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ERK phosphorylation and AMPK-dependent inhibition of GSK-3β. Toxicol Appl Pharmacol
307:138
318. Taher M, Amiroudine MZAM, Jaffri JM, Amri MS, Susanti D, Abd Hamid S, Rezali MF,
Hassan CM, Read RW, Ahmed Q, Ahmad F (2017) A lignan with glucose uptake activity in
3T3-L1 adipocytes from the stem bark of Knema patentinervia. Pak J Pharm Sci 30:1335
319. Zeng W, Yao C-P, Xu P-S, Zhang G-G, Liu Z-Q, Xu K-P, Zou Z-X, Tan G-S (2017) A new
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320. Ridley RG, Fairlamb AH, Vial HJ (eds) (2003) Drugs against parasitic diseases: R&D
methodologies and issues. TDR (WHO ref. no. TDR/PRD 03.1)
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322. World Health Organization (2000) WHO report on global surveillance of epidemic-prone
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324. Bruschi F, Gradoni L(eds) (2018) The leishmaniases: old neglected tropical diseases. Springer
International Publishers, Cham, Switzerland
325. Foster S, Phillips M (1998) Economics and its contribution to the fight against malaria. Ann
Trop Med Parasitol 92:391
326. Houghton PJ (1991) Investigation of plants used in traditional medicine. Int Pharm J 5:29
327. Hofheinz W, Merkli B (1991) Quinine and quinine analogs. Antimalarial drug II. In Peters W,
Richard WHG (eds) Current antimalarial and new drug development. Springer, Heidelberg,
New York, and Tokyo
328. Meshnick SR, Thomas A, Ranz A, Xu C-M, Pan H-Z (1991) Artemisinin (qinghaosu): the
role of intracellular hemin in its mechanism of antimalarial action. Mol Biochem Parasitol
49:181
329. White NJ (1998) Preventing antimalarial drug resistance through combinations. Drug Resist
Updat 1:3
330. World Health Organization, Malaria Unit, Division of Control of Tropical Diseases, Consultation R of JCI (1998) The use of artemisinin and its derivatives as antimalarial drugs. https://
www.who.int/malaria/publications/atoz/who_mal_98_1086/en/
331. Kirchhoff LV (1993) American trypanosomiasis (Chagas’ disease)—a tropical disease now
in the United States. N Engl J Med 329:639
332. de Andrade AL, Zicker F, de Oliveira RM, Almeiida Silva S, Luquetti A, Travassos LR,
Almeida IC, de Andrade SS, de Andrade JG, Martelli CM (1996) Randomised trial of efficacy
of benznidazole in treatment of early Trypanosoma cruzi infection. Lancet 348:1407
333. Rodrigues JCF, Godinho JLP, de Souza W (2014) Biology of human pathogenic trypanosomatids: epidemiology, lifecyle and ultrastructure. In: Santos A, Branquinha M, d’AvilaLevy C, Kneipp L, Sodré (eds) Proteins and proteinomics of Leishmania and Trypanosoma.
Subcellular biochemistry, vol 74. Springer, Dordrecht, p 1
334. World Health Organization (1995) The current global situation of the HIV/AIDS pandemic.
Wkly Epidemiol Rec 70:355
335. World Health Organization (2000) The leishmaniasis. Technical report series. https://apps.
who.int/iris/bitstream/handle/10665/44412/WHO_TRS_949_eng.pdf?sequence=1
336. Bastos JK, Albuquerque S, Silva ML (1999) Evaluation of the trypanocidal activity of lignans
isolated from the leaves of Zanthoxylum naranjillo. Planta Med 65:541
337. Ribeiro A, Piló-Veloso D, Romanha AJ, Zani CL (1997) Trypanocidal flavonoids from Trixis
vauthieri. J Nat Prod 60:836
338. Souza DHF, Garratt RC, Araújo APU, Guimaraes BG, Jesus WDP, Michels PAM, Hannaert V,
Oliva G (1998) Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase:
