system for the dehydrogenative acetalization of three molecules of primary
alcohols promoted by [Cp*IrCl 2 ] 2 (42) and bis(pyridone)phosphine ligand L1 was
developed by Achard et al. [116] (Scheme 56).
4.3 Dehydrogenative Decarbonylation of Primary Alcohols
Madsen et al. developed a system for the dehydrogenative decarbonylation of
primary alcohols accompanied by the release of syngas (H 2 and CO) [117], showing
that this transformation is effectively promoted by [IrCl(coe) 2 ] 2 in the presence of
rac-BINAP (Scheme 57). The reaction is believed to proceed through the dehydrogenation of the primary alcohol to the corresponding aldehyde followed by its
Scheme 54 Dehydrogenative oxidation of aqueous solutions of primary alcohols to carboxylic
acids catalyzed by Ir complex 66
Scheme 55 Dehydrogenative oxidation of primary alcohols to carboxylic acids catalyzed by the Ir
complex 67
Scheme 56 Acetalization of three molecules of primary alcohols
Iridium-Catalyzed Dehydrogenative Reactions
35