108
57. Becker J, Rohles CM, Wittmann C (2018) Metabolically engineered Corynebacterium glutamicum for bio-based production of chemicals, fuels, materials, and healthcare products.
Metab Eng 50:122–141
58. Otten A, Brocker M, Bott M (2015) Metabolic engineering of Corynebacterium glutamicum
for the production of itaconate. Metab Eng 30:156–165
59. Markham KA, Alper HS (2018) Synthetic biology expands the industrial potential of
Yarrowia lipolytica. Trends Biotechnol 36(10):1085–1095
60. Blazeck J, Hill A, Jamoussi M, Pan A, Miller J, Alper HS (2015) Metabolic engineering of
Yarrowia lipolytica for itaconic acid production. Metab Eng 32:66–73
61. Zhao C, Cui Z, Zhao X, Zhang J, Zhang L, Tian Y, Qi Q, Liu J (2019) Enhanced itaconic acid
production in Yarrowia lipolytica via heterologous expression of a mitochondrial transporter
MTT. Appl Microbiol Biotechnol 103(5):2181–2192
62. Kwak S, Jin Y-S (2017) Production of fuels and chemicals from xylose by engineered
Saccharomyces cerevisiae: a review and perspective. Microb Cell Fact 16(1):82
63. Blazeck J, Miller J, Pan A, Gengler J, Holden C, Jamoussi M, Alper HS (2014) Metabolic
engineering of Saccharomyces cerevisiae for itaconic acid production. Appl Microbiol
Biotechnol 98(19):8155–8164
64. Young EM, Zhao Z, Gielesen BEM, Wu L, Benjamin Gordon D, Roubos JA, Voigt CA (2018)
Iterative algorithm-guided design of massive strain libraries, applied to itaconic acid production in yeast. Metab Eng 48:33–43
65. Levinson WE, Kurtzman CP, Kuo TM (2006) Production of itaconic acid by Pseudozyma
Antarctica NRRL Y-7808 under nitrogen-limited growth conditions. Enzyme Microb Technol
39(4):824–827
66. Tabuchi T, Sugisawa T, Ishidori T, Nakahara T, Sugiyama J (1981) Itaconic acid fermentation
by a yeast belonging to the genus Candida. Agric Biol Chem 45(2):475–479
67. Petruccioli M, Pulci V, Federici F (1999) Itaconic acid production by Aspergillus terreus on
raw starchy materials. Lett Appl Microbiol 28(4):309–312
68. Mondala AH (2015) Direct fungal fermentation of lignocellulosic biomass into itaconic, fumaric, and malic acids: current and future prospects. J Ind Microbiol Biotechnol
42(4):487–506
69. Yahiro K, Shibata S, Jia S-R, Park Y, Okabe M (1997) Efficient itaconic acid production from
raw corn starch. J Ferment Bioeng 84(4):375–377
70. Reddy CSK, Singh RP (2002) Enhanced production of itaconic acid from corn starch and
market refuse fruits by genetically manipulated Aspergillus terreus SKR10. Bioresour
Technol 85(1):69–71
71. Bafana R, Sivanesan S, Pandey RA (2017) Itaconic acid production by filamentous Fungi in
starch-rich industrial residues. Indian J Microbiol 57(3):322–328
72. Bafana R, Sivanesan S, Pandey R (2019) Optimization and scale up of itaconic acid production from potato starch waste in stirred tank bioreactor. Biotechnol Prog 35
73. Okamoto S, Chin T, Nagata K, Takahashi T, Ohara H, Aso Y (2015) Production of itaconic
acid in Escherichia coli expressing recombinant α-amylase using starch as substrate. J Biosci
Bioeng 119(5):548–553
74. Gnanasekaran R, Dhandapani B, Gopinath KP, Iyyappan J (2018a) Synthesis of itaconic
acid from agricultural waste using novel Aspergillus niveus. Prep Biochem Biotechnol
48(7):605–609
75. Petridis L, Smith JC (2018) Molecular-level driving forces in lignocellulosic biomass deconstruction for bioenergy. Nat Rev Chem 2(11):382–389
76. Kautola H (1990) Itaconic acid production from xylose in repeated-batch and continuous
bioreactors. Appl Microbiol Biotechnol 33(1):7–11
77. Saha BC, Kennedy GJ (2017) Mannose and galactose as substrates for production of itaconic
acid by Aspergillus terreus. Lett Appl Microbiol 65(6):527–533
78. Krull S, Eidt L, Hevekerl A, Kuenz A, Prüße U (2017) Itaconic acid production from wheat
chaff by Aspergillus terreus. Process Biochem 63:169–176
K. Avasthi et al.
57. Becker J, Rohles CM, Wittmann C (2018) Metabolically engineered Corynebacterium glutamicum for bio-based production of chemicals, fuels, materials, and healthcare products.
