267
Sun, X., Jiang, R., Przepiorski, A., Reddy, S., Palmano, K. P., & Krissansen, G. W. (2012). “Ironsaturated” bovine lactoferrin improves the chemotherapeutic effects of tamoxifen in the treatment of basal-like breast cancer in mice. BMC Cancer, 12(1), 591.
Sultan, S., Huma, N., Butt, M. S., Aleem, M., & Abbas, M. (2017). Therapeutic potential of
dairy bioactive peptides: A contemporary perspective. Critical Reviews in Food Science and
Nutrition, 58(1), 105–115.
Tagliazucchi, D., Shamsia, S., & Conte, A. (2016). Release of angiotensin converting enzymeinhibitory peptides during in vitro gastro-intestinal digestion of camel milk. International
Dairy Journal, 56, 119–128.
Teschemacher, H. (2003). Opioid receptor ligands derived from food proteins. Current
Pharmaceutical Design, 9(16), 1331–1344.
Thundimadathil, J. (2012). Cancer treatment using peptides: Current therapies and future prospects. Journal of Amino Acids, 2012, 1.
Tomita, M., Bellamy, W., Takase, M., Yamauchi, K., Wakabayashi, H., & Kawase, K. (1991).
Potent antibacterial peptides generated by pepsin digestion of bovine lactoferrin. Journal of
Dairy Science, 74(12), 4137–4142.
Tulipano, G., Sibilia, V., Caroli, A. M., & Cocchi, D. (2011). Whey proteins as source of dipeptidyl
dipeptidase IV (dipeptidyl peptidase-4) inhibitors. Peptides, 32, 835–838.
Tyagi, A., Tuknait, A., Anand, P., Gupta, S., Sharma, M., Mathur, D., … Raghava, G. P. (2014).
CancerPPD: A database of anticancer peptides and proteins. Nucleic Acids Research, 43(D1),
D837–D843.
Uchida, M., Ohshiba, Y., & Mogami, O. (2011). Novel dipeptidyl peptidase-4-inhibiting peptide
derived from b-lactoglobulin. Journal of Pharmacological Sciences, 117, 63–66.
Udenigwe, C. C., & Aluko, R. E. (2012). Food protein‐derived bioactive peptides: production,
processing, and potential health benefits. Journal of Food Science, 77(1), R11–R24.
Vankudre, M., Balpande, A., & Athale, M. (2015). Comparative analysis of α-amylase inhibition
and antioxidant activity of whey from cow and buffalo milk fermented with Lactobacillus species. Bioscience Biotechnology Research Communications, 8(1), 25–28.
Vermeirssen, V., Van Camp, J., & Verstraete, W. (2004). Bioavailability of angiotensin I converting
enzyme inhibitory peptides. British Journal of Nutrition, 92(3), 357–366.
Wakabayashi, H., Takase, M., & Tomita, M. (2003). Lactoferricin derived from milk protein lactoferrin. Current Pharmaceutical Design, 9(16), 1277–1287.
Wang, W., Gu, F., Wei, C., Tang, Y., Zheng, X., Ren, M., & Qin, Y. (2013). PGPIPN, a therapeutic
hexapeptide, suppressed human ovarian cancer growth by targeting BCL2. PLoS One, 8(4),
e60701.
Xu, R. J. (1998). Bioactive peptides in milk and their biological and health implications. Food
Reviews International, 14(1), 1–16.
Xu, X. X., Jiang, H. R., Li, H. B., Zhang, T. N., Zhou, Q., & Liu, N. (2010). Apoptosis of stomach cancer cell SGC-7901 and regulation of Akt signaling way induced by bovine lactoferrin.
Journal of Dairy Science, 93(6), 2344–2350.
Yamamoto, N., Maeno, M., & Takano, T. (1999). Purification and characterization of an antihypertensive peptide from a yogurt-like product fermented by Lactobacillus helveticus CPN4.
Journal of Dairy Science, 82(7), 1388–1393.
Yoo, Y. C., Watanabe, R., Koike, Y., Mitobe, M., Shimazaki, K. I., Watanabe, S., & Azuma, I.
(1997). Apoptosis in human leukemic cells induced by lactoferricin, a bovine milk proteinderived peptide: Involvement of reactive oxygen species. Biochemical and Biophysical
Research Communications, 237(3), 624–628.
Yoshikawa, M. (2015). Bioactive peptides derived from natural proteins with respect to diversity
of their receptors and physiological effects. Peptides, 72, 208–225.
Zhang, Y., Lima, C. F., & Rodrigues, L. R. (2014). Anticancer effects of lactoferrin: Underlying
mechanisms and future trends in cancer therapy. Nutrition Reviews, 72(12), 763–773.
Zhang, Y., Lima, C. F., & Rodrigues, L. R. (2015). In vitro evaluation of bovine lactoferrin potential as an anticancer agent. International Dairy Journal, 40, 6–15.
