above, for instance, Glaser-Tilley-type, ionic, and classical inner-sphere mechanisms, where Ir(I), Ir(III) and Ir(V) species may be formed. σ-CAM pathways that
circumvent the formation of Ir(V) intermediates have been also invoked.
Finally, owing to their synthetic versatility, selective hydrosilylation and C–H
bond silylation reactions show great promise for the functionalization of organic
molecules – where Ir catalysts may play a central role. However, intense research on
reactivity trends, substrate scope, and mechanistic understanding are still required to
improve the applicability of these methodologies.
Acknowledgements This work was supported by the “Ramón y Cajal” program (RYC201620864) (FSE/AgenciaEstatal de Investigación) (M. I.) and the Spanish Ministry of Science,
Innovation and Universities (RTI2018-099136-A-I00).
References
1. Marciniec B, Pietraszuk C, Kownacki I, Zaidlewicz M (2005) Katrizky AR, Taylor JK (eds)
Comprehensive organic functional group transformations. Elsevier, Oxford, p 941
2. Nakao Y, Hiyama T (2011) Chem Soc Rev 40:4893
3. Ojima I (1989) Patai S, Rappoport Z (eds) The chemistry of organic silicon compounds.
Wiley, New York, p 1479
4. Ojima I, Li Z, Zhu J (1998) Rappoport Z, Apeloig Y (eds) The chemistry of organic silicon
compounds. Wiley, New York, p 1687
5. Gribble GW, Li JJ (2006) Gribble GW, Li JJ (eds) Palladium in heterocyclic chemistry: a
guide for the synthetic chemist. Elsevier, Oxford, p 12
6. Fleming I, Dunogues J, Smithers R (1989) Kende AS (ed) Organic reactions, vol 2. Wiley,
New York, p 57
7. Luh TY, Liu ST (2003) Rappoport YAZ (ed) The chemistry of organic silicon compounds, vol
2. Wiley, Chichester, p 1793
8. Lam PYS, Deudon S, Averill KM, Li R, He MY, DeShong P, Clark CG (2000) J Am Chem
Soc 122:7600
9. Frihed TG, Heuckendorff M, Pedersen CM, Bols M (2012) Angew Chem Int Ed 51:12285
10. Cheng C, Hartwig JF (2014) Science 343:853
11. Ihara H, Suginome M (2009) J Am Chem Soc 131:7502
12. Tang P, Ritter T (2011) Tetrahedron 67:4449
13. Ponomarenko SA, Kirchmeyer S (2010) Muzafarov AM (ed) Silicon polymers. SpringerVerlag, Heidelberg, p 36
14. Holmes RJ, D’Andrade BW, Forrest SR, Ren X, Li J, Thompson ME (2003) Appl Phys Lett
83:3818
15. Ren X, Li J, Holmes RJ, Djurovich PI, Forrest SR, Thompson ME (2004) Chem Mater
16:4743
16. Bin JK, Cho NS, Hong JI (2012) Adv Mater 24:2911
17. Lin JJ, Liao WS, Huang HJ, Wu FI, Cheng CH (2008) Adv Funct Mater 18:485
18. Tsai MH, Lin HW, Su HC, Ke TH, Wu CC, Fang FC, Liao YL, Wong KT, Wu CI (2006) Adv
Mater 18:1216
19. Leung MK, Yang WH, Chuang CN, Lee JH, Lin CH, Wei MK, Liu YH (2012) Org Lett
14:4986
20. Han WS, Son HJ, Wee KR, Min KT, Kwon S, Suh IH, Choi SH, Jung DH, Kang SO (2009) J
Phys Chem C 113:19686
266
M. Iglesias and L. A. Oro
circumvent the formation of Ir(V) intermediates have been also invoked.
Finally, owing to their synthetic versatility, selective hydrosilylation and C–H
bond silylation reactions show great promise for the functionalization of organic
molecules – where Ir catalysts may play a central role. However, intense research on
reactivity trends, substrate scope, and mechanistic understanding are still required to
improve the applicability of these methodologies.
Acknowledgements This work was supported by the “Ramón y Cajal” program (RYC201620864) (FSE/AgenciaEstatal de Investigación) (M. I.) and the Spanish Ministry of Science,
Innovation and Universities (RTI2018-099136-A-I00).
References
1. Marciniec B, Pietraszuk C, Kownacki I, Zaidlewicz M (2005) Katrizky AR, Taylor JK (eds)
Comprehensive organic functional group transformations. Elsevier, Oxford, p 941
2. Nakao Y, Hiyama T (2011) Chem Soc Rev 40:4893
3. Ojima I (1989) Patai S, Rappoport Z (eds) The chemistry of organic silicon compounds.
Wiley, New York, p 1479
4. Ojima I, Li Z, Zhu J (1998) Rappoport Z, Apeloig Y (eds) The chemistry of organic silicon
compounds. Wiley, New York, p 1687
5. Gribble GW, Li JJ (2006) Gribble GW, Li JJ (eds) Palladium in heterocyclic chemistry: a
guide for the synthetic chemist. Elsevier, Oxford, p 12
6. Fleming I, Dunogues J, Smithers R (1989) Kende AS (ed) Organic reactions, vol 2. Wiley,
New York, p 57
7. Luh TY, Liu ST (2003) Rappoport YAZ (ed) The chemistry of organic silicon compounds, vol
2. Wiley, Chichester, p 1793
8. Lam PYS, Deudon S, Averill KM, Li R, He MY, DeShong P, Clark CG (2000) J Am Chem
Soc 122:7600
9. Frihed TG, Heuckendorff M, Pedersen CM, Bols M (2012) Angew Chem Int Ed 51:12285
10. Cheng C, Hartwig JF (2014) Science 343:853
11. Ihara H, Suginome M (2009) J Am Chem Soc 131:7502
12. Tang P, Ritter T (2011) Tetrahedron 67:4449
13. Ponomarenko SA, Kirchmeyer S (2010) Muzafarov AM (ed) Silicon polymers. SpringerVerlag, Heidelberg, p 36
14. Holmes RJ, D’Andrade BW, Forrest SR, Ren X, Li J, Thompson ME (2003) Appl Phys Lett
83:3818
15. Ren X, Li J, Holmes RJ, Djurovich PI, Forrest SR, Thompson ME (2004) Chem Mater
16:4743
16. Bin JK, Cho NS, Hong JI (2012) Adv Mater 24:2911
17. Lin JJ, Liao WS, Huang HJ, Wu FI, Cheng CH (2008) Adv Funct Mater 18:485
18. Tsai MH, Lin HW, Su HC, Ke TH, Wu CC, Fang FC, Liao YL, Wong KT, Wu CI (2006) Adv
Mater 18:1216
19. Leung MK, Yang WH, Chuang CN, Lee JH, Lin CH, Wei MK, Liu YH (2012) Org Lett
14:4986
20. Han WS, Son HJ, Wee KR, Min KT, Kwon S, Suh IH, Choi SH, Jung DH, Kang SO (2009) J
Phys Chem C 113:19686
266
M. Iglesias and L. A. Oro