Chapter 9
Polymeric Composite Films
with Controlled Release of Natural
Antioxidant Enoxil
Roman Kozakevych, Yulia Bolbukh, Lucian Lupascu, Tudor Lupascu,
and Valentin Tertykh
9.1 Introduction
Among the biologically active plant compounds, one of the first places in the
prevalence is polyphenols, which are an outstanding source of variety of compounds
with extraordinary diverse composition [1, 2]. Several thousand molecules having a
polyphenol structure have been identified in higher plants. These compounds may
be classified into different groups as a function of the number of phenol rings that
they contain and of the structural elements that bind these rings to one another. The
polyphenols fall into the following types of chemical substances: phenolic acids,
flavonoids, stilbenes, lignans, catechins, etc.
In addition, residual materials containing polyphenols are widely available,
which is why it is a very attractive subject for study. Recent interest in food polyphenols has increased greatly, owing to their antioxidant capacity [3] (free radical
scavenging and metal chelating activities) and possible beneficial implications in
human health, such as in the treatment and prevention of cancer, cardiovascular
disease, and Ãntimicrobial activity [4–6].
As is well known, the disruption of normal levels of free radicals and reactive
oxygen species causes damage to organs and tissues [7]. That will, in turn, contribute
to the decreased immunity and a number of infectious diseases. The inflammatory
process is a normal reaction of the mucosa to infection, which usually leads to the
destruction of pathogens. However, the long-term presence of highly active cells
and free radicals in the area of inflammation leads to an uncontrolled reaction and
R. Kozakevych () · Y. Bolbukh · V. Tertykh
Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine
L. Lupascu · T. Lupascu
Institute of Chemistry of the Academy of Sciences of Moldova, Chisinau, Republic of Moldova
© Springer International Publishing AG, part of Springer Nature 2018
O. Fesenko, L. Yatsenko (eds.), Nanochemistry, Biotechnology, Nanomaterials,
and Their Applications, Springer Proceedings in Physics 214,
https://doi.org/10.1007/978-3-319-92567-7_9
149
Polymeric Composite Films
with Controlled Release of Natural
Antioxidant Enoxil
Roman Kozakevych, Yulia Bolbukh, Lucian Lupascu, Tudor Lupascu,
and Valentin Tertykh
9.1 Introduction
Among the biologically active plant compounds, one of the first places in the
prevalence is polyphenols, which are an outstanding source of variety of compounds
with extraordinary diverse composition [1, 2]. Several thousand molecules having a
polyphenol structure have been identified in higher plants. These compounds may
be classified into different groups as a function of the number of phenol rings that
they contain and of the structural elements that bind these rings to one another. The
polyphenols fall into the following types of chemical substances: phenolic acids,
flavonoids, stilbenes, lignans, catechins, etc.
In addition, residual materials containing polyphenols are widely available,
which is why it is a very attractive subject for study. Recent interest in food polyphenols has increased greatly, owing to their antioxidant capacity [3] (free radical
scavenging and metal chelating activities) and possible beneficial implications in
human health, such as in the treatment and prevention of cancer, cardiovascular
disease, and Ãntimicrobial activity [4–6].
As is well known, the disruption of normal levels of free radicals and reactive
oxygen species causes damage to organs and tissues [7]. That will, in turn, contribute
to the decreased immunity and a number of infectious diseases. The inflammatory
process is a normal reaction of the mucosa to infection, which usually leads to the
destruction of pathogens. However, the long-term presence of highly active cells
and free radicals in the area of inflammation leads to an uncontrolled reaction and
R. Kozakevych () · Y. Bolbukh · V. Tertykh
Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine
L. Lupascu · T. Lupascu
Institute of Chemistry of the Academy of Sciences of Moldova, Chisinau, Republic of Moldova
© Springer International Publishing AG, part of Springer Nature 2018
O. Fesenko, L. Yatsenko (eds.), Nanochemistry, Biotechnology, Nanomaterials,
and Their Applications, Springer Proceedings in Physics 214,
https://doi.org/10.1007/978-3-319-92567-7_9
149