Nutraceutical Properties of Bioactive Peptides
Sun, X., Jiang, R., Przepiorski, A., Reddy, S., Palmano, K. P., & Krissansen, G. W. (2012). “Ironsaturated” bovine lactoferrin improves the chemotherapeutic effects of tamoxifen in the treatment of basal-like breast cancer in mice. BMC Cancer, 12(1), 591.
Sultan, S., Huma, N., Butt, M. S., Aleem, M., & Abbas, M. (2017). Therapeutic potential of
dairy bioactive peptides: A contemporary perspective. Critical Reviews in Food Science and
Nutrition, 58(1), 105–115.
Tagliazucchi, D., Shamsia, S., & Conte, A. (2016). Release of angiotensin converting enzymeinhibitory peptides during in vitro gastro-intestinal digestion of camel milk. International
Dairy Journal, 56, 119–128.
Teschemacher, H. (2003). Opioid receptor ligands derived from food proteins. Current
Pharmaceutical Design, 9(16), 1331–1344.
Thundimadathil, J. (2012). Cancer treatment using peptides: Current therapies and future prospects. Journal of Amino Acids, 2012, 1.
Tomita, M., Bellamy, W., Takase, M., Yamauchi, K., Wakabayashi, H., & Kawase, K. (1991).
Potent antibacterial peptides generated by pepsin digestion of bovine lactoferrin. Journal of
Dairy Science, 74(12), 4137–4142.
Tulipano, G., Sibilia, V., Caroli, A. M., & Cocchi, D. (2011). Whey proteins as source of dipeptidyl
dipeptidase IV (dipeptidyl peptidase-4) inhibitors. Peptides, 32, 835–838.
Tyagi, A., Tuknait, A., Anand, P., Gupta, S., Sharma, M., Mathur, D., … Raghava, G. P. (2014).
CancerPPD: A database of anticancer peptides and proteins. Nucleic Acids Research, 43(D1),
D837–D843.
Uchida, M., Ohshiba, Y., & Mogami, O. (2011). Novel dipeptidyl peptidase-4-inhibiting peptide
derived from b-lactoglobulin. Journal of Pharmacological Sciences, 117, 63–66.
Udenigwe, C. C., & Aluko, R. E. (2012). Food protein‐derived bioactive peptides: production,
processing, and potential health benefits. Journal of Food Science, 77(1), R11–R24.
Vankudre, M., Balpande, A., & Athale, M. (2015). Comparative analysis of α-amylase inhibition
and antioxidant activity of whey from cow and buffalo milk fermented with Lactobacillus species. Bioscience Biotechnology Research Communications, 8(1), 25–28.
Vermeirssen, V., Van Camp, J., & Verstraete, W. (2004). Bioavailability of angiotensin I converting
enzyme inhibitory peptides. British Journal of Nutrition, 92(3), 357–366.
Wakabayashi, H., Takase, M., & Tomita, M. (2003). Lactoferricin derived from milk protein lactoferrin. Current Pharmaceutical Design, 9(16), 1277–1287.
Wang, W., Gu, F., Wei, C., Tang, Y., Zheng, X., Ren, M., & Qin, Y. (2013). PGPIPN, a therapeutic
hexapeptide, suppressed human ovarian cancer growth by targeting BCL2. PLoS One, 8(4),
e60701.
Xu, R. J. (1998). Bioactive peptides in milk and their biological and health implications. Food
Reviews International, 14(1), 1–16.
Xu, X. X., Jiang, H. R., Li, H. B., Zhang, T. N., Zhou, Q., & Liu, N. (2010). Apoptosis of stomach cancer cell SGC-7901 and regulation of Akt signaling way induced by bovine lactoferrin.
Journal of Dairy Science, 93(6), 2344–2350.
Yamamoto, N., Maeno, M., & Takano, T. (1999). Purification and characterization of an antihypertensive peptide from a yogurt-like product fermented by Lactobacillus helveticus CPN4.
Journal of Dairy Science, 82(7), 1388–1393.
Yoo, Y. C., Watanabe, R., Koike, Y., Mitobe, M., Shimazaki, K. I., Watanabe, S., & Azuma, I.
(1997). Apoptosis in human leukemic cells induced by lactoferricin, a bovine milk proteinderived peptide: Involvement of reactive oxygen species. Biochemical and Biophysical
Research Communications, 237(3), 624–628.
Yoshikawa, M. (2015). Bioactive peptides derived from natural proteins with respect to diversity
of their receptors and physiological effects. Peptides, 72, 208–225.
Zhang, Y., Lima, C. F., & Rodrigues, L. R. (2014). Anticancer effects of lactoferrin: Underlying
mechanisms and future trends in cancer therapy. Nutrition Reviews, 72(12), 763–773.
Zhang, Y., Lima, C. F., & Rodrigues, L. R. (2015). In vitro evaluation of bovine lactoferrin potential as an anticancer agent. International Dairy Journal, 40, 6–15.
Nutraceutical Properties of Bioactive Peptides