Role of Active Complexes of Selected
Thiopurine Derivatives with Bi(III) Ions
Related to Kinetics and Mechanism
of the Electrode Process in the Surfactant
Presence
Agnieszka Nosal-Wierci ´
nska and Waldemar Kaliszczak
1 Introduction
The development of industry, environmental degradation, and specific lifestyle of
man led to the emergence of a new phenomenon which is civilization diseases.
Among them, cancer, which is often difficult to diagnose and treat, is essential. One
of the methods of systemic treatment is chemotherapy, based on drugs that affect the
cell cycle, which causes it to be toxic to the whole body. There is therefore a need
to study the mechanisms of these drugs’ actions and to search for new systems of
controlled release of drugs.
Modern electrochemistry gives such possibilities, for example, by undertaking
the problem of testing electrode mechanisms, including multi-electron complex
processes, in which there are intermediate stages leading to the creation of the
product. The kinetics of these processes is largely dependent on the structure of
the electrical double layer, which is conditioned by the phenomenon of adsorption,
among others [1–4].
Studies of electroreduction processes of many depolarizers in the presence of
organic substances show significant differences in the kinetics and mechanism of
electrode processes [5–9]. The criteria to be met by the depolarizer/basic electrolyte/organic substance system show that the electrode processes can be accelerated by these substances (“cap-pair” rule) and point out to the mechanism of these
A. Nosal-Wierci´ nska (B) · W. Kaliszczak
Faculty of Chemistry, Department of Analytical Chemistry, Institute of Chemical Sciences, Maria
Curie Skłodowska University, M. Curie-Sklodowska Sq. 3, 20-031 Lublin, Poland
e-mail: anosal@poczta.umcs.lublin.pl
© Springer Nature Switzerland AG 2021
O. Fesenko and L. Yatsenko (eds.), Nanomaterials and Nanocomposites,
Nanostructure Surfaces, and Their Applications, Springer Proceedings
in Physics 246, https://doi.org/10.1007/978-3-030-51905-6_36
523
Thiopurine Derivatives with Bi(III) Ions
Related to Kinetics and Mechanism
of the Electrode Process in the Surfactant
Presence
Agnieszka Nosal-Wierci ´
nska and Waldemar Kaliszczak
1 Introduction
The development of industry, environmental degradation, and specific lifestyle of
man led to the emergence of a new phenomenon which is civilization diseases.
Among them, cancer, which is often difficult to diagnose and treat, is essential. One
of the methods of systemic treatment is chemotherapy, based on drugs that affect the
cell cycle, which causes it to be toxic to the whole body. There is therefore a need
to study the mechanisms of these drugs’ actions and to search for new systems of
controlled release of drugs.
Modern electrochemistry gives such possibilities, for example, by undertaking
the problem of testing electrode mechanisms, including multi-electron complex
processes, in which there are intermediate stages leading to the creation of the
product. The kinetics of these processes is largely dependent on the structure of
the electrical double layer, which is conditioned by the phenomenon of adsorption,
among others [1–4].
Studies of electroreduction processes of many depolarizers in the presence of
organic substances show significant differences in the kinetics and mechanism of
electrode processes [5–9]. The criteria to be met by the depolarizer/basic electrolyte/organic substance system show that the electrode processes can be accelerated by these substances (“cap-pair” rule) and point out to the mechanism of these
A. Nosal-Wierci´ nska (B) · W. Kaliszczak
Faculty of Chemistry, Department of Analytical Chemistry, Institute of Chemical Sciences, Maria
Curie Skłodowska University, M. Curie-Sklodowska Sq. 3, 20-031 Lublin, Poland
e-mail: anosal@poczta.umcs.lublin.pl
© Springer Nature Switzerland AG 2021
O. Fesenko and L. Yatsenko (eds.), Nanomaterials and Nanocomposites,
Nanostructure Surfaces, and Their Applications, Springer Proceedings
in Physics 246, https://doi.org/10.1007/978-3-030-51905-6_36
523