Metab Eng 50:122–141
58. Otten A, Brocker M, Bott M (2015) Metabolic engineering of Corynebacterium glutamicum
for the production of itaconate. Metab Eng 30:156–165
59. Markham KA, Alper HS (2018) Synthetic biology expands the industrial potential of
Yarrowia lipolytica. Trends Biotechnol 36(10):1085–1095
60. Blazeck J, Hill A, Jamoussi M, Pan A, Miller J, Alper HS (2015) Metabolic engineering of
Yarrowia lipolytica for itaconic acid production. Metab Eng 32:66–73
61. Zhao C, Cui Z, Zhao X, Zhang J, Zhang L, Tian Y, Qi Q, Liu J (2019) Enhanced itaconic acid
production in Yarrowia lipolytica via heterologous expression of a mitochondrial transporter
MTT. Appl Microbiol Biotechnol 103(5):2181–2192
62. Kwak S, Jin Y-S (2017) Production of fuels and chemicals from xylose by engineered
Saccharomyces cerevisiae: a review and perspective. Microb Cell Fact 16(1):82
63. Blazeck J, Miller J, Pan A, Gengler J, Holden C, Jamoussi M, Alper HS (2014) Metabolic
engineering of Saccharomyces cerevisiae for itaconic acid production. Appl Microbiol
Biotechnol 98(19):8155–8164
64. Young EM, Zhao Z, Gielesen BEM, Wu L, Benjamin Gordon D, Roubos JA, Voigt CA (2018)
Iterative algorithm-guided design of massive strain libraries, applied to itaconic acid production in yeast. Metab Eng 48:33–43
65. Levinson WE, Kurtzman CP, Kuo TM (2006) Production of itaconic acid by Pseudozyma
Antarctica NRRL Y-7808 under nitrogen-limited growth conditions. Enzyme Microb Technol
39(4):824–827
66. Tabuchi T, Sugisawa T, Ishidori T, Nakahara T, Sugiyama J (1981) Itaconic acid fermentation
by a yeast belonging to the genus Candida. Agric Biol Chem 45(2):475–479
67. Petruccioli M, Pulci V, Federici F (1999) Itaconic acid production by Aspergillus terreus on
raw starchy materials. Lett Appl Microbiol 28(4):309–312
68. Mondala AH (2015) Direct fungal fermentation of lignocellulosic biomass into itaconic, fumaric, and malic acids: current and future prospects. J Ind Microbiol Biotechnol
42(4):487–506
69. Yahiro K, Shibata S, Jia S-R, Park Y, Okabe M (1997) Efficient itaconic acid production from
raw corn starch. J Ferment Bioeng 84(4):375–377
70. Reddy CSK, Singh RP (2002) Enhanced production of itaconic acid from corn starch and
market refuse fruits by genetically manipulated Aspergillus terreus SKR10. Bioresour
Technol 85(1):69–71
71. Bafana R, Sivanesan S, Pandey RA (2017) Itaconic acid production by filamentous Fungi in
starch-rich industrial residues. Indian J Microbiol 57(3):322–328
72. Bafana R, Sivanesan S, Pandey R (2019) Optimization and scale up of itaconic acid production from potato starch waste in stirred tank bioreactor. Biotechnol Prog 35
73. Okamoto S, Chin T, Nagata K, Takahashi T, Ohara H, Aso Y (2015) Production of itaconic
acid in Escherichia coli expressing recombinant α-amylase using starch as substrate. J Biosci
Bioeng 119(5):548–553
74. Gnanasekaran R, Dhandapani B, Gopinath KP, Iyyappan J (2018a) Synthesis of itaconic
acid from agricultural waste using novel Aspergillus niveus. Prep Biochem Biotechnol
48(7):605–609
75. Petridis L, Smith JC (2018) Molecular-level driving forces in lignocellulosic biomass deconstruction for bioenergy. Nat Rev Chem 2(11):382–389
76. Kautola H (1990) Itaconic acid production from xylose in repeated-batch and continuous
bioreactors. Appl Microbiol Biotechnol 33(1):7–11
77. Saha BC, Kennedy GJ (2017) Mannose and galactose as substrates for production of itaconic
acid by Aspergillus terreus. Lett Appl Microbiol 65(6):527–533
78. Krull S, Eidt L, Hevekerl A, Kuenz A, Prüße U (2017) Itaconic acid production from wheat
chaff by Aspergillus terreus. Process Biochem 63:169–176
K. Avasthi et al.