structure, catalytic mechanism and targeted inhibitor design. FEBS Lett 424:131
J. Pospíšil et al.
317. Song J-S, Kim E-K, Choi Y-W, Oh WK, Kim Y-M (2016) Hepatocyte-protective effect
of nectandrin B, a nutmeg lignan, against oxidative stress: role of Nrf2 activation through
ERK phosphorylation and AMPK-dependent inhibition of GSK-3β. Toxicol Appl Pharmacol
307:138
318. Taher M, Amiroudine MZAM, Jaffri JM, Amri MS, Susanti D, Abd Hamid S, Rezali MF,
Hassan CM, Read RW, Ahmed Q, Ahmad F (2017) A lignan with glucose uptake activity in
3T3-L1 adipocytes from the stem bark of Knema patentinervia. Pak J Pharm Sci 30:1335
319. Zeng W, Yao C-P, Xu P-S, Zhang G-G, Liu Z-Q, Xu K-P, Zou Z-X, Tan G-S (2017) A new
neolignan from Selaginella moellendorffii Hieron. Nat Prod Res 31:2223
320. Ridley RG, Fairlamb AH, Vial HJ (eds) (2003) Drugs against parasitic diseases: R&D
methodologies and issues. TDR (WHO ref. no. TDR/PRD 03.1)
321. Fournet A, Munoz V (2005) Natural products as trypanocidal, antileishmanial, and antimalarial drugs. Curr Top Med Chem 2:1215
322. World Health Organization (2000) WHO report on global surveillance of epidemic-prone
infectious diseases. https://www.who.int/csr/resources/publications/surveillance/WHO_
CDS_CSR_ISR_2000_1/en/
323. World Health Organization (2010) Control of the leishmaniases. Report of a meeting of the
WHO expert committee on the control of leishmaniases, Geneva, 22–26 March 2010. In:
WHO Tech. Rep. Ser. https://apps.who.int/iris/handle/10665/44412
324. Bruschi F, Gradoni L(eds) (2018) The leishmaniases: old neglected tropical diseases. Springer
International Publishers, Cham, Switzerland
325. Foster S, Phillips M (1998) Economics and its contribution to the fight against malaria. Ann
Trop Med Parasitol 92:391
326. Houghton PJ (1991) Investigation of plants used in traditional medicine. Int Pharm J 5:29
327. Hofheinz W, Merkli B (1991) Quinine and quinine analogs. Antimalarial drug II. In Peters W,
Richard WHG (eds) Current antimalarial and new drug development. Springer, Heidelberg,
New York, and Tokyo
328. Meshnick SR, Thomas A, Ranz A, Xu C-M, Pan H-Z (1991) Artemisinin (qinghaosu): the
role of intracellular hemin in its mechanism of antimalarial action. Mol Biochem Parasitol
49:181
329. White NJ (1998) Preventing antimalarial drug resistance through combinations. Drug Resist
Updat 1:3
330. World Health Organization, Malaria Unit, Division of Control of Tropical Diseases, Consultation R of JCI (1998) The use of artemisinin and its derivatives as antimalarial drugs. https://
www.who.int/malaria/publications/atoz/who_mal_98_1086/en/
331. Kirchhoff LV (1993) American trypanosomiasis (Chagas’ disease)—a tropical disease now
in the United States. N Engl J Med 329:639
332. de Andrade AL, Zicker F, de Oliveira RM, Almeiida Silva S, Luquetti A, Travassos LR,
Almeida IC, de Andrade SS, de Andrade JG, Martelli CM (1996) Randomised trial of efficacy
of benznidazole in treatment of early Trypanosoma cruzi infection. Lancet 348:1407
333. Rodrigues JCF, Godinho JLP, de Souza W (2014) Biology of human pathogenic trypanosomatids: epidemiology, lifecyle and ultrastructure. In: Santos A, Branquinha M, d’AvilaLevy C, Kneipp L, Sodré (eds) Proteins and proteinomics of Leishmania and Trypanosoma.
Subcellular biochemistry, vol 74. Springer, Dordrecht, p 1
334. World Health Organization (1995) The current global situation of the HIV/AIDS pandemic.
Wkly Epidemiol Rec 70:355
335. World Health Organization (2000) The leishmaniasis. Technical report series. https://apps.
who.int/iris/bitstream/handle/10665/44412/WHO_TRS_949_eng.pdf?sequence=1
336. Bastos JK, Albuquerque S, Silva ML (1999) Evaluation of the trypanocidal activity of lignans
isolated from the leaves of Zanthoxylum naranjillo. Planta Med 65:541
337. Ribeiro A, Piló-Veloso D, Romanha AJ, Zani CL (1997) Trypanocidal flavonoids from Trixis
vauthieri. J Nat Prod 60:836
338. Souza DHF, Garratt RC, Araújo APU, Guimaraes BG, Jesus WDP, Michels PAM, Hannaert V,
Oliva G (1998) Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase:
structure, catalytic mechanism and targeted inhibitor design. FEBS Lett 